These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 19330783)

  • 1. Structure and function of benzoylurea-derived alpha-helix mimetics targeting the Bcl-x(L)/Bak binding interface.
    Rodriguez JM; Ross NT; Katt WP; Dhar D; Lee GI; Hamilton AD
    ChemMedChem; 2009 Apr; 4(4):649-56. PubMed ID: 19330783
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction.
    Yin H; Lee GI; Sedey KA; Rodriguez JM; Wang HG; Sebti SM; Hamilton AD
    J Am Chem Soc; 2005 Apr; 127(15):5463-8. PubMed ID: 15826183
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.
    Yin H; Lee GI; Sedey KA; Kutzki O; Park HS; Orner BP; Ernst JT; Wang HG; Sebti SM; Hamilton AD
    J Am Chem Soc; 2005 Jul; 127(29):10191-6. PubMed ID: 16028929
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and modular parallel synthesis of a MCR derived alpha-helix mimetic protein-protein interaction inhibitor scaffold.
    Antuch W; Menon S; Chen QZ; Lu Y; Sakamuri S; Beck B; Schauer-Vukasinović V; Agarwal S; Hess S; Dömling A
    Bioorg Med Chem Lett; 2006 Mar; 16(6):1740-3. PubMed ID: 16427279
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Relaxation of the rigid backbone of an oligoamide-foldamer-based α-helix mimetic: identification of potent Bcl-xL inhibitors.
    Yap JL; Cao X; Vanommeslaeghe K; Jung KY; Peddaboina C; Wilder PT; Nan A; MacKerell AD; Smythe WR; Fletcher S
    Org Biomol Chem; 2012 Apr; 10(15):2928-33. PubMed ID: 22395339
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthetic inhibitors of extended helix-protein interactions based on a biphenyl 4,4'-dicarboxamide scaffold.
    Rodriguez JM; Nevola L; Ross NT; Lee GI; Hamilton AD
    Chembiochem; 2009 Mar; 10(5):829-33. PubMed ID: 19263447
    [No Abstract]   [Full Text] [Related]  

  • 7. Oligomerization of BH4-truncated Bcl-x(L) in solution.
    Wang Y; Cao R; Liu D; Chervin A; Yuan J; An J; Huang Z
    Biochem Biophys Res Commun; 2007 Oct; 361(4):1006-11. PubMed ID: 17692289
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Photocontrollable peptide-based switches target the anti-apoptotic protein Bcl-xL.
    Kneissl S; Loveridge EJ; Williams C; Crump MP; Allemann RK
    Chembiochem; 2008 Dec; 9(18):3046-54. PubMed ID: 19012295
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationships of Bak derived peptides: affinity and specificity modulations by amino acid replacement.
    Frey V; Viaud J; Subra G; Cauquil N; Guichou JF; Casara P; Grassy G; Chavanieu A
    Eur J Med Chem; 2008 May; 43(5):966-72. PubMed ID: 17692431
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chelerythrine and sanguinarine dock at distinct sites on BclXL that are not the classic BH3 binding cleft.
    Zhang YH; Bhunia A; Wan KF; Lee MC; Chan SL; Yu VC; Mok YK
    J Mol Biol; 2006 Dec; 364(3):536-49. PubMed ID: 17011577
    [TBL] [Abstract][Full Text] [Related]  

  • 11. NMR solution structure of a photoswitchable apoptosis activating Bak peptide bound to Bcl-xL.
    Wysoczanski P; Mart RJ; Loveridge EJ; Williams C; Whittaker SB; Crump MP; Allemann RK
    J Am Chem Soc; 2012 May; 134(18):7644-7. PubMed ID: 22515821
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rational design of new class of BH3-mimetics as inhibitors of the Bcl-xL protein.
    Pinto M; Orzaez Mdel M; Delgado-Soler L; Perez JJ; Rubio-Martinez J
    J Chem Inf Model; 2011 Jun; 51(6):1249-58. PubMed ID: 21528891
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein.
    Feng Y; Zhang L; Hu T; Shen X; Ding J; Chen K; Jiang H; Liu D
    Arch Biochem Biophys; 2009 Apr; 484(1):46-54. PubMed ID: 19161970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of conformationally constrained benzoylureas as BH3-mimetics.
    Brady RM; Hatzis E; Connor T; Street IP; Baell JB; Lessene G
    Org Biomol Chem; 2012 Jul; 10(27):5230-7. PubMed ID: 22648632
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Terephthalamide derivatives as mimetics of the helical region of Bak peptide target Bcl-xL protein.
    Yin H; Hamilton AD
    Bioorg Med Chem Lett; 2004 Mar; 14(6):1375-9. PubMed ID: 15006365
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel dimerization mode of the human Bcl-2 family protein Bak, a mitochondrial apoptosis regulator.
    Wang H; Takemoto C; Akasaka R; Uchikubo-Kamo T; Kishishita S; Murayama K; Terada T; Chen L; Liu ZJ; Wang BC; Sugano S; Tanaka A; Inoue M; Kigawa T; Shirouzu M; Yokoyama S
    J Struct Biol; 2009 Apr; 166(1):32-7. PubMed ID: 19135534
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure of an allosteric inhibitor of LFA-1 bound to the I-domain studied by crystallography, NMR, and calorimetry.
    Crump MP; Ceska TA; Spyracopoulos L; Henry A; Archibald SC; Alexander R; Taylor RJ; Findlow SC; O'Connell J; Robinson MK; Shock A
    Biochemistry; 2004 Mar; 43(9):2394-404. PubMed ID: 14992576
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Programmed anuclear cell death delimits platelet life span.
    Mason KD; Carpinelli MR; Fletcher JI; Collinge JE; Hilton AA; Ellis S; Kelly PN; Ekert PG; Metcalf D; Roberts AW; Huang DC; Kile BT
    Cell; 2007 Mar; 128(6):1173-86. PubMed ID: 17382885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological activities of new di- and trimeric quinoline derivatives.
    Broch S; Hénon H; Debaud AL; Fogeron ML; Bonnefoy-Bérard N; Anizon F; Moreau P
    Bioorg Med Chem; 2010 Oct; 18(19):7132-43. PubMed ID: 20800501
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and molecular modeling study of new trimeric quinoline derivatives.
    Saugues E; Nauton L; Théry V; Anizon F; Moreau P
    Bioorg Chem; 2011 Aug; 39(4):143-50. PubMed ID: 21807395
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.