489 related articles for article (PubMed ID: 19370747)
1. Design, synthesis, and biological evaluation of artificial macrosphelides in the search for new apoptosis-inducing agents.
Matsuya Y; Kobayashi Y; Kawaguchi T; Hori A; Watanabe Y; Ishihara K; Ahmed K; Wei ZL; Yu DY; Zhao QL; Kondo T; Nemoto H
Chemistry; 2009 Jun; 15(23):5799-813. PubMed ID: 19370747
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of macrosphelides with a thiazole side chain: new antitumor candidates having apoptosis-inducing property.
Matsuya Y; Kawaguchi T; Ishihara K; Ahmed K; Zhao QL; Kondo T; Nemoto H
Org Lett; 2006 Sep; 8(20):4609-12. PubMed ID: 16986962
[TBL] [Abstract][Full Text] [Related]
3. C-15 thiazol-4-yl analogues of (E)-9,10-didehydroepothilone D: synthesis and cytotoxicity.
Hearn BR; Zhang D; Li Y; Myles DC
Org Lett; 2006 Jul; 8(14):3057-9. PubMed ID: 16805551
[TBL] [Abstract][Full Text] [Related]
4. Design, total synthesis, and evaluation of novel open-chain epothilone analogues.
Alhamadsheh MM; Hudson RA; Viranga Tillekeratne LM
Org Lett; 2006 Feb; 8(4):685-8. PubMed ID: 16468742
[TBL] [Abstract][Full Text] [Related]
5. Complex target-oriented total synthesis in the drug discovery process: the discovery of a highly promising family of second generation epothilones.
Rivkin A; Yoshimura F; Gabarda AE; Chou TC; Dong H; Tong WP; Danishefsky SJ
J Am Chem Soc; 2003 Mar; 125(10):2899-901. PubMed ID: 12617656
[TBL] [Abstract][Full Text] [Related]
6. Total synthesis of hypermodified epothilone analogs with potent in vitro antitumor activity.
Kuzniewski CN; Gertsch J; Wartmann M; Altmann KH
Org Lett; 2008 Mar; 10(6):1183-6. PubMed ID: 18303900
[TBL] [Abstract][Full Text] [Related]
7. Application of ring-closing metathesis reactions in the synthesis of epothilones.
Rivkin A; Cho YS; Gabarda AE; Yoshimura F; Danishefsky SJ
J Nat Prod; 2004 Feb; 67(2):139-43. PubMed ID: 14987048
[TBL] [Abstract][Full Text] [Related]
8. Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.
Feyen F; Cachoux F; Gertsch J; Wartmann M; Altmann KH
Acc Chem Res; 2008 Jan; 41(1):21-31. PubMed ID: 18159935
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological properties of highly potent epothilone B analogues.
Nicolaou KC; Sasmal PK; Rassias G; Reddy MV; Altmann KH; Wartmann M; O'Brate A; Giannakakou P
Angew Chem Int Ed Engl; 2003 Aug; 42(30):3515-20. PubMed ID: 12900969
[No Abstract] [Full Text] [Related]
10. New antitumor imidazo[2,1-b]thiazole guanylhydrazones and analogues.
Andreani A; Burnelli S; Granaiola M; Leoni A; Locatelli A; Morigi R; Rambaldi M; Varoli L; Calonghi N; Cappadone C; Farruggia G; Zini M; Stefanelli C; Masotti L; Radin NS; Shoemaker RH
J Med Chem; 2008 Feb; 51(4):809-16. PubMed ID: 18251494
[TBL] [Abstract][Full Text] [Related]
11. Conformation-activity relationships in polyketide natural products: a new perspective on the rational design of epothilone analogues.
Taylor RE; Chen Y; Beatty A; Myles DC; Zhou Y
J Am Chem Soc; 2003 Jan; 125(1):26-7. PubMed ID: 12515494
[TBL] [Abstract][Full Text] [Related]
12. Total syntheses of [17]- and [18]dehydrodesoxyepothilones B via a concise ring-closing metathesis-based strategy: correlation of ring size with biological activity in the epothilone series.
Rivkin A; Njardarson JT; Biswas K; Chou TC; Danishefsky SJ
J Org Chem; 2002 Nov; 67(22):7737-40. PubMed ID: 12398497
[TBL] [Abstract][Full Text] [Related]
13. Epothilone analogues with benzimidazole and quinoline side chains: chemical synthesis, antiproliferative activity, and interactions with tubulin.
Dietrich SA; Lindauer R; Stierlin C; Gertsch J; Matesanz R; Notararigo S; Díaz JF; Altmann KH
Chemistry; 2009 Oct; 15(39):10144-57. PubMed ID: 19697384
[TBL] [Abstract][Full Text] [Related]
14. Design and total synthesis of a superior family of epothilone analogues, which eliminate xenograft tumors to a nonrelapsable state.
Chou TC; Dong H; Rivkin A; Yoshimura F; Gabarda AE; Cho YS; Tong WP; Danishefsky SJ
Angew Chem Int Ed Engl; 2003 Oct; 42(39):4762-7. PubMed ID: 14562342
[No Abstract] [Full Text] [Related]
15. On the remarkable antitumor properties of fludelone: how we got there.
Rivkin A; Chou TC; Danishefsky SJ
Angew Chem Int Ed Engl; 2005 May; 44(19):2838-50. PubMed ID: 15880547
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of epothilones A and B in solid and solution phase.
Nicolaou KC; Winssinger N; Pastor J; Ninkovic S; Sarabia F; He Y; Vourloumis D; Yang Z; Li T; Giannakakou P; Hamel E
Nature; 1997 May; 387(6630):268-72. PubMed ID: 9153390
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and antitumor evaluation of new thiazolo[5,4-b]quinoline derivatives.
Alvarez-Ibarra C; Fernández-Granda R; Quiroga ML; Carbonell A; Cárdenas F; Giralt E
J Med Chem; 1997 Feb; 40(5):668-76. PubMed ID: 9057853
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of bridged epothilone D analogues.
Chen QH; Ganesh T; Brodie P; Slebodnick C; Jiang Y; Banerjee A; Bane S; Snyder JP; Kingston DG
Org Biomol Chem; 2008 Dec; 6(24):4542-52. PubMed ID: 19039362
[TBL] [Abstract][Full Text] [Related]
19. Regioselective synthesis of folate receptor-targeted agents derived from epothilone analogs and folic acid.
Vlahov IR; Vite GD; Kleindl PJ; Wang Y; Santhapuram HK; You F; Howard SJ; Kim SH; Lee FF; Leamon CP
Bioorg Med Chem Lett; 2010 Aug; 20(15):4578-81. PubMed ID: 20594844
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and in vitro antitumor activity of new 1,4-diarylimidazole-2-ones and their 2-thione analogues.
Congiu C; Cocco MT; Onnis V
Bioorg Med Chem Lett; 2008 Feb; 18(3):989-93. PubMed ID: 18164978
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
