BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 19331423)

  • 1. Total synthesis of Spiruchostatin A via chemoselective macrocyclization using an accessible enantiomerically pure latent thioester.
    Calandra NA; Cheng YL; Kocak KA; Miller JS
    Org Lett; 2009 May; 11(9):1971-4. PubMed ID: 19331423
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor.
    Yurek-George A; Habens F; Brimmell M; Packham G; Ganesan A
    J Am Chem Soc; 2004 Feb; 126(4):1030-1. PubMed ID: 14746465
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Total synthesis of the bicyclic depsipeptide HDAC inhibitors spiruchostatins A and B, 5''-epi-spiruchostatin B, FK228 (FR901228) and preliminary evaluation of their biological activity.
    Narita K; Kikuchi T; Watanabe K; Takizawa T; Oguchi T; Kudo K; Matsuhara K; Abe H; Yamori T; Yoshida M; Katoh T
    Chemistry; 2009 Oct; 15(42):11174-86. PubMed ID: 19760730
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The first biologically active synthetic analogues of FK228, the depsipeptide histone deacetylase inhibitor.
    Yurek-George A; Cecil AR; Mo AH; Wen S; Rogers H; Habens F; Maeda S; Yoshida M; Packham G; Ganesan A
    J Med Chem; 2007 Nov; 50(23):5720-6. PubMed ID: 17958342
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of cyclic peptides containing a thioester handle for native chemical ligation.
    van de Langemheen H; Brouwer AJ; Kemmink J; Kruijtzer JA; Liskamp RM
    J Org Chem; 2012 Nov; 77(22):10058-64. PubMed ID: 23078179
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Copper(I)-Mediated Denitrogenative Macrocyclization for the Synthesis of Cyclic α
    Chen CC; Wang SF; Su YY; Lin YA; Lin PC
    Chem Asian J; 2017 Jun; 12(12):1326-1337. PubMed ID: 28395122
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Total Synthesis of Skyllamycins A-C.
    Giltrap AM; Haeckl FPJ; Kurita KL; Linington RG; Payne RJ
    Chemistry; 2017 Oct; 23(60):15046-15049. PubMed ID: 28906041
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thioester-isocyanides: versatile reagents for the synthesis of cycle-tail peptides.
    Rotstein BH; Winternheimer DJ; Yin LM; Deber CM; Yudin AK
    Chem Commun (Camb); 2012 Apr; 48(31):3775-7. PubMed ID: 22430393
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and Biological Evaluation of a Depsipeptidic Histone Deacetylase Inhibitor via a Generalizable Approach Using an Optimized Latent Thioester Solid-Phase Linker.
    Zang X; Peraro L; Davison RT; Blum TR; Vallabhaneni D; Fennell CE; Cramer SL; Shah HK; Wholly DM; Fink EA; Sivak JT; Ingalls KM; Herr CT; Lawson VE; Burnett MR; Slade DJ; Cole KE; Carle SA; Miller JS
    J Org Chem; 2020 Jun; 85(12):8253-8260. PubMed ID: 32452203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of a potent histone deacetylase inhibitor.
    Liu T; Kapustin G; Etzkorn FA
    J Med Chem; 2007 May; 50(9):2003-6. PubMed ID: 17419603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222.
    Rodriquez M; Terracciano S; Cini E; Settembrini G; Bruno I; Bifulco G; Taddei M; Gomez-Paloma L
    Angew Chem Int Ed Engl; 2006 Jan; 45(3):423-7. PubMed ID: 16311994
    [No Abstract]   [Full Text] [Related]  

  • 12. Chemoselective cyclization of unprotected linear peptides by α-ketoacid-hydroxylamine amide-ligation.
    Fukuzumi T; Ju L; Bode JW
    Org Biomol Chem; 2012 Aug; 10(30):5837-44. PubMed ID: 22426859
    [TBL] [Abstract][Full Text] [Related]  

  • 13. cis-Apa: a practical linker for the microwave-assisted preparation of cyclic pseudopeptides via RCM cyclative cleavage.
    Baron A; Verdié P; Martinez J; Lamaty F
    J Org Chem; 2011 Feb; 76(3):766-72. PubMed ID: 21214240
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fmoc-based peptide thioester synthesis with self-purifying effect: heading to native chemical ligation in parallel formats.
    Thomas F
    J Pept Sci; 2013 Mar; 19(3):141-7. PubMed ID: 23389927
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Click chemistry as a macrocyclization tool in the solid-phase synthesis of small cyclic peptides.
    Turner RA; Oliver AG; Lokey RS
    Org Lett; 2007 Nov; 9(24):5011-4. PubMed ID: 17956112
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A convergent synthesis of the fully elaborated macrocyclic core of TMC-95A.
    Coste A; Bayle A; Marrot J; Evano G
    Org Lett; 2014 Mar; 16(5):1306-9. PubMed ID: 24559256
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and cytotoxicity of the depsipeptides analogues of callipeltin B.
    Kikuchi M; Watanabe Y; Tanaka M; Akaji K; Konno H
    Bioorg Med Chem Lett; 2011 Aug; 21(16):4865-8. PubMed ID: 21741837
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design and synthesis of mono and bicyclic tetrapeptides thioester as potent inhibitor of histone deacetylases.
    Hoque MA; Islam MS; Islam MN; Kato T; Nishino N; Ito A; Yoshida M
    Amino Acids; 2014 Oct; 46(10):2435-44. PubMed ID: 25048030
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterisation of the in vitro activity of the depsipeptide histone deacetylase inhibitor spiruchostatin A.
    Crabb SJ; Howell M; Rogers H; Ishfaq M; Yurek-George A; Carey K; Pickering BM; East P; Mitter R; Maeda S; Johnson PW; Townsend P; Shin-ya K; Yoshida M; Ganesan A; Packham G
    Biochem Pharmacol; 2008 Aug; 76(4):463-75. PubMed ID: 18611394
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solid-phase synthesis of an A-B loop mimetic of the Cepsilon3 domain of human IgE: macrocyclization by Sonogashira coupling.
    Spivey AC; McKendrick J; Srikaran R; Helm BA
    J Org Chem; 2003 Mar; 68(5):1843-51. PubMed ID: 12608800
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.