BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

90 related articles for article (PubMed ID: 19340835)

  • 1. Design and synthesis of a gossypol derivative with improved antitumor activities.
    Zhan Y; Jia G; Wu D; Xu Y; Xu L
    Arch Pharm (Weinheim); 2009 Apr; 342(4):223-9. PubMed ID: 19340835
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of XTT and Alamar blue assays in the assessment of the viability of various human cancer cell lines by AT-101 (-/- gossypol).
    Uzunoglu S; Karaca B; Atmaca H; Kisim A; Sezgin C; Karabulut B; Uslu R
    Toxicol Mech Methods; 2010 Oct; 20(8):482-6. PubMed ID: 20843265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apogossypolone, derivative of gossypol, mobilizes endogenous copper in human peripheral lymphocytes leading to oxidative DNA breakage.
    Zubair H; Khan HY; Ullah MF; Ahmad A; Wu D; Hadi SM
    Eur J Pharm Sci; 2012 Aug; 47(1):280-6. PubMed ID: 22554693
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.
    Wei J; Kitada S; Stebbins JL; Placzek W; Zhai D; Wu B; Rega MF; Zhang Z; Cellitti J; Yang L; Dahl R; Reed JC; Pellecchia M
    J Med Chem; 2010 Nov; 53(22):8000-11. PubMed ID: 21033669
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mobilization of Intracellular Copper by Gossypol and Apogossypolone Leads to Reactive Oxygen Species-Mediated Cell Death: Putative Anticancer Mechanism.
    Zubair H; Azim S; Khan HY; Ullah MF; Wu D; Singh AP; Hadi SM; Ahmad A
    Int J Mol Sci; 2016 Jun; 17(5):. PubMed ID: 27331811
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chiral gossypol derivatives: evaluation of their anticancer activity and molecular modeling.
    Zhang L; Jiang H; Cao X; Zhao H; Wang F; Cui Y; Jiang B
    Eur J Med Chem; 2009 Oct; 44(10):3961-72. PubMed ID: 19447525
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Developing gossypol derivatives with enhanced antitumor activity.
    Liang XS; Rogers AJ; Webber CL; Ormsby TJ; Tiritan ME; Matlin SA; Benz CC
    Invest New Drugs; 1995; 13(3):181-6. PubMed ID: 8729944
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ApoG2 inhibits the antiapoptotic protein, Mcl‑1, and induces mitochondria‑dependent apoptosis in human colorectal cancer cells.
    Li T; Yuan G; Zhang L; Ye L; Li S; Fan Y; Sun J
    Mol Med Rep; 2015 Nov; 12(5):6976-84. PubMed ID: 26352605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells.
    Xin J; Zhan YH; Xia LM; Zhu HW; Nie YZ; Liang JM; Tian J
    Biomed Pharmacother; 2013 Feb; 67(1):88-95. PubMed ID: 23201009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel water-soluble gossypol derivative increases chemotherapeutic sensitivity and promotes growth inhibition in colon cancer.
    Yan F; Cao XX; Jiang HX; Zhao XL; Wang JY; Lin YH; Liu QL; Zhang C; Jiang B; Guo F
    J Med Chem; 2010 Aug; 53(15):5502-10. PubMed ID: 20684596
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Profiling of angiogenic cytokines produced by hormone- and drug-refractory prostate cancer cell lines, PC-3 and DU-145 before and after treatment with gossypol.
    Karaca B; Kucukzeybek Y; Gorumlu G; Erten C; Gul MK; Cengiz E; Atmaca H; Uzunoglu S; Sanli UA; Karabulut B; Uslu R
    Eur Cytokine Netw; 2008 Dec; 19(4):176-84. PubMed ID: 19103523
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based design of potent small-molecule inhibitors of anti-apoptotic Bcl-2 proteins.
    Wang G; Nikolovska-Coleska Z; Yang CY; Wang R; Tang G; Guo J; Shangary S; Qiu S; Gao W; Yang D; Meagher J; Stuckey J; Krajewski K; Jiang S; Roller PP; Abaan HO; Tomita Y; Wang S
    J Med Chem; 2006 Oct; 49(21):6139-42. PubMed ID: 17034116
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro.
    Zhang XQ; Huang XF; Hu XB; Zhan YH; An QX; Yang SM; Xia AJ; Yi J; Chen R; Mu SJ; Wu DC
    Asian J Androl; 2010 Sep; 12(5):697-708. PubMed ID: 20657602
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antiproliferative activity of gossypol and gossypolone on human breast cancer cells.
    Gilbert NE; O'Reilly JE; Chang CJ; Lin YC; Brueggemeier RW
    Life Sci; 1995; 57(1):61-7. PubMed ID: 7596222
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and cytotoxicity of gossypol related compounds.
    Dao VT; Gaspard C; Mayer M; Werner GH; Nguyen SN; Michelot RJ
    Eur J Med Chem; 2000 Sep; 35(9):805-13. PubMed ID: 11006482
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells.
    Oliver CL; Bauer JA; Wolter KG; Ubell ML; Narayan A; O'Connell KM; Fisher SG; Wang S; Wu X; Ji M; Carey TE; Bradford CR
    Clin Cancer Res; 2004 Nov; 10(22):7757-63. PubMed ID: 15570010
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lactic dehydrogenase isozymes, 31P magnetic resonance spectroscopy, and in vitro antimitochondrial tumor toxicity with gossypol and rhodamine-123.
    Benz C; Hollander C; Keniry M; James TL; Mitchell M
    J Clin Invest; 1987 Feb; 79(2):517-23. PubMed ID: 3805280
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory effects of gossypol, gossypolone, and apogossypolone on a collection of economically important filamentous fungi.
    Mellon JE; Zelaya CA; Dowd MK; Beltz SB; Klich MA
    J Agric Food Chem; 2012 Mar; 60(10):2740-5. PubMed ID: 22324794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of gossypol atropisomers and derivatives and evaluation of their anti-proliferative and anti-oxidant activity.
    Dodou K; Anderson RJ; Lough WJ; Small DA; Shelley MD; Groundwater PW
    Bioorg Med Chem; 2005 Jul; 13(13):4228-37. PubMed ID: 15878283
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory effects of gossypol-related compounds on growth of Aspergillus flavus.
    Mellon JE; Zelaya CA; Dowd MK
    Lett Appl Microbiol; 2011 Apr; 52(4):406-12. PubMed ID: 21291481
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.