BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 19343765)

  • 1. Synthetic multimeric heptyl mannosides as potent antiadhesives of uropathogenic Escherichia coli.
    Gouin SG; Wellens A; Bouckaert J; Kovensky J
    ChemMedChem; 2009 May; 4(5):749-55. PubMed ID: 19343765
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological evaluation of mannosyl triazoles as FimH antagonists.
    Schwardt O; Rabbani S; Hartmann M; Abgottspon D; Wittwer M; Kleeb S; Zalewski A; Smieško M; Cutting B; Ernst B
    Bioorg Med Chem; 2011 Nov; 19(21):6454-73. PubMed ID: 21962988
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Clustering of Escherichia coli type-1 fimbrial adhesins by using multimeric heptyl α-D-mannoside probes with a carbohydrate core.
    Almant M; Moreau V; Kovensky J; Bouckaert J; Gouin SG
    Chemistry; 2011 Aug; 17(36):10029-38. PubMed ID: 21774001
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease.
    Sivignon A; Yan X; Alvarez Dorta D; Bonnet R; Bouckaert J; Fleury E; Bernard J; Gouin SG; Darfeuille-Michaud A; Barnich N
    mBio; 2015 Nov; 6(6):e01298-15. PubMed ID: 26578673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FimH antagonists for the oral treatment of urinary tract infections: from design and synthesis to in vitro and in vivo evaluation.
    Klein T; Abgottspon D; Wittwer M; Rabbani S; Herold J; Jiang X; Kleeb S; Lüthi C; Scharenberg M; Bezençon J; Gubler E; Pang L; Smiesko M; Cutting B; Schwardt O; Ernst B
    J Med Chem; 2010 Dec; 53(24):8627-41. PubMed ID: 21105658
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin.
    Bouckaert J; Berglund J; Schembri M; De Genst E; Cools L; Wuhrer M; Hung CS; Pinkner J; Slättegård R; Zavialov A; Choudhury D; Langermann S; Hultgren SJ; Wyns L; Klemm P; Oscarson S; Knight SD; De Greve H
    Mol Microbiol; 2005 Jan; 55(2):441-55. PubMed ID: 15659162
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.
    Jarvis C; Han Z; Kalas V; Klein R; Pinkner JS; Ford B; Binkley J; Cusumano CK; Cusumano Z; Mydock-McGrane L; Hultgren SJ; Janetka JW
    ChemMedChem; 2016 Feb; 11(4):367-73. PubMed ID: 26812660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thiazolylaminomannosides as potent antiadhesives of type 1 piliated Escherichia coli isolated from Crohn's disease patients.
    Brument S; Sivignon A; Dumych TI; Moreau N; Roos G; Guérardel Y; Chalopin T; Deniaud D; Bilyy RO; Darfeuille-Michaud A; Bouckaert J; Gouin SG
    J Med Chem; 2013 Jul; 56(13):5395-406. PubMed ID: 23795713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intervening with urinary tract infections using anti-adhesives based on the crystal structure of the FimH-oligomannose-3 complex.
    Wellens A; Garofalo C; Nguyen H; Van Gerven N; Slättegård R; Hernalsteens JP; Wyns L; Oscarson S; De Greve H; Hultgren S; Bouckaert J
    PLoS One; 2008 Apr; 3(4):e2040. PubMed ID: 18446213
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based drug design and optimization of mannoside bacterial FimH antagonists.
    Han Z; Pinkner JS; Ford B; Obermann R; Nolan W; Wildman SA; Hobbs D; Ellenberger T; Cusumano CK; Hultgren SJ; Janetka JW
    J Med Chem; 2010 Jun; 53(12):4779-92. PubMed ID: 20507142
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antiadhesion therapy for urinary tract infections--a balanced PK/PD profile proved to be key for success.
    Jiang X; Abgottspon D; Kleeb S; Rabbani S; Scharenberg M; Wittwer M; Haug M; Schwardt O; Ernst B
    J Med Chem; 2012 May; 55(10):4700-13. PubMed ID: 22519985
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes.
    Bouckaert J; Mackenzie J; de Paz JL; Chipwaza B; Choudhury D; Zavialov A; Mannerstedt K; Anderson J; Piérard D; Wyns L; Seeberger PH; Oscarson S; De Greve H; Knight SD
    Mol Microbiol; 2006 Sep; 61(6):1556-68. PubMed ID: 16930149
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut.
    Alvarez Dorta D; Sivignon A; Chalopin T; Dumych TI; Roos G; Bilyy RO; Deniaud D; Krammer EM; de Ruyck J; Lensink MF; Bouckaert J; Barnich N; Gouin SG
    Chembiochem; 2016 May; 17(10):936-52. PubMed ID: 26946458
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heptyl α-D-mannosides grafted on a β-cyclodextrin core to interfere with Escherichia coli adhesion: an in vivo multivalent effect.
    Bouckaert J; Li Z; Xavier C; Almant M; Caveliers V; Lahoutte T; Weeks SD; Kovensky J; Gouin SG
    Chemistry; 2013 Jun; 19(24):7847-55. PubMed ID: 23595913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of adhesion of type 1 fimbriated Escherichia coli to highly mannosylated ligands.
    Nagahori N; Lee RT; Nishimura S; Pagé D; Roy R; Lee YC
    Chembiochem; 2002 Sep; 3(9):836-44. PubMed ID: 12210984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile.
    Kleeb S; Pang L; Mayer K; Eris D; Sigl A; Preston RC; Zihlmann P; Sharpe T; Jakob RP; Abgottspon D; Hutter AS; Scharenberg M; Jiang X; Navarra G; Rabbani S; Smiesko M; Lüdin N; Bezençon J; Schwardt O; Maier T; Ernst B
    J Med Chem; 2015 Mar; 58(5):2221-39. PubMed ID: 25666045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of P-fimbriated Escherichia coli adhesion by multivalent galabiose derivatives studied by a live-bacteria application of surface plasmon resonance.
    Salminen A; Loimaranta V; Joosten JA; Khan AS; Hacker J; Pieters RJ; Finne J
    J Antimicrob Chemother; 2007 Sep; 60(3):495-501. PubMed ID: 17623698
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of an aggregation assay to screen FimH antagonists.
    Abgottspon D; Rölli G; Hosch L; Steinhuber A; Jiang X; Schwardt O; Cutting B; Smiesko M; Jenal U; Ernst B; Trampuz A
    J Microbiol Methods; 2010 Sep; 82(3):249-55. PubMed ID: 20620174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections.
    Mydock-McGrane L; Cusumano Z; Han Z; Binkley J; Kostakioti M; Hannan T; Pinkner JS; Klein R; Kalas V; Crowley J; Rath NP; Hultgren SJ; Janetka JW
    J Med Chem; 2016 Oct; 59(20):9390-9408. PubMed ID: 27689912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the carbohydrate recognition domain of the bacterial adhesin FimH: Design, synthesis and binding properties of mannoside ligands.
    Sperling O; Fuchs A; Lindhorst TK
    Org Biomol Chem; 2006 Nov; 4(21):3913-22. PubMed ID: 17047870
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.