238 related articles for article (PubMed ID: 19383288)
1. Mice thrive without Cdk4 and Cdk2.
Barrière C; Santamaría D; Cerqueira A; Galán J; Martín A; Ortega S; Malumbres M; Dubus P; Barbacid M
Mol Oncol; 2007 Jun; 1(1):72-83. PubMed ID: 19383288
[TBL] [Abstract][Full Text] [Related]
2. Cdk2 and Cdk4 activities are dispensable for tumorigenesis caused by the loss of p53.
Padmakumar VC; Aleem E; Berthet C; Hilton MB; Kaldis P
Mol Cell Biol; 2009 May; 29(10):2582-93. PubMed ID: 19307310
[TBL] [Abstract][Full Text] [Related]
3. Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells.
Kang J; Sergio CM; Sutherland RL; Musgrove EA
BMC Cancer; 2014 Jan; 14():32. PubMed ID: 24444383
[TBL] [Abstract][Full Text] [Related]
4. CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point.
Bisteau X; Paternot S; Colleoni B; Ecker K; Coulonval K; De Groote P; Declercq W; Hengst L; Roger PP
PLoS Genet; 2013 May; 9(5):e1003546. PubMed ID: 23737759
[TBL] [Abstract][Full Text] [Related]
5. MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.
Gillam MP; Nimbalkar D; Sun L; Christov K; Ray D; Kaldis P; Liu X; Kiyokawa H
Oncogene; 2015 Feb; 34(7):932-8. PubMed ID: 24531709
[TBL] [Abstract][Full Text] [Related]
6. A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression.
Schachter MM; Merrick KA; Larochelle S; Hirschi A; Zhang C; Shokat KM; Rubin SM; Fisher RP
Mol Cell; 2013 Apr; 50(2):250-60. PubMed ID: 23622515
[TBL] [Abstract][Full Text] [Related]
7. Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress.
Jayapal SR; Wang CQ; Bisteau X; Caldez MJ; Lim S; Tergaonkar V; Osato M; Kaldis P
Haematologica; 2015 Apr; 100(4):431-8. PubMed ID: 25616574
[TBL] [Abstract][Full Text] [Related]
8. Characterization of murine gammaherpesvirus 68 v-cyclin interactions with cellular cdks.
Upton JW; van Dyk LF; Speck SH
Virology; 2005 Oct; 341(2):271-83. PubMed ID: 16102793
[TBL] [Abstract][Full Text] [Related]
9. Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition.
Li W; Kotoshiba S; Berthet C; Hilton MB; Kaldis P
Proc Natl Acad Sci U S A; 2009 Jan; 106(2):486-91. PubMed ID: 19129496
[TBL] [Abstract][Full Text] [Related]
10. Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
Adon AM; Zeng X; Harrison MK; Sannem S; Kiyokawa H; Kaldis P; Saavedra HI
Mol Cell Biol; 2010 Feb; 30(3):694-710. PubMed ID: 19933848
[TBL] [Abstract][Full Text] [Related]
11. Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2.
Pack LR; Daigh LH; Chung M; Meyer T
Nat Commun; 2021 Jun; 12(1):3356. PubMed ID: 34099663
[TBL] [Abstract][Full Text] [Related]
12. Cdk1, but not Cdk2, is the sole Cdk that is essential and sufficient to drive resumption of meiosis in mouse oocytes.
Adhikari D; Zheng W; Shen Y; Gorre N; Ning Y; Halet G; Kaldis P; Liu K
Hum Mol Genet; 2012 Jun; 21(11):2476-84. PubMed ID: 22367880
[TBL] [Abstract][Full Text] [Related]
13. Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.
Prall OW; Sarcevic B; Musgrove EA; Watts CK; Sutherland RL
J Biol Chem; 1997 Apr; 272(16):10882-94. PubMed ID: 9099745
[TBL] [Abstract][Full Text] [Related]
14. Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.
Hsieh FF; Barnett LA; Green WF; Freedman K; Matushansky I; Skoultchi AI; Kelley LL
Blood; 2000 Oct; 96(8):2746-54. PubMed ID: 11023508
[TBL] [Abstract][Full Text] [Related]
15. Expression of cyclin E renders cyclin D-CDK4 dispensable for inactivation of the retinoblastoma tumor suppressor protein, activation of E2F, and G1-S phase progression.
Keenan SM; Lents NH; Baldassare JJ
J Biol Chem; 2004 Feb; 279(7):5387-96. PubMed ID: 14645251
[TBL] [Abstract][Full Text] [Related]
16. A confederacy of kinases: Cdk2 and Cdk4 conspire to control embryonic cell proliferation.
Hinds PW
Mol Cell; 2006 May; 22(4):432-3. PubMed ID: 16713571
[TBL] [Abstract][Full Text] [Related]
17. S-phase lengthening induced by p16(INK4a) overexpression in malignant cells with wild-type pRb and p53.
Chien WW; Domenech C; Catallo R; Salles G; Ffrench M
Cell Cycle; 2010 Aug; 9(16):3286-96. PubMed ID: 20703084
[TBL] [Abstract][Full Text] [Related]
18. Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation.
Yang HW; Cappell SD; Jaimovich A; Liu C; Chung M; Daigh LH; Pack LR; Fan Y; Regot S; Covert M; Meyer T
Elife; 2020 Apr; 9():. PubMed ID: 32255427
[TBL] [Abstract][Full Text] [Related]
19. Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6.
Malumbres M; Sotillo R; Santamaría D; Galán J; Cerezo A; Ortega S; Dubus P; Barbacid M
Cell; 2004 Aug; 118(4):493-504. PubMed ID: 15315761
[TBL] [Abstract][Full Text] [Related]
20. Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation.
Berthet C; Klarmann KD; Hilton MB; Suh HC; Keller JR; Kiyokawa H; Kaldis P
Dev Cell; 2006 May; 10(5):563-73. PubMed ID: 16678773
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
