These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 19307590)

  • 1. Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation.
    Quick M; Winther AM; Shi L; Nissen P; Weinstein H; Javitch JA
    Proc Natl Acad Sci U S A; 2009 Apr; 106(14):5563-8. PubMed ID: 19307590
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue.
    Zhao Y; Terry DS; Shi L; Quick M; Weinstein H; Blanchard SC; Javitch JA
    Nature; 2011 Jun; 474(7349):109-13. PubMed ID: 21516104
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Experimental conditions can obscure the second high-affinity site in LeuT.
    Quick M; Shi L; Zehnpfennig B; Weinstein H; Javitch JA
    Nat Struct Mol Biol; 2012 Jan; 19(2):207-11. PubMed ID: 22245968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites.
    Quick M; Abramyan AM; Wiriyasermkul P; Weinstein H; Shi L; Javitch JA
    Proc Natl Acad Sci U S A; 2018 Aug; 115(34):E7924-E7931. PubMed ID: 30082383
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context.
    Wang H; Elferich J; Gouaux E
    Nat Struct Mol Biol; 2012 Jan; 19(2):212-9. PubMed ID: 22245965
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mechanism of a neurotransmitter:sodium symporter--inward release of Na+ and substrate is triggered by substrate in a second binding site.
    Shi L; Quick M; Zhao Y; Weinstein H; Javitch JA
    Mol Cell; 2008 Jun; 30(6):667-77. PubMed ID: 18570870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site.
    Piscitelli CL; Krishnamurthy H; Gouaux E
    Nature; 2010 Dec; 468(7327):1129-32. PubMed ID: 21179170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue.
    Wang H; Gouaux E
    EMBO Rep; 2012 Sep; 13(9):861-6. PubMed ID: 22836580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR.
    Erlendsson S; Gotfryd K; Larsen FH; Mortensen JS; Geiger MA; van Rossum BJ; Oschkinat H; Gether U; Teilum K; Loland CJ
    Elife; 2017 Jan; 6():. PubMed ID: 28117663
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Substrate binding and formation of an occluded state in the leucine transporter.
    Celik L; Schiøtt B; Tajkhorshid E
    Biophys J; 2008 Mar; 94(5):1600-12. PubMed ID: 18024499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exploring the K
    Schmidt SG; Nygaard A; Mindell JA; Loland CJ
    Elife; 2024 Jan; 12():. PubMed ID: 38271216
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Coupled global and local changes direct substrate translocation by neurotransmitter-sodium symporter ortholog LeuT.
    Cheng MH; Bahar I
    Biophys J; 2013 Aug; 105(3):630-9. PubMed ID: 23931311
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The membrane protein LeuT in micellar systems: aggregation dynamics and detergent binding to the S2 site.
    Khelashvili G; LeVine MV; Shi L; Quick M; Javitch JA; Weinstein H
    J Am Chem Soc; 2013 Sep; 135(38):14266-75. PubMed ID: 23980525
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters.
    Claxton DP; Quick M; Shi L; de Carvalho FD; Weinstein H; Javitch JA; McHaourab HS
    Nat Struct Mol Biol; 2010 Jul; 17(7):822-9. PubMed ID: 20562855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Substrate and drug binding sites in LeuT.
    Nyola A; Karpowich NK; Zhen J; Marden J; Reith ME; Wang DN
    Curr Opin Struct Biol; 2010 Aug; 20(4):415-22. PubMed ID: 20739005
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Annular Lipids in the Functional Properties of Leucine Transporter LeuT Proteomicelles.
    LeVine MV; Khelashvili G; Shi L; Quick M; Javitch JA; Weinstein H
    Biochemistry; 2016 Feb; 55(6):850-9. PubMed ID: 26811944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT.
    Zhang YW; Tavoulari S; Sinning S; Aleksandrova AA; Forrest LR; Rudnick G
    Proc Natl Acad Sci U S A; 2018 Sep; 115(38):E8854-E8862. PubMed ID: 30181291
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A conserved leucine occupies the empty substrate site of LeuT in the Na(+)-free return state.
    Malinauskaite L; Said S; Sahin C; Grouleff J; Shahsavar A; Bjerregaard H; Noer P; Severinsen K; Boesen T; Schiøtt B; Sinning S; Nissen P
    Nat Commun; 2016 May; 7():11673. PubMed ID: 27221344
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release.
    Gotfryd K; Boesen T; Mortensen JS; Khelashvili G; Quick M; Terry DS; Missel JW; LeVine MV; Gourdon P; Blanchard SC; Javitch JA; Weinstein H; Loland CJ; Nissen P; Gether U
    Nat Commun; 2020 Feb; 11(1):1005. PubMed ID: 32081981
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of LeuT reveal conformational dynamics in the outward-facing states.
    Fan J; Xiao Y; Quick M; Yang Y; Sun Z; Javitch JA; Zhou X
    J Biol Chem; 2021; 296():100609. PubMed ID: 33811858
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.