BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 19307310)

  • 1. Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
    Padmakumar VC; Aleem E; Berthet C; Hilton MB; Kaldis P
    Mol Cell Biol; 2009 May; 29(10):2582-93. PubMed ID: 19307310
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
    Adon AM; Zeng X; Harrison MK; Sannem S; Kiyokawa H; Kaldis P; Saavedra HI
    Mol Cell Biol; 2010 Feb; 30(3):694-710. PubMed ID: 19933848
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mice thrive without Cdk4 and Cdk2.
    Barrière C; Santamaría D; Cerqueira A; Galán J; Martín A; Ortega S; Malumbres M; Dubus P; Barbacid M
    Mol Oncol; 2007 Jun; 1(1):72-83. PubMed ID: 19383288
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.
    Xie G; Habbersett RC; Jia Y; Peterson SR; Lehnert BE; Bradbury EM; D'Anna JA
    Oncogene; 1998 Feb; 16(6):721-36. PubMed ID: 9488036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.
    Gillam MP; Nimbalkar D; Sun L; Christov K; Ray D; Kaldis P; Liu X; Kiyokawa H
    Oncogene; 2015 Feb; 34(7):932-8. PubMed ID: 24531709
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks.
    Upton JW; van Dyk LF; Speck SH
    Virology; 2005 Oct; 341(2):271-83. PubMed ID: 16102793
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after gamma-irradiation.
    Bulavin DV; Tararova ND; Aksenov ND; Pospelov VA; Pospelova TV
    Oncogene; 1999 Oct; 18(41):5611-9. PubMed ID: 10523840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cdk2 deficiency decreases ras/CDK4-dependent malignant progression, but not myc-induced tumorigenesis.
    Macias E; Kim Y; Miliani de Marval PL; Klein-Szanto A; Rodriguez-Puebla ML
    Cancer Res; 2007 Oct; 67(20):9713-20. PubMed ID: 17942901
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
    Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
    Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genetic characterization of the role of the Cip/Kip family of proteins as cyclin-dependent kinase inhibitors and assembly factors.
    Cerqueira A; Martín A; Symonds CE; Odajima J; Dubus P; Barbacid M; Santamaría D
    Mol Cell Biol; 2014 Apr; 34(8):1452-9. PubMed ID: 24515438
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.
    Gogolin S; Ehemann V; Becker G; Brueckner LM; Dreidax D; Bannert S; Nolte I; Savelyeva L; Bell E; Westermann F
    Cell Cycle; 2013 Apr; 12(7):1091-104. PubMed ID: 23462184
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells.
    Kang J; Sergio CM; Sutherland RL; Musgrove EA
    BMC Cancer; 2014 Jan; 14():32. PubMed ID: 24444383
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of p21 by p53 following DNA damage inhibits both Cdk4 and Cdk2 activities.
    He G; Siddik ZH; Huang Z; Wang R; Koomen J; Kobayashi R; Khokhar AR; Kuang J
    Oncogene; 2005 Apr; 24(18):2929-43. PubMed ID: 15735718
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.
    Reynisdóttir I; Polyak K; Iavarone A; Massagué J
    Genes Dev; 1995 Aug; 9(15):1831-45. PubMed ID: 7649471
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2.
    Pack LR; Daigh LH; Chung M; Meyer T
    Nat Commun; 2021 Jun; 12(1):3356. PubMed ID: 34099663
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.
    Rao S; Lowe M; Herliczek TW; Keyomarsi K
    Oncogene; 1998 Nov; 17(18):2393-402. PubMed ID: 9811471
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acute renal failure during sepsis: potential role of cell cycle regulation.
    Yang QH; Liu DW; Long Y; Liu HZ; Chai WZ; Wang XT
    J Infect; 2009 Jun; 58(6):459-64. PubMed ID: 19428114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation.
    Minella AC; Swanger J; Bryant E; Welcker M; Hwang H; Clurman BE
    Curr Biol; 2002 Oct; 12(21):1817-27. PubMed ID: 12419181
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1).
    Martín A; Odajima J; Hunt SL; Dubus P; Ortega S; Malumbres M; Barbacid M
    Cancer Cell; 2005 Jun; 7(6):591-8. PubMed ID: 15950907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
    Prall OW; Sarcevic B; Musgrove EA; Watts CK; Sutherland RL
    J Biol Chem; 1997 Apr; 272(16):10882-94. PubMed ID: 9099745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.