143 related articles for article (PubMed ID: 19362835)
1. Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog.
Ohwada J; Ozawa S; Kohchi M; Fukuda H; Murasaki C; Suda H; Murata T; Niizuma S; Tsukazaki M; Ori K; Yoshinari K; Itezono Y; Endo M; Ura M; Tanimura H; Miyazaki Y; Kawashima A; Nagao S; Namba E; Ogawa K; Kobayashi K; Okabe H; Umeda I; Shimma N
Bioorg Med Chem Lett; 2009 May; 19(10):2772-6. PubMed ID: 19362835
[TBL] [Abstract][Full Text] [Related]
2. A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts.
Endo M; Miwa M; Ura M; Tanimura H; Taniguchi K; Miyazaki Y; Ohwada J; Tsukazaki M; Niizuma S; Murata T; Ozawa S; Suda H; Ogawa K; Nanba E; Nagao S; Shimma N; Yamada-Okabe H
Cancer Chemother Pharmacol; 2010 Jan; 65(2):363-71. PubMed ID: 19495753
[TBL] [Abstract][Full Text] [Related]
3. Synthesis of new camptothecin analogs with improved antitumor activities.
Niizuma S; Tsukazaki M; Suda H; Murata T; Ohwada J; Ozawa S; Fukuda H; Murasaki C; Kohchi M; Morikami K; Yoshinari K; Endo M; Ura M; Tanimura H; Miyazaki Y; Takasuka T; Kawashima A; Nanba E; Nakano K; Ogawa K; Kobayashi K; Okabe H; Umeda I; Shimma N
Bioorg Med Chem Lett; 2009 Apr; 19(7):2018-21. PubMed ID: 19254843
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of bis and monocarbonate prodrugs of 10-hydroxycamptothecins.
He X; Lu W; Jiang X; Cai J; Zhang X; Ding J
Bioorg Med Chem; 2004 Aug; 12(15):4003-8. PubMed ID: 15246077
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of novel A-ring modified hexacyclic camptothecin analogues.
Kim DK; Ryu DH; Lee JY; Lee N; Kim YW; Kim JS; Chang K; Im GJ; Kim TK; Choi WS
J Med Chem; 2001 May; 44(10):1594-602. PubMed ID: 11334569
[TBL] [Abstract][Full Text] [Related]
6. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.
Schmid B; Chung DE; Warnecke A; Fichtner I; Kratz F
Bioconjug Chem; 2007; 18(3):702-16. PubMed ID: 17378599
[TBL] [Abstract][Full Text] [Related]
7. Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy.
Warnecke A; Kratz F
Bioconjug Chem; 2003; 14(2):377-87. PubMed ID: 12643748
[TBL] [Abstract][Full Text] [Related]
8. Kinetics and mechanisms of activation of alpha-amino acid ester prodrugs of camptothecins.
Song L; Bevins R; Anderson BD
J Med Chem; 2006 Jul; 49(14):4344-55. PubMed ID: 16821794
[TBL] [Abstract][Full Text] [Related]
9. Tripartate poly(ethylene glycol) prodrugs of the open lactone form of camptothecin.
Greenwald RB; Zhao H; Xia J
Bioorg Med Chem; 2003 Jun; 11(12):2635-9. PubMed ID: 12757729
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
Zhu L; Zhang X; Lei N; Liu W; Miao Z; Zhuang C; Sheng C; Guo W; Dong G; Yao J; Cheng P; Zhang W
Chem Biodivers; 2012 Jun; 9(6):1084-94. PubMed ID: 22700227
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biological evaluation of novel 10-substituted-7-ethyl-10-hydroxycamptothecin (SN-38) prodrugs.
Zhou M; Liu M; He X; Yu H; Wu D; Yao Y; Fan S; Zhang P; Shi W; Zhong B
Molecules; 2014 Nov; 19(12):19718-31. PubMed ID: 25438082
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues.
Sugimori M; Ejima A; Ohsuki S; Uoto K; Mitsui I; Kawato Y; Hirota Y; Sato K; Terasawa H
J Med Chem; 1998 Jun; 41(13):2308-18. PubMed ID: 9632364
[TBL] [Abstract][Full Text] [Related]
13. In vivo antitumor activity of two new seven-substituted water-soluble camptothecin analogues.
Emerson DL; Besterman JM; Brown HR; Evans MG; Leitner PP; Luzzio MJ; Shaffer JE; Sternbach DD; Uehling D; Vuong A
Cancer Res; 1995 Feb; 55(3):603-9. PubMed ID: 7834631
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of water-soluble glucuronide derivatives of camptothecin for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT).
Leu YL; Roffler SR; Chern JW
J Med Chem; 1999 Sep; 42(18):3623-8. PubMed ID: 10479293
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and antitumor activity of the hexacyclic camptothecin derivatives.
Gao H; Zhang X; Chen Y; Shen H; Pang T; Sun J; Xu C; Ding J; Li C; Lu W
Bioorg Med Chem Lett; 2005 Jul; 15(13):3233-6. PubMed ID: 15913996
[TBL] [Abstract][Full Text] [Related]
16. Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker.
Conover CD; Greenwald RB; Pendri A; Gilbert CW; Shum KL
Cancer Chemother Pharmacol; 1998; 42(5):407-14. PubMed ID: 9771956
[TBL] [Abstract][Full Text] [Related]
17. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo.
Mitsui I; Kumazawa E; Hirota Y; Aonuma M; Sugimori M; Ohsuki S; Uoto K; Ejima A; Terasawa H; Sato K
Jpn J Cancer Res; 1995 Aug; 86(8):776-82. PubMed ID: 7559102
[TBL] [Abstract][Full Text] [Related]
18. Novel fluoro-substituted camptothecins: in vivo antitumor activity, reduced gastrointestinal toxicity and pharmacokinetic characterization.
Rose WC; Marathe PH; Jang GR; Monticello TM; Balasubramanian BN; Long B; Fairchild CR; Wall ME; Wani MC
Cancer Chemother Pharmacol; 2006 Jul; 58(1):73-85. PubMed ID: 16228206
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of hypoxia-activated prodrugs of SN-38.
Jin C; Zhang Q; Lu W
Eur J Med Chem; 2017 May; 132():135-141. PubMed ID: 28350997
[TBL] [Abstract][Full Text] [Related]
20. Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
Lavergne O; Lesueur-Ginot L; Pla Rodas F; Kasprzyk PG; Pommier J; Demarquay D; Prévost G; Ulibarri G; Rolland A; Schiano-Liberatore AM; Harnett J; Pons D; Camara J; Bigg DC
J Med Chem; 1998 Dec; 41(27):5410-9. PubMed ID: 9876111
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
