730 related articles for article (PubMed ID: 19374402)
1. Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening.
Klabunde T; Giegerich C; Evers A
J Med Chem; 2009 May; 52(9):2923-32. PubMed ID: 19374402
[TBL] [Abstract][Full Text] [Related]
2. An automated system for the analysis of G protein-coupled receptor transmembrane binding pockets: alignment, receptor-based pharmacophores, and their application.
Kratochwil NA; Malherbe P; Lindemann L; Ebeling M; Hoener MC; Mühlemann A; Porter RH; Stahl M; Gerber PR
J Chem Inf Model; 2005; 45(5):1324-36. PubMed ID: 16180909
[TBL] [Abstract][Full Text] [Related]
3. PREDICT modeling and in-silico screening for G-protein coupled receptors.
Shacham S; Marantz Y; Bar-Haim S; Kalid O; Warshaviak D; Avisar N; Inbal B; Heifetz A; Fichman M; Topf M; Naor Z; Noiman S; Becker OM
Proteins; 2004 Oct; 57(1):51-86. PubMed ID: 15326594
[TBL] [Abstract][Full Text] [Related]
4. Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.
Evers A; Hessler G; Matter H; Klabunde T
J Med Chem; 2005 Aug; 48(17):5448-65. PubMed ID: 16107144
[TBL] [Abstract][Full Text] [Related]
5. Drug design strategies for targeting G-protein-coupled receptors.
Klabunde T; Hessler G
Chembiochem; 2002 Oct; 3(10):928-44. PubMed ID: 12362358
[TBL] [Abstract][Full Text] [Related]
6. Protein-based virtual screening of chemical databases. II. Are homology models of G-Protein Coupled Receptors suitable targets?
Bissantz C; Bernard P; Hibert M; Rognan D
Proteins; 2003 Jan; 50(1):5-25. PubMed ID: 12471595
[TBL] [Abstract][Full Text] [Related]
7. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function.
Kristiansen K
Pharmacol Ther; 2004 Jul; 103(1):21-80. PubMed ID: 15251227
[TBL] [Abstract][Full Text] [Related]
8. Virtual screen for ligands of orphan G protein-coupled receptors.
Bock JR; Gough DA
J Chem Inf Model; 2005; 45(5):1402-14. PubMed ID: 16180917
[TBL] [Abstract][Full Text] [Related]
9. Homology model-based virtual screening for GPCR ligands using docking and target-biased scoring.
Radestock S; Weil T; Renner S
J Chem Inf Model; 2008 May; 48(5):1104-17. PubMed ID: 18442221
[TBL] [Abstract][Full Text] [Related]
10. Snooker: a structure-based pharmacophore generation tool applied to class A GPCRs.
Sanders MP; Verhoeven S; de Graaf C; Roumen L; Vroling B; Nabuurs SB; de Vlieg J; Klomp JP
J Chem Inf Model; 2011 Sep; 51(9):2277-92. PubMed ID: 21866955
[TBL] [Abstract][Full Text] [Related]
11. Recognition of privileged structures by G-protein coupled receptors.
Bondensgaard K; Ankersen M; Thøgersen H; Hansen BS; Wulff BS; Bywater RP
J Med Chem; 2004 Feb; 47(4):888-99. PubMed ID: 14761190
[TBL] [Abstract][Full Text] [Related]
12. Modeling small molecule-compound binding to G-protein-coupled receptors.
Vaidehi N; Pease JE; Horuk R
Methods Enzymol; 2009; 460():263-88. PubMed ID: 19446730
[TBL] [Abstract][Full Text] [Related]
13. High-throughput modeling of human G-protein coupled receptors: amino acid sequence alignment, three-dimensional model building, and receptor library screening.
Bissantz C; Logean A; Rognan D
J Chem Inf Comput Sci; 2004; 44(3):1162-76. PubMed ID: 15154786
[TBL] [Abstract][Full Text] [Related]
14. Homology modeling of G-protein-coupled receptors with X-ray structures on the rise.
Yarnitzky T; Levit A; Niv MY
Curr Opin Drug Discov Devel; 2010 May; 13(3):317-25. PubMed ID: 20443165
[TBL] [Abstract][Full Text] [Related]
15. Three-dimensional model of the human urotensin-II receptor: docking of human urotensin-II and nonpeptide antagonists in the binding site and comparison with an antagonist pharmacophore model.
Lescot E; Sopkova-de Oliveira Santos J; Colloc'h N; Rodrigo J; Milazzo-Segalas I; Bureau R; Rault S
Proteins; 2008 Oct; 73(1):173-84. PubMed ID: 18409194
[TBL] [Abstract][Full Text] [Related]
16. Fuzzy pharmacophore models from molecular alignments for correlation-vector-based virtual screening.
Renner S; Schneider G
J Med Chem; 2004 Sep; 47(19):4653-64. PubMed ID: 15341481
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
Huber T; Menon S; Sakmar TP
Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
[TBL] [Abstract][Full Text] [Related]
18. Ligand-steered modeling and docking: A benchmarking study in class A G-protein-coupled receptors.
Phatak SS; Gatica EA; Cavasotto CN
J Chem Inf Model; 2010 Dec; 50(12):2119-28. PubMed ID: 21080692
[TBL] [Abstract][Full Text] [Related]
19. Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor.
Miller LJ; Dong M; Harikumar KG; Gao F
Biochem Soc Trans; 2007 Aug; 35(Pt 4):709-12. PubMed ID: 17635130
[TBL] [Abstract][Full Text] [Related]
20. Molecular modeling of the second extracellular loop of G-protein coupled receptors and its implication on structure-based virtual screening.
de Graaf C; Foata N; Engkvist O; Rognan D
Proteins; 2008 May; 71(2):599-620. PubMed ID: 17972285
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]