180 related articles for article (PubMed ID: 19369081)
1. Molecular dynamics simulations on the critical states of the farnesyltransferase enzyme.
Sousa SF; Fernandes PA; Ramos MJ
Bioorg Med Chem; 2009 May; 17(9):3369-78. PubMed ID: 19369081
[TBL] [Abstract][Full Text] [Related]
2. Enzyme flexibility and the catalytic mechanism of farnesyltransferase: targeting the relation.
Sousa SF; Fernandes PA; Ramos MJ
J Phys Chem B; 2008 Jul; 112(29):8681-91. PubMed ID: 18572907
[TBL] [Abstract][Full Text] [Related]
3. Molecular dynamics analysis of a series of 22 potential farnesyltransferase substrates containing a CaaX-motif.
Sousa SF; Coimbra JT; Paramos D; Pinto R; Guimarães RS; Teixeira V; Fernandes PA; Ramos MJ
J Mol Model; 2013 Feb; 19(2):673-88. PubMed ID: 23011608
[TBL] [Abstract][Full Text] [Related]
4. Theoretical studies on farnesyl transferase: evidence for thioether product coordination to the active-site zinc sphere.
Sousa SF; Fernandes PA; Ramos MJ
J Comput Chem; 2007 May; 28(7):1160-8. PubMed ID: 17342704
[TBL] [Abstract][Full Text] [Related]
5. Protein farnesyl transferase target selectivity is dependent upon peptide stimulated product release.
Troutman JM; Andres DA; Spielmann HP
Biochemistry; 2007 Oct; 46(40):11299-309. PubMed ID: 17877368
[TBL] [Abstract][Full Text] [Related]
6. Computational studies of the farnesyltransferase ternary complex part I: substrate binding.
Cui G; Wang B; Merz KM
Biochemistry; 2005 Dec; 44(50):16513-23. PubMed ID: 16342942
[TBL] [Abstract][Full Text] [Related]
7. Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
Long SB; Casey PJ; Beese LS
Biochemistry; 1998 Jul; 37(27):9612-8. PubMed ID: 9657673
[TBL] [Abstract][Full Text] [Related]
8. Theoretical studies on farnesyltransferase: the distances paradox explained.
Sousa SF; Fernandes PA; Ramos MJ
Proteins; 2007 Jan; 66(1):205-18. PubMed ID: 17068802
[TBL] [Abstract][Full Text] [Related]
9. Computational and conformational evaluation of FTase alternative substrates: insight into a novel enzyme binding pocket.
Henriksen BS; Zahn TJ; Evanseck JD; Firestine SM; Gibbs RA
J Chem Inf Model; 2005; 45(4):1047-52. PubMed ID: 16045300
[TBL] [Abstract][Full Text] [Related]
10. Finding a needle in the haystack: computational modeling of Mg2+ binding in the active site of protein farnesyltransferase.
Yang Y; Chakravorty DK; Merz KM
Biochemistry; 2010 Nov; 49(44):9658-66. PubMed ID: 20923173
[TBL] [Abstract][Full Text] [Related]
11. Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
Terry KL; Casey PJ; Beese LS
Biochemistry; 2006 Aug; 45(32):9746-55. PubMed ID: 16893176
[TBL] [Abstract][Full Text] [Related]
12. Measurement of the alpha-secondary kinetic isotope effect for the reaction catalyzed by mammalian protein farnesyltransferase.
Pais JE; Bowers KE; Fierke CA
J Am Chem Soc; 2006 Nov; 128(47):15086-7. PubMed ID: 17117849
[TBL] [Abstract][Full Text] [Related]
13. Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem.
Sousa SF; Fernandes PA; Ramos MJ
Curr Med Chem; 2008; 15(15):1478-92. PubMed ID: 18537624
[TBL] [Abstract][Full Text] [Related]
14. Evidence for a catalytic role of zinc in protein farnesyltransferase. Spectroscopy of Co2+-farnesyltransferase indicates metal coordination of the substrate thiolate.
Huang CC; Casey PJ; Fierke CA
J Biol Chem; 1997 Jan; 272(1):20-3. PubMed ID: 8995218
[TBL] [Abstract][Full Text] [Related]
15. Selective modification of CaaX peptides with ortho-substituted anilinogeranyl lipids by protein farnesyl transferase: competitive substrates and potent inhibitors from a library of farnesyl diphosphate analogues.
Troutman JM; Subramanian T; Andres DA; Spielmann HP
Biochemistry; 2007 Oct; 46(40):11310-21. PubMed ID: 17854205
[TBL] [Abstract][Full Text] [Related]
16. Kinetic analysis of zinc ligand mutants of mammalian protein farnesyltransferase.
Fu HW; Beese LS; Casey PJ
Biochemistry; 1998 Mar; 37(13):4465-72. PubMed ID: 9521766
[TBL] [Abstract][Full Text] [Related]
17. Kinetic studies of protein farnesyltransferase mutants establish active substrate conformation.
Pickett JS; Bowers KE; Hartman HL; Fu HW; Embry AC; Casey PJ; Fierke CA
Biochemistry; 2003 Aug; 42(32):9741-8. PubMed ID: 12911316
[TBL] [Abstract][Full Text] [Related]
18. The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics.
Long SB; Hancock PJ; Kral AM; Hellinga HW; Beese LS
Proc Natl Acad Sci U S A; 2001 Nov; 98(23):12948-53. PubMed ID: 11687658
[TBL] [Abstract][Full Text] [Related]
19. Yeast protein farnesyltransferase: a pre-steady-state kinetic analysis.
Mathis JR; Poulter CD
Biochemistry; 1997 May; 36(21):6367-76. PubMed ID: 9174352
[TBL] [Abstract][Full Text] [Related]
20. Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity.
Reid TS; Terry KL; Casey PJ; Beese LS
J Mol Biol; 2004 Oct; 343(2):417-33. PubMed ID: 15451670
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
