168 related articles for article (PubMed ID: 19371999)
1. Mdm4 loss in the intestinal epithelium leads to compartmentalized cell death but no tissue abnormalities.
Valentin-Vega YA; Box N; Terzian T; Lozano G
Differentiation; 2009 Jun; 77(5):442-9. PubMed ID: 19371999
[TBL] [Abstract][Full Text] [Related]
2. Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.
De Clercq S; Gembarska A; Denecker G; Maetens M; Naessens M; Haigh K; Haigh JJ; Marine JC
Mol Cell Biol; 2010 Nov; 30(22):5394-405. PubMed ID: 20855528
[TBL] [Abstract][Full Text] [Related]
3. Mouse models of Mdm2 and Mdm4 and their clinical implications.
Xiong S
Chin J Cancer; 2013 Jul; 32(7):371-5. PubMed ID: 23327795
[TBL] [Abstract][Full Text] [Related]
4. p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.
Tashakori M; Zhang Y; Xiong S; You MJ; Lozano G
Mol Cancer Res; 2016 Jan; 14(1):56-65. PubMed ID: 26527653
[TBL] [Abstract][Full Text] [Related]
5. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.
Xiong S; Van Pelt CS; Elizondo-Fraire AC; Liu G; Lozano G
Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3226-31. PubMed ID: 16492743
[TBL] [Abstract][Full Text] [Related]
6. Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity.
Bardot B; Bouarich-Bourimi R; Leemput J; Lejour V; Hamon A; Plancke L; Jochemsen AG; Simeonova I; Fang M; Toledo F
Oncogene; 2015 May; 34(22):2943-8. PubMed ID: 25088193
[TBL] [Abstract][Full Text] [Related]
7. Mdm2 and Mdm4 loss regulates distinct p53 activities.
Barboza JA; Iwakuma T; Terzian T; El-Naggar AK; Lozano G
Mol Cancer Res; 2008 Jun; 6(6):947-54. PubMed ID: 18567799
[TBL] [Abstract][Full Text] [Related]
8. Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.
Migliorini D; Lazzerini Denchi E; Danovi D; Jochemsen A; Capillo M; Gobbi A; Helin K; Pelicci PG; Marine JC
Mol Cell Biol; 2002 Aug; 22(15):5527-38. PubMed ID: 12101245
[TBL] [Abstract][Full Text] [Related]
9. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
Parant J; Chavez-Reyes A; Little NA; Yan W; Reinke V; Jochemsen AG; Lozano G
Nat Genet; 2001 Sep; 29(1):92-5. PubMed ID: 11528400
[TBL] [Abstract][Full Text] [Related]
10. MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response.
Mancini F; Pieroni L; Monteleone V; LucĂ R; Fici L; Luca E; Urbani A; Xiong S; Soddu S; Masetti R; Lozano G; Pontecorvi A; Moretti F
Oncogene; 2016 Jan; 35(2):228-40. PubMed ID: 25961923
[TBL] [Abstract][Full Text] [Related]
11. Spontaneous tumorigenesis in mice overexpressing the p53-negative regulator Mdm4.
Xiong S; Pant V; Suh YA; Van Pelt CS; Wang Y; Valentin-Vega YA; Post SM; Lozano G
Cancer Res; 2010 Sep; 70(18):7148-54. PubMed ID: 20736370
[TBL] [Abstract][Full Text] [Related]
12. Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.
Francoz S; Froment P; Bogaerts S; De Clercq S; Maetens M; Doumont G; Bellefroid E; Marine JC
Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3232-7. PubMed ID: 16492744
[TBL] [Abstract][Full Text] [Related]
13. The p53 inhibitor Mdm4 cooperates with multiple genetic lesions in tumourigenesis.
Xiong S; Pant V; Zhang Y; Aryal NK; You MJ; Kusewitt D; Lozano G
J Pathol; 2017 Mar; 241(4):501-510. PubMed ID: 27925213
[TBL] [Abstract][Full Text] [Related]
14. Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.
Grier JD; Xiong S; Elizondo-Fraire AC; Parant JM; Lozano G
Mol Cell Biol; 2006 Jan; 26(1):192-8. PubMed ID: 16354690
[TBL] [Abstract][Full Text] [Related]
15. Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
Boesten LS; Zadelaar SM; De Clercq S; Francoz S; van Nieuwkoop A; Biessen EA; Hofmann F; Feil S; Feil R; Jochemsen AG; Zurcher C; Havekes LM; van Vlijmen BJ; Marine JC
Cell Death Differ; 2006 Dec; 13(12):2089-98. PubMed ID: 16729027
[TBL] [Abstract][Full Text] [Related]
16. Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
Iwakuma T; Parant JM; Fasulo M; Zwart E; Jacks T; de Vries A; Lozano G
Oncogene; 2004 Oct; 23(46):7644-50. PubMed ID: 15361844
[TBL] [Abstract][Full Text] [Related]
17. Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development.
Zhang Q; He X; Chen L; Zhang C; Gao X; Yang Z; Liu G
J Pathol; 2012 Nov; 228(3):416-28. PubMed ID: 22821713
[TBL] [Abstract][Full Text] [Related]
18. Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival.
Fang M; Simeonova I; Bardot B; Lejour V; Jaber S; Bouarich-Bourimi R; Morin A; Toledo F
Oncogene; 2014 Mar; 33(10):1336-9. PubMed ID: 23474762
[TBL] [Abstract][Full Text] [Related]
19. Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
Chavez-Reyes A; Parant JM; Amelse LL; de Oca Luna RM; Korsmeyer SJ; Lozano G
Cancer Res; 2003 Dec; 63(24):8664-9. PubMed ID: 14695178
[TBL] [Abstract][Full Text] [Related]
20. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
Toledo F; Krummel KA; Lee CJ; Liu CW; Rodewald LW; Tang M; Wahl GM
Cancer Cell; 2006 Apr; 9(4):273-85. PubMed ID: 16616333
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]