These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 19342246)

  • 1. Association of autophagy with cholesterol-accumulated compartments in Niemann-Pick disease type C cells.
    Ishibashi S; Yamazaki T; Okamoto K
    J Clin Neurosci; 2009 Jul; 16(7):954-9. PubMed ID: 19342246
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain.
    Liao G; Yao Y; Liu J; Yu Z; Cheung S; Xie A; Liang X; Bi X
    Am J Pathol; 2007 Sep; 171(3):962-75. PubMed ID: 17631520
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Automated microscopy screening for compounds that partially revert cholesterol accumulation in Niemann-Pick C cells.
    Pipalia NH; Huang A; Ralph H; Rujoi M; Maxfield FR
    J Lipid Res; 2006 Feb; 47(2):284-301. PubMed ID: 16288097
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Primary cilium alterations and expression changes of Patched1 proteins in niemann-pick type C disease.
    Formichi P; Battisti C; De Santi MM; Guazzo R; Tripodi SA; Radi E; Rossi B; Tarquini E; Federico A
    J Cell Physiol; 2018 Jan; 233(1):663-672. PubMed ID: 28332184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NPC1-containing compartment of human granulosa-lutein cells: a role in the intracellular trafficking of cholesterol supporting steroidogenesis.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Sun G; Glick JM; Patel S; Neufeld EB; Pentchev PG; Strauss JF
    Exp Cell Res; 2000 Feb; 255(1):56-66. PubMed ID: 10666334
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lung.
    Roszell BR; Tao JQ; Yu KJ; Huang S; Bates SR
    Am J Physiol Lung Cell Mol Physiol; 2012 May; 302(9):L919-32. PubMed ID: 22367786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane.
    Lusa S; Blom TS; Eskelinen EL; Kuismanen E; Månsson JE; Simons K; Ikonen E
    J Cell Sci; 2001 May; 114(Pt 10):1893-900. PubMed ID: 11329376
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.
    Makioka K; Yamazaki T; Kakuda S; Okamoto K
    Neurol Res; 2009 Nov; 31(9):959-68. PubMed ID: 19215663
    [TBL] [Abstract][Full Text] [Related]  

  • 9. β-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease.
    Tamura A; Yui N
    J Biol Chem; 2015 Apr; 290(15):9442-54. PubMed ID: 25713067
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein.
    Charman M; Kennedy BE; Osborne N; Karten B
    J Lipid Res; 2010 May; 51(5):1023-34. PubMed ID: 19965586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
    Frolov A; Srivastava K; Daphna-Iken D; Traub LM; Schaffer JE; Ory DS
    J Biol Chem; 2001 Dec; 276(49):46414-21. PubMed ID: 11571306
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection.
    Lu F; Liang Q; Abi-Mosleh L; Das A; De Brabander JK; Goldstein JL; Brown MS
    Elife; 2015 Dec; 4():. PubMed ID: 26646182
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
    Boadu E; Nelson RC; Francis GA
    Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Accumulation of cholera toxin and GM1 ganglioside in the early endosome of Niemann-Pick C1-deficient cells.
    Sugimoto Y; Ninomiya H; Ohsaki Y; Higaki K; Davies JP; Ioannou YA; Ohno K
    Proc Natl Acad Sci U S A; 2001 Oct; 98(22):12391-6. PubMed ID: 11675488
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons.
    Cheung NS; Koh CH; Bay BH; Qi RZ; Choy MS; Li QT; Wong KP; Whiteman M
    Biochem Biophys Res Commun; 2004 Mar; 315(2):408-17. PubMed ID: 14766223
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol.
    Cruz JC; Sugii S; Yu C; Chang TY
    J Biol Chem; 2000 Feb; 275(6):4013-21. PubMed ID: 10660558
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Niemann-Pick C variant detection by altered sphingolipid trafficking and correlation with mutations within a specific domain of NPC1.
    Sun X; Marks DL; Park WD; Wheatley CL; Puri V; O'Brien JF; Kraft DL; Lundquist PA; Patterson MC; Pagano RE; Snow K
    Am J Hum Genet; 2001 Jun; 68(6):1361-72. PubMed ID: 11349231
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease.
    Strauss K; Goebel C; Runz H; Möbius W; Weiss S; Feussner I; Simons M; Schneider A
    J Biol Chem; 2010 Aug; 285(34):26279-88. PubMed ID: 20554533
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biophysical impact of sphingosine and other abnormal lipid accumulation in Niemann-Pick disease type C cell models.
    Carreira AC; Pokorna S; Ventura AE; Walker MW; Futerman AH; Lloyd-Evans E; de Almeida RFM; Silva LC
    Biochim Biophys Acta Mol Cell Biol Lipids; 2021 Aug; 1866(8):158944. PubMed ID: 33892149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations in the leucine zipper motif and sterol-sensing domain inactivate the Niemann-Pick C1 glycoprotein.
    Watari H; Blanchette-Mackie EJ; Dwyer NK; Watari M; Neufeld EB; Patel S; Pentchev PG; Strauss JF
    J Biol Chem; 1999 Jul; 274(31):21861-6. PubMed ID: 10419504
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.