BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 19346255)

  • 1. The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.
    Srinivasan S; Mir F; Huang JS; Khasawneh FT; Lam SC; Le Breton GC
    J Biol Chem; 2009 Jun; 284(24):16108-16117. PubMed ID: 19346255
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism.
    Xiang B; Zhang G; Ren H; Sunkara M; Morris AJ; Gartner TK; Smyth SS; Li Z
    PLoS One; 2012; 7(12):e51037. PubMed ID: 23236426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Costimulation of the Gi-coupled ADP receptor and the Gq-coupled TXA2 receptor is required for ERK2 activation in collagen-induced platelet aggregation.
    Roger S; Pawlowski M; Habib A; Jandrot-Perrus M; Rosa JP; Bryckaert M
    FEBS Lett; 2004 Jan; 556(1-3):227-35. PubMed ID: 14706855
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
    Kim S; Foster C; Lecchi A; Quinton TM; Prosser DM; Jin J; Cattaneo M; Kunapuli SP
    Blood; 2002 May; 99(10):3629-36. PubMed ID: 11986217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors.
    Jin J; Quinton TM; Zhang J; Rittenhouse SE; Kunapuli SP
    Blood; 2002 Jan; 99(1):193-8. PubMed ID: 11756171
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the platelet P2Y12 receptor for adenosine diphosphate potentiates the antiplatelet effect of prostacyclin.
    Cattaneo M; Lecchi A
    J Thromb Haemost; 2007 Mar; 5(3):577-82. PubMed ID: 17155953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Agonist concentration-dependent differential responsivity of a human platelet purinergic receptor: pharmacological and kinetic studies of aggregation, deaggregation and shape change responses mediated by the purinergic P2Y1 receptor in vitro.
    Maayani S; Schwarz TE; Patel ND; Craddock-Royal BD; Tagliente TM
    Platelets; 2003; 14(7-8):445-62. PubMed ID: 14713514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synergistic Inhibition of Both P2Y1 and P2Y12 Adenosine Diphosphate Receptors As Novel Approach to Rapidly Attenuate Platelet-Mediated Thrombosis.
    Gremmel T; Yanachkov IB; Yanachkova MI; Wright GE; Wider J; Undyala VV; Michelson AD; Frelinger AL; Przyklenk K
    Arterioscler Thromb Vasc Biol; 2016 Mar; 36(3):501-9. PubMed ID: 26743169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. P2Y12 ADP receptor-dependent tyrosine phosphorylation of proteins of 27 and 31 kDa in thrombin-stimulated human platelets.
    Fälker K; Lange D; Presek P
    Thromb Haemost; 2005 May; 93(5):880-8. PubMed ID: 15886804
    [TBL] [Abstract][Full Text] [Related]  

  • 10. P2Y₁₂ and EP3 antagonists promote the inhibitory effects of natural modulators of platelet aggregation that act via cAMP.
    Iyú D; Glenn JR; White AE; Fox SC; Dovlatova N; Heptinstall S
    Platelets; 2011; 22(7):504-15. PubMed ID: 21591981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Blockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxide.
    Kirkby NS; Lundberg MH; Chan MV; Vojnovic I; Solomon AB; Emerson M; Mitchell JA; Warner TD
    Proc Natl Acad Sci U S A; 2013 Sep; 110(39):15782-7. PubMed ID: 24003163
    [TBL] [Abstract][Full Text] [Related]  

  • 12. On the mechanism of plasmin-induced platelet aggregation. Implications of the dual role of granule ADP.
    Ishii-Watabe A; Uchida E; Mizuguchi H; Hayakawa T
    Biochem Pharmacol; 2000 Jun; 59(11):1345-55. PubMed ID: 10751543
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antiplatelet action of R-99224, an active metabolite of a novel thienopyridine-type G(i)-linked P2T antagonist, CS-747.
    Sugidachi A; Asai F; Yoneda K; Iwamura R; Ogawa T; Otsuguro K; Koike H
    Br J Pharmacol; 2001 Jan; 132(1):47-54. PubMed ID: 11156560
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Alkylthio-substituted platelet P2Y12 receptor antagonists reveal pharmacological identity between the rat brain Gi-linked ADP receptors and P2Y12.
    Vasiljev KS; Uri A; Laitinen JT
    Neuropharmacology; 2003 Jul; 45(1):145-54. PubMed ID: 12814667
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of clopidogrel administration to healthy volunteers on platelet phosphorylation events triggered by ADP.
    Contreres JO; Dupuy E; Job B; Habib A; Bryckaert M; Rosa JP; Simoneau G; Herbert JM; Savi P; Levy-Toledano S
    Br J Haematol; 2003 Feb; 120(4):633-42. PubMed ID: 12588350
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Can the PFA-100 be modified to detect P2Y12 inhibition?
    Pidcock M; Harrison P
    J Thromb Haemost; 2006 Jun; 4(6):1424-6. PubMed ID: 16706997
    [No Abstract]   [Full Text] [Related]  

  • 17. Adenosine receptor agonists deepen the inhibition of platelet aggregation by P2Y
    Boncler M; Wzorek J; Wolska N; Polak D; Watala C; Rozalski M
    Vascul Pharmacol; 2019 Feb; 113():47-56. PubMed ID: 30471364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lipid rafts are required in Galpha(i) signaling downstream of the P2Y12 receptor during ADP-mediated platelet activation.
    Quinton TM; Kim S; Jin J; Kunapuli SP
    J Thromb Haemost; 2005 May; 3(5):1036-41. PubMed ID: 15869601
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Curcumin by activation of adenosine A
    Rukoyatkina N; Shpakova V; Bogoutdinova A; Kharazova A; Mindukshev I; Gambaryan S
    Biochem Biophys Res Commun; 2022 Jan; 586():20-26. PubMed ID: 34823218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Benzoyl ATP is an antagonist of rat and human P2Y1 receptors and of platelet aggregation.
    Vigne P; Hechler B; Gachet C; Breittmayer JP; Frelin C
    Biochem Biophys Res Commun; 1999 Mar; 256(1):94-7. PubMed ID: 10066429
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.