These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 19371318)

  • 1. In vitro and in vivo glucuronidation of midazolam in humans.
    Hyland R; Osborne T; Payne A; Kempshall S; Logan YR; Ezzeddine K; Jones B
    Br J Clin Pharmacol; 2009 Apr; 67(4):445-54. PubMed ID: 19371318
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Contribution of the N-glucuronidation pathway to the overall in vitro metabolic clearance of midazolam in humans.
    Klieber S; Hugla S; Ngo R; Arabeyre-Fabre C; Meunier V; Sadoun F; Fedeli O; Rival M; Bourrie M; Guillou F; Maurel P; Fabre G
    Drug Metab Dispos; 2008 May; 36(5):851-62. PubMed ID: 18256203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomes.
    Zhu B; Bush D; Doss GA; Vincent S; Franklin RB; Xu S
    Drug Metab Dispos; 2008 Feb; 36(2):331-8. PubMed ID: 17998299
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A; Satoh H; Thomas PE; Bush E; Moore D
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone.
    Mäenpää J; Hall SD; Ring BJ; Strom SC; Wrighton SA
    Pharmacogenetics; 1998 Apr; 8(2):137-55. PubMed ID: 10022752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of age on in vitro midazolam biotransformation in male CD-1 mouse liver microsomes.
    Warrington JS; Poku JW; von Moltke LL; Shader RI; Harmatz JS; Greenblatt DJ
    J Pharmacol Exp Ther; 2000 Mar; 292(3):1024-31. PubMed ID: 10688619
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Physiologically Based Pharmacokinetic Modeling to Predict the Impact of Liver Cirrhosis on Glucuronidation via UGT1A4 and UGT2B7/2B4-A Case Study with Midazolam.
    Ozbey AC; Keemink J; Wagner B; Pugliano A; Krähenbühl S; Annaert P; Fowler S; Parrott N; Umehara K
    Drug Metab Dispos; 2024 Jun; 52(7):614-625. PubMed ID: 38653501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytochrome P450-dependent metabolism of midazolam in hepatic microsomes from chickens, turkeys, pheasant and bobwhite quail.
    Cortright KA; Craigmill AL
    J Vet Pharmacol Ther; 2006 Dec; 29(6):469-76. PubMed ID: 17083450
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flavonoids diosmetin and luteolin inhibit midazolam metabolism by human liver microsomes and recombinant CYP 3A4 and CYP3A5 enzymes.
    Quintieri L; Palatini P; Nassi A; Ruzza P; Floreani M
    Biochem Pharmacol; 2008 Mar; 75(6):1426-37. PubMed ID: 18191104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Midazolam and triazolam biotransformation in mouse and human liver microsomes: relative contribution of CYP3A and CYP2C isoforms.
    Perloff MD; von Moltke LL; Court MH; Kotegawa T; Shader RI; Greenblatt DJ
    J Pharmacol Exp Ther; 2000 Feb; 292(2):618-28. PubMed ID: 10640299
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression.
    Perloff MD; Von Moltke LL; Greenblatt DJ
    Xenobiotica; 2003 Apr; 33(4):365-77. PubMed ID: 12745872
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cooperative binding of midazolam with testosterone and alpha-naphthoflavone within the CYP3A4 active site: a NMR T1 paramagnetic relaxation study.
    Cameron MD; Wen B; Allen KE; Roberts AG; Schuman JT; Campbell AP; Kunze KL; Nelson SD
    Biochemistry; 2005 Nov; 44(43):14143-51. PubMed ID: 16245930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of 1'- and 4-hydroxymidazolam by glucuronide conjugation is largely mediated by UDP-glucuronosyltransferases 1A4, 2B4, and 2B7.
    Seo KA; Bae SK; Choi YK; Choi CS; Liu KH; Shin JG
    Drug Metab Dispos; 2010 Nov; 38(11):2007-13. PubMed ID: 20713656
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Heterotropic activation of the midazolam hydroxylase activity of CYP3A by a positive allosteric modulator of mGlu5: in vitro to in vivo translation and potential impact on clinically relevant drug-drug interactions.
    Blobaum AL; Bridges TM; Byers FW; Turlington ML; Mattmann ME; Morrison RD; Mackie C; Lavreysen H; Bartolomé JM; Macdonald GJ; Steckler T; Jones CK; Niswender CM; Conn PJ; Lindsley CW; Stauffer SR; Daniels JS
    Drug Metab Dispos; 2013 Dec; 41(12):2066-75. PubMed ID: 24003250
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of Action of Panaxytriol on Midazolam 1'-Hydroxylation and 4-Hydroxylation Mediated by CYP3A in Liver Microsomes and Rat Primary Hepatocytes.
    He F; Zhang W; Zeng C; Xia C; Xiong Y; Zhang H; Huang S; Liu M
    Biol Pharm Bull; 2015; 38(10):1470-7. PubMed ID: 26424012
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential effect of Shenmai injection, a herbal preparation, on the cytochrome P450 3A-mediated 1'-hydroxylation and 4-hydroxylation of midazolam.
    Xia C; Sun J; Wang G; Shang L; Zhang X; Zhang R; Wang X; Hao H; Xie L
    Chem Biol Interact; 2009 Aug; 180(3):440-8. PubMed ID: 19557931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Midazolam oxidation by cytochrome P450 3A4 and active-site mutants: an evaluation of multiple binding sites and of the metabolic pathway that leads to enzyme inactivation.
    Khan KK; He YQ; Domanski TL; Halpert JR
    Mol Pharmacol; 2002 Mar; 61(3):495-506. PubMed ID: 11854429
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H; Nakajima M; Katoh M; Kanoh A; Tamura O; Ishibashi H; Yokoi T
    Drug Metab Dispos; 2005 Jan; 33(1):23-30. PubMed ID: 15470160
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N; Oda Y; Hase I; Asada A
    Br J Anaesth; 2001 Apr; 86(4):540-4. PubMed ID: 11573629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.
    Roberts AG; Yang J; Halpert JR; Nelson SD; Thummel KT; Atkins WM
    Biochemistry; 2011 Dec; 50(50):10804-18. PubMed ID: 21992114
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.