These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90. Kang BH; Plescia J; Song HY; Meli M; Colombo G; Beebe K; Scroggins B; Neckers L; Altieri DC J Clin Invest; 2009 Mar; 119(3):454-64. PubMed ID: 19229106 [TBL] [Abstract][Full Text] [Related]
3. Hsp90 inhibitors disrupt mitochondrial homeostasis in cancer cells. Neckers L; Kern A; Tsutsumi S Chem Biol; 2007 Nov; 14(11):1204-6. PubMed ID: 18022558 [TBL] [Abstract][Full Text] [Related]
4. Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis. Ozören N; El-Deiry W Exp Cell Res; 2002 Dec; 281(2):175-81. PubMed ID: 12460647 [TBL] [Abstract][Full Text] [Related]
5. Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2. Gallerne C; Prola A; Lemaire C Biochim Biophys Acta; 2013 Jun; 1833(6):1356-66. PubMed ID: 23485394 [TBL] [Abstract][Full Text] [Related]
6. A Novel Class of Hsp90 C-Terminal Modulators Have Pre-Clinical Efficacy in Prostate Tumor Cells Without Induction of a Heat Shock Response. Armstrong HK; Koay YC; Irani S; Das R; Nassar ZD; ; Selth LA; Centenera MM; McAlpine SR; Butler LM Prostate; 2016 Dec; 76(16):1546-1559. PubMed ID: 27526951 [TBL] [Abstract][Full Text] [Related]
7. Inhibition of the mitochondrial Hsp90 chaperone network: a novel, efficient treatment strategy for cancer? Siegelin MD Cancer Lett; 2013 Jun; 333(2):133-46. PubMed ID: 23376257 [TBL] [Abstract][Full Text] [Related]
8. Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones. Kang BH; Altieri DC Oncogene; 2009 Oct; 28(42):3681-8. PubMed ID: 19648961 [TBL] [Abstract][Full Text] [Related]
9. Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors. Park HK; Jeong H; Ko E; Lee G; Lee JE; Lee SK; Lee AJ; Im JY; Hu S; Kim SH; Lee JH; Lee C; Kang S; Kang BH J Med Chem; 2017 Sep; 60(17):7569-7578. PubMed ID: 28816449 [TBL] [Abstract][Full Text] [Related]
10. Identification of heat shock protein 90 inhibitors to sensitize drug resistant side population tumor cells using a cell based assay platform. Sobhan PK; Seervi M; Joseph J; Chandrika BB; Varghese S; Santhoshkumar TR; Radhakrishna Pillai M Cancer Lett; 2012 Apr; 317(1):78-88. PubMed ID: 22085491 [TBL] [Abstract][Full Text] [Related]
11. Heat shock protein 90: a unique chemotherapeutic target. Cullinan SB; Whitesell L Semin Oncol; 2006 Aug; 33(4):457-65. PubMed ID: 16890800 [TBL] [Abstract][Full Text] [Related]
12. Alternate strategies of Hsp90 modulation for the treatment of cancer and other diseases. Brandt GE; Blagg BS Curr Top Med Chem; 2009; 9(15):1447-61. PubMed ID: 19860731 [TBL] [Abstract][Full Text] [Related]
13. The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways. Wang R; Shao F; Liu Z; Zhang J; Wang S; Liu J; Liu H; Chen H; Liu K; Xia M; Wang Y Chem Biol Interact; 2013 Sep; 205(1):1-10. PubMed ID: 23777986 [TBL] [Abstract][Full Text] [Related]
14. Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway. Wagatsuma A; Takayama Y; Hoshino T; Shiozuka M; Yamada S; Matsuda R; Mabuchi K Mol Cell Biochem; 2018 Aug; 445(1-2):45-58. PubMed ID: 29248972 [TBL] [Abstract][Full Text] [Related]
15. Combined effect of Hsp90 inhibitor geldanamycin and parthenolide via reactive oxygen species-mediated apoptotic process on epithelial ovarian cancer cells. Lee CS; Kim YJ; Lee SA; Myung SC; Kim W Basic Clin Pharmacol Toxicol; 2012 Sep; 111(3):173-81. PubMed ID: 22433057 [TBL] [Abstract][Full Text] [Related]
16. Global targeting of subcellular heat shock protein-90 networks for therapy of glioblastoma. Siegelin MD; Plescia J; Raskett CM; Gilbert CA; Ross AH; Altieri DC Mol Cancer Ther; 2010 Jun; 9(6):1638-46. PubMed ID: 20501802 [TBL] [Abstract][Full Text] [Related]
17. Mitochondria in cancer metabolism, an organelle whose time has come? Anderson RG; Ghiraldeli LP; Pardee TS Biochim Biophys Acta Rev Cancer; 2018 Aug; 1870(1):96-102. PubMed ID: 29807044 [TBL] [Abstract][Full Text] [Related]
18. Clinical Evaluation and Biomarker Profiling of Hsp90 Inhibitors. Yuno A; Lee MJ; Lee S; Tomita Y; Rekhtman D; Moore B; Trepel JB Methods Mol Biol; 2018; 1709():423-441. PubMed ID: 29177675 [TBL] [Abstract][Full Text] [Related]
19. C-terminal modulators of heat shock protein of 90 kDa (HSP90): State of development and modes of action. Bickel D; Gohlke H Bioorg Med Chem; 2019 Nov; 27(21):115080. PubMed ID: 31519378 [TBL] [Abstract][Full Text] [Related]
20. Detecting the Potential Pharmacological Synergy of Drug Combination by Viability Assays In Vitro. Gibbs BK; Sourbier C Methods Mol Biol; 2018; 1709():129-137. PubMed ID: 29177656 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]