BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

644 related articles for article (PubMed ID: 19376776)

  • 1. Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression.
    Wang C; Qi R; Li N; Wang Z; An H; Zhang Q; Yu Y; Cao X
    J Biol Chem; 2009 Jun; 284(24):16183-16190. PubMed ID: 19376776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation.
    Kim JY; Kim EH; Park SS; Lim JH; Kwon TK; Choi KS
    J Cell Biochem; 2008 Dec; 105(6):1386-98. PubMed ID: 18980244
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway.
    Inoue T; Shiraki K; Fuke H; Yamanaka Y; Miyashita K; Yamaguchi Y; Yamamoto N; Ito K; Sugimoto K; Nakano T
    Anticancer Drugs; 2006 Mar; 17(3):261-8. PubMed ID: 16520654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bortezomib overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells in part through the inhibition of the phosphatidylinositol 3-kinase/Akt pathway.
    Chen KF; Yeh PY; Hsu C; Hsu CH; Lu YS; Hsieh HP; Chen PJ; Cheng AL
    J Biol Chem; 2009 Apr; 284(17):11121-33. PubMed ID: 19261616
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis.
    Pellerito O; Calvaruso G; Portanova P; De Blasio A; Santulli A; Vento R; Tesoriere G; Giuliano M
    Mol Pharmacol; 2010 May; 77(5):854-63. PubMed ID: 20159939
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.
    Qi R; An H; Yu Y; Zhang M; Liu S; Xu H; Guo Z; Cheng T; Cao X
    Cancer Res; 2003 Dec; 63(23):8323-9. PubMed ID: 14678992
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 6-Methoxydihydrosanguinarine exhibits cytotoxicity and sensitizes TRAIL-induced apoptosis of hepatocellular carcinoma cells through ROS-mediated upregulation of DR5.
    Wang LL; Li RT; Zang ZH; Song YX; Zhang YZ; Zhang TF; Wang FZ; Hao GP; Cao L
    Med Oncol; 2023 Aug; 40(9):266. PubMed ID: 37566135
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triptolide sensitizes TRAIL-induced apoptosis in prostate cancer cells via p53-mediated DR5 up-regulation.
    Xiaowen H; Yi S
    Mol Biol Rep; 2012 Sep; 39(9):8763-70. PubMed ID: 22707197
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
    Ganten TM; Haas TL; Sykora J; Stahl H; Sprick MR; Fas SC; Krueger A; Weigand MA; Grosse-Wilde A; Stremmel W; Krammer PH; Walczak H
    Cell Death Differ; 2004 Jul; 11 Suppl 1():S86-96. PubMed ID: 15105837
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells.
    Yang JF; Cao JG; Tian L; Liu F
    Cancer Chemother Pharmacol; 2012 Jan; 69(1):195-206. PubMed ID: 21660448
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wogonin and related natural flavones overcome tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein resistance of tumors by down-regulation of c-FLIP protein and up-regulation of TRAIL receptor 2 expression.
    Ding J; Polier G; Köhler R; Giaisi M; Krammer PH; Li-Weber M
    J Biol Chem; 2012 Jan; 287(1):641-649. PubMed ID: 22086925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Azadirone, a limonoid tetranortriterpene, induces death receptors and sensitizes human cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through a p53 protein-independent mechanism: evidence for the role of the ROS-ERK-CHOP-death receptor pathway.
    Gupta SC; Francis SK; Nair MS; Mo YY; Aggarwal BB
    J Biol Chem; 2013 Nov; 288(45):32343-32356. PubMed ID: 24078627
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of apoptosis by pectenotoxin-2 is mediated with the induction of DR4/DR5, Egr-1 and NAG-1, activation of caspases and modulation of the Bcl-2 family in p53-deficient Hep3B hepatocellular carcinoma cells.
    Shin DY; Kim GY; Kim ND; Jung JH; Kim SK; Kang HS; Choi YH
    Oncol Rep; 2008 Feb; 19(2):517-26. PubMed ID: 18202802
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-κB pathway.
    Wan Z; Pan H; Liu S; Zhu J; Qi W; Fu K; Zhao T; Liang J
    Oncol Rep; 2015 Mar; 33(3):1560-6. PubMed ID: 25607597
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TRAIL-induced apoptosis of hepatocellular carcinoma cells is augmented by targeted therapies.
    Koehler BC; Urbanik T; Vick B; Boger RJ; Heeger S; Galle PR; Schuchmann M; Schulze-Bergkamen H
    World J Gastroenterol; 2009 Dec; 15(47):5924-35. PubMed ID: 20014456
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interferon-alpha sensitizes human hepatoma cells to TRAIL-induced apoptosis through DR5 upregulation and NF-kappa B inactivation.
    Shigeno M; Nakao K; Ichikawa T; Suzuki K; Kawakami A; Abiru S; Miyazoe S; Nakagawa Y; Ishikawa H; Hamasaki K; Nakata K; Ishii N; Eguchi K
    Oncogene; 2003 Mar; 22(11):1653-62. PubMed ID: 12642868
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant hepatoma cells to TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of DR5.
    Kim H; Kim EH; Eom YW; Kim WH; Kwon TK; Lee SJ; Choi KS
    Cancer Res; 2006 Feb; 66(3):1740-50. PubMed ID: 16452234
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs.
    Jayasooriya RG; Choi YH; Hyun JW; Kim GY
    Environ Toxicol Pharmacol; 2014 Nov; 38(3):959-67. PubMed ID: 25461556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF; Chen HL; Liu CY; Tai WT; Ichikawa K; Chen PJ; Cheng AL
    Biochem Pharmacol; 2012 Mar; 83(6):769-77. PubMed ID: 22230479
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sensitization of TRAIL-induced cell death by 20(S)-ginsenoside Rg3 via CHOP-mediated DR5 upregulation in human hepatocellular carcinoma cells.
    Lee JY; Jung KH; Morgan MJ; Kang YR; Lee HS; Koo GB; Hong SS; Kwon SW; Kim YS
    Mol Cancer Ther; 2013 Mar; 12(3):274-85. PubMed ID: 23053497
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.