BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

682 related articles for article (PubMed ID: 19350599)

  • 1. DNA cross-linking patterns induced by an antitumor-active trinuclear platinum complex and comparison with its dinuclear analogue.
    Zhu J; Zhao Y; Zhu Y; Wu Z; Lin M; He W; Wang Y; Chen G; Dong L; Zhang J; Lu Y; Guo Z
    Chemistry; 2009; 15(21):5245-53. PubMed ID: 19350599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unique DNA binding mode of antitumor trinuclear tridentate platinum(II) compound.
    Olivova R; Kasparkova J; Vrana O; Vojtiskova M; Suchankova T; Novakova O; He W; Guo Z; Brabec V
    Mol Pharm; 2011 Dec; 8(6):2368-78. PubMed ID: 22050363
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N
    Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of geometric isomerism in dinuclear platinum antitumor complexes on DNA interstrand cross-linking.
    Kaspárková J; Nováková O; Vrána O; Farrell N; Brabec V
    Biochemistry; 1999 Aug; 38(34):10997-1005. PubMed ID: 10460154
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)].
    Brabec V; Christofis P; Slámová M; Kostrhunová H; Nováková O; Najajreh Y; Gibson D; Kaspárková J
    Biochem Pharmacol; 2007 Jun; 73(12):1887-900. PubMed ID: 17400194
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of bridging ligands in determining DNA-binding ability and cross-linking patterns of dinuclear platinum(II) antitumour complexes.
    Zhu J; Lin M; Fan D; Wu Z; Chen Y; Zhang J; Lu Y; Guo Z
    Dalton Trans; 2009 Dec; (48):10889-95. PubMed ID: 20023919
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biophysical analysis of natural, double-helical DNA modified by a dinuclear platinum(II) organometallic compound in a cell-free medium.
    Marini V; Kasparkova J; Novakova O; Monsú Scolaro L; Romeo R; Brabec V
    J Biol Inorg Chem; 2002 Sep; 7(7-8):725-34. PubMed ID: 12203009
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A; Berners-Price SJ; Davies MS; Thomas DS; Humphreys AS; Farrell N
    J Am Chem Soc; 2004 Feb; 126(7):2166-80. PubMed ID: 14971952
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.
    Kasparkova J; Vojtiskova M; Natile G; Brabec V
    Chemistry; 2008; 14(4):1330-41. PubMed ID: 18022972
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies.
    Kaspárková J; Mellish KJ; Qu Y; Brabec V; Farrell N
    Biochemistry; 1996 Dec; 35(51):16705-13. PubMed ID: 8988007
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.
    Téletchéa S; Skauge T; Sletten E; Kozelka J
    Chemistry; 2009 Nov; 15(45):12320-37. PubMed ID: 19813235
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.
    Baruah H; Wright MW; Bierbach U
    Biochemistry; 2005 Apr; 44(16):6059-70. PubMed ID: 15835895
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding.
    Kasparkova J; Vrana O; Farrell N; Brabec V
    J Inorg Biochem; 2004 Oct; 98(10):1560-9. PubMed ID: 15458817
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cross-links of quadruplex structures from human telomeric DNA by dinuclear platinum complexes show the flexibility of both structures.
    Ourliac-Garnier I; Elizondo-Riojas MA; Redon S; Farrell NP; Bombard S
    Biochemistry; 2005 Aug; 44(31):10620-34. PubMed ID: 16060671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular interaction of DNA with bisplatinum(II) complexes having bis(vicinal 1,2-diamines) as ligand.
    Büning H; Altman J; Beck W; Zorbas H
    Biochemistry; 1997 Sep; 36(38):11408-18. PubMed ID: 9298960
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Head-to-head cross-linked adduct between the antitumor unit bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) and the DNA fragment d(GpG).
    Chifotides HT; Dunbar KR
    Chemistry; 2006 Aug; 12(25):6458-68. PubMed ID: 16900545
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.
    Kasparkova J; Marini V; Najajreh Y; Gibson D; Brabec V
    Biochemistry; 2003 May; 42(20):6321-32. PubMed ID: 12755637
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II).
    Chifotides HT; Koshlap KM; Pérez LM; Dunbar KR
    J Am Chem Soc; 2003 Sep; 125(35):10714-24. PubMed ID: 12940757
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic insights into antitumor effects of new dinuclear cis Pt(II) complexes containing aromatic linkers.
    Zerzankova L; Kostrhunova H; Vojtiskova M; Novakova O; Suchankova T; Lin M; Guo Z; Kasparkova J; Brabec V
    Biochem Pharmacol; 2010 Aug; 80(3):344-51. PubMed ID: 20399754
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, cytotoxicity, cell uptake and DNA interstrand cross-linking of 4,4'-dipyrazolylmethane-linked multinuclear platinum anti-cancer complexes.
    Wheate NJ; Cullinane C; Webster LK; Collins JG
    Anticancer Drug Des; 2001; 16(2-3):91-8. PubMed ID: 11962517
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.