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6. A structure-based analysis of huntingtin mutant polyglutamine aggregation and toxicity: evidence for a compact beta-sheet structure. Poirier MA; Jiang H; Ross CA Hum Mol Genet; 2005 Mar; 14(6):765-74. PubMed ID: 15689354 [TBL] [Abstract][Full Text] [Related]
7. Selection of behaviors and segmental coordination during larval locomotion is disrupted by nuclear polyglutamine inclusions in a new Drosophila Huntington's disease-like model. Nishimura Y; Yalgin C; Akimoto S; Doumanis J; Sasajima R; Nukina N; Miyakawa H; Moore AW; Morimoto T J Neurogenet; 2010 Dec; 24(4):194-206. PubMed ID: 21087194 [TBL] [Abstract][Full Text] [Related]
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11. Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation. Zucchelli S; Marcuzzi F; Codrich M; Agostoni E; Vilotti S; Biagioli M; Pinto M; Carnemolla A; Santoro C; Gustincich S; Persichetti F J Biol Chem; 2011 Jul; 286(28):25108-17. PubMed ID: 21454471 [TBL] [Abstract][Full Text] [Related]
12. Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice. Schilling G; Savonenko AV; Klevytska A; Morton JL; Tucker SM; Poirier M; Gale A; Chan N; Gonzales V; Slunt HH; Coonfield ML; Jenkins NA; Copeland NG; Ross CA; Borchelt DR Hum Mol Genet; 2004 Aug; 13(15):1599-610. PubMed ID: 15190011 [TBL] [Abstract][Full Text] [Related]
13. Mutant huntingtin promotes the fibrillogenesis of wild-type huntingtin: a potential mechanism for loss of huntingtin function in Huntington's disease. Busch A; Engemann S; Lurz R; Okazawa H; Lehrach H; Wanker EE J Biol Chem; 2003 Oct; 278(42):41452-61. PubMed ID: 12888569 [TBL] [Abstract][Full Text] [Related]
14. Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice. Zheng S; Clabough EB; Sarkar S; Futter M; Rubinsztein DC; Zeitlin SO PLoS Genet; 2010 Feb; 6(2):e1000838. PubMed ID: 20140187 [TBL] [Abstract][Full Text] [Related]
15. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease. Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655 [TBL] [Abstract][Full Text] [Related]
16. Effects of overexpression of huntingtin proteins on mitochondrial integrity. Wang H; Lim PJ; Karbowski M; Monteiro MJ Hum Mol Genet; 2009 Feb; 18(4):737-52. PubMed ID: 19039036 [TBL] [Abstract][Full Text] [Related]
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19. Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA. Wang YL; Liu W; Wada E; Murata M; Wada K; Kanazawa I Neurosci Res; 2005 Nov; 53(3):241-9. PubMed ID: 16095740 [TBL] [Abstract][Full Text] [Related]