BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

756 related articles for article (PubMed ID: 19379833)

  • 1. How to assess the mutagenic potential of cosmetic products without animal tests?
    Speit G
    Mutat Res; 2009 Aug; 678(2):108-12. PubMed ID: 19379833
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.
    Kirkland DJ; Henderson L; Marzin D; Müller L; Parry JM; Speit G; Tweats DJ; Williams GM
    Mutat Res; 2005 Dec; 588(2):88-105. PubMed ID: 16326131
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: genotoxicity. A COLIPA analysis.
    Pfuhler S; Kirst A; Aardema M; Banduhn N; Goebel C; Araki D; Costabel-Farkas M; Dufour E; Fautz R; Harvey J; Hewitt NJ; Hibatallah J; Carmichael P; Macfarlane M; Reisinger K; Rowland J; Schellauf F; Schepky A; Scheel J
    Regul Toxicol Pharmacol; 2010; 57(2-3):315-24. PubMed ID: 20382194
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Determination of genetic toxicity and potential carcinogenicity in vitro--challenges post the Seventh Amendment to the European Cosmetics Directive.
    Tweats DJ; Scott AD; Westmoreland C; Carmichael PL
    Mutagenesis; 2007 Jan; 22(1):5-13. PubMed ID: 17142828
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity.
    Kirkland D; Aardema M; Henderson L; Müller L
    Mutat Res; 2005 Jul; 584(1-2):1-256. PubMed ID: 15979392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.
    Thybaud V; Aardema M; Clements J; Dearfield K; Galloway S; Hayashi M; Jacobson-Kram D; Kirkland D; MacGregor JT; Marzin D; Ohyama W; Schuler M; Suzuki H; Zeiger E;
    Mutat Res; 2007 Feb; 627(1):41-58. PubMed ID: 17126066
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.
    Kirkland DJ; Aardema M; Banduhn N; Carmichael P; Fautz R; Meunier JR; Pfuhler S
    Mutagenesis; 2007 May; 22(3):161-75. PubMed ID: 17369606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Strategy for genotoxicity testing--metabolic considerations.
    Ku WW; Bigger A; Brambilla G; Glatt H; Gocke E; Guzzie PJ; Hakura A; Honma M; Martus HJ; Obach RS; Roberts S;
    Mutat Res; 2007 Feb; 627(1):59-77. PubMed ID: 17141553
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000-12).
    Ates G; Doktorova TY; Pauwels M; Rogiers V
    Mutagenesis; 2014 Mar; 29(2):115-21. PubMed ID: 24435663
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Further development of the EpiDerm 3D reconstructed human skin micronucleus (RSMN) assay.
    Mun GC; Aardema MJ; Hu T; Barnett B; Kaluzhny Y; Klausner M; Karetsky V; Dahl EL; Curren RD
    Mutat Res; 2009 Mar; 673(2):92-9. PubMed ID: 19167515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Application of in vitro cell transformation assays in regulatory toxicology for pharmaceuticals, chemicals, food products and cosmetics.
    Vanparys P; Corvi R; Aardema MJ; Gribaldo L; Hayashi M; Hoffmann S; Schechtman L
    Mutat Res; 2012 Apr; 744(1):111-6. PubMed ID: 22342612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH).
    Lilienblum W; Dekant W; Foth H; Gebel T; Hengstler JG; Kahl R; Kramer PJ; Schweinfurth H; Wollin KM
    Arch Toxicol; 2008 Apr; 82(4):211-36. PubMed ID: 18322675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Way forward in case of a false positive in vitro genotoxicity result for a cosmetic substance?
    Doktorova TY; Ates G; Vinken M; Vanhaecke T; Rogiers V
    Toxicol In Vitro; 2014 Feb; 28(1):54-9. PubMed ID: 24095862
    [TBL] [Abstract][Full Text] [Related]  

  • 15. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
    Kirkland D; Pfuhler S; Tweats D; Aardema M; Corvi R; Darroudi F; Elhajouji A; Glatt H; Hastwell P; Hayashi M; Kasper P; Kirchner S; Lynch A; Marzin D; Maurici D; Meunier JR; Müller L; Nohynek G; Parry J; Parry E; Thybaud V; Tice R; van Benthem J; Vanparys P; White P
    Mutat Res; 2007 Mar; 628(1):31-55. PubMed ID: 17293159
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Cosmetics Europe strategy for animal-free genotoxicity testing: project status up-date.
    Pfuhler S; Fautz R; Ouedraogo G; Latil A; Kenny J; Moore C; Diembeck W; Hewitt NJ; Reisinger K; Barroso J
    Toxicol In Vitro; 2014 Feb; 28(1):18-23. PubMed ID: 23811264
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Follow-up actions from positive results of in vitro genetic toxicity testing.
    Dearfield KL; Thybaud V; Cimino MC; Custer L; Czich A; Harvey JS; Hester S; Kim JH; Kirkland D; Levy DD; Lorge E; Moore MM; Ouédraogo-Arras G; Schuler M; Suter W; Sweder K; Tarlo K; van Benthem J; van Goethem F; Witt KL
    Environ Mol Mutagen; 2011 Apr; 52(3):177-204. PubMed ID: 20963811
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles.
    Kirkland D; Aardema M; Müller L; Makoto H
    Mutat Res; 2006 Sep; 608(1):29-42. PubMed ID: 16769241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Final report on the safety assessment of capsicum annuum extract, capsicum annuum fruit extract, capsicum annuum resin, capsicum annuum fruit powder, capsicum frutescens fruit, capsicum frutescens fruit extract, capsicum frutescens resin, and capsaicin.
    Int J Toxicol; 2007; 26 Suppl 1():3-106. PubMed ID: 17365137
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development.
    Westerink WM; Stevenson JC; Horbach GJ; Schoonen WG
    Mutat Res; 2010 Feb; 696(1):21-40. PubMed ID: 20006733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.