BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 19402667)

  • 1. Synthesis and biophysical characterization of chlorambucil anticancer ether lipid prodrugs.
    Pedersen PJ; Christensen MS; Ruysschaert T; Linderoth L; Andresen TL; Melander F; Mouritsen OG; Madsen R; Clausen MH
    J Med Chem; 2009 May; 52(10):3408-15. PubMed ID: 19402667
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Liposomal formulation of retinoids designed for enzyme triggered release.
    Pedersen PJ; Adolph SK; Subramanian AK; Arouri A; Andresen TL; Mouritsen OG; Madsen R; Madsen MW; Peters GH; Clausen MH
    J Med Chem; 2010 May; 53(9):3782-92. PubMed ID: 20405849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decreased cytotoxicity and increased antimitotic activity of a proline analogue of chlorambucil as a prodrug susceptible to the action of fibroblast's prolidase.
    Bielawska A; Chrzanowski K; Bielawski K; Pałka J
    Pharmazie; 2001 Apr; 56(4):290-4. PubMed ID: 11338665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and in vitro efficacy of transferrin conjugates of the anticancer drug chlorambucil.
    Beyer U; Roth T; Schumacher P; Maier G; Unold A; Frahm AW; Fiebig HH; Unger C; Kratz F
    J Med Chem; 1998 Jul; 41(15):2701-8. PubMed ID: 9667961
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Two novel nucleoside ester derivatives of chlorambucil as potential antileukemic prodrugs: a preliminary study.
    Kryczka T; Kazimierczuk Z; Kozłowska M; Chrapusta SJ; Vilpo L; Vilpo J; Stachnik K; Janisz M; Grieb P
    Anticancer Drugs; 2007 Mar; 18(3):301-10. PubMed ID: 17264763
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phospholipase A(2)-susceptible liposomes of anticancer double lipid-prodrugs.
    Arouri A; Mouritsen OG
    Eur J Pharm Sci; 2012 Mar; 45(4):408-20. PubMed ID: 21946258
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enzymatic release of antitumor ether lipids by specific phospholipase A2 activation of liposome-forming prodrugs.
    Andresen TL; Davidsen J; Begtrup M; Mouritsen OG; Jørgensen K
    J Med Chem; 2004 Mar; 47(7):1694-703. PubMed ID: 15027860
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Self-immolative nitrogen mustard prodrugs for suicide gene therapy.
    Niculescu-Duvaz D; Niculescu-Duvaz I; Friedlos F; Martin J; Spooner R; Davies L; Marais R; Springer CJ
    J Med Chem; 1998 Dec; 41(26):5297-309. PubMed ID: 9857097
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Small-molecule based delivery systems for alkylating antineoplastic compounds.
    Bielawski K; Bielawska A
    ChemMedChem; 2008 Apr; 3(4):536-42. PubMed ID: 18157855
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer.
    Zhao RY; Erickson HK; Leece BA; Reid EE; Goldmacher VS; Lambert JM; Chari RV
    J Med Chem; 2012 Jan; 55(2):766-82. PubMed ID: 22148292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. To determine the cytotoxicity of chlorambucil and one of its nitro-derivatives, conjugated to prasterone and pregnenolone, towards eight human cancer cell-lines.
    Shervington LA; Smith N; Norman E; Ward T; Phillips R; Shervington A
    Eur J Med Chem; 2009 Jul; 44(7):2944-51. PubMed ID: 19121874
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of a prodrug designed to release multiple inhibitors of the epidermal growth factor receptor tyrosine kinase and an alkylating agent: a novel tumor targeting concept.
    Banerjee R; Rachid Z; McNamee J; Jean-Claude BJ
    J Med Chem; 2003 Dec; 46(25):5546-51. PubMed ID: 14640561
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Decreased cytotoxicity and increased antimitotic activity of proline analogue of chlorambucil as a prodrug in breast cancer MCF-7 cells.
    Bielawska A; Chrzanowski K; Bielawski K; Pałka J
    Acta Pol Pharm; 2000 Nov; 57 Suppl():103-5. PubMed ID: 11293233
    [No Abstract]   [Full Text] [Related]  

  • 14. Structure-activity relationships for 4-nitrobenzyl carbamates of 5-aminobenz[e]indoline minor groove alkylating agents as prodrugs for GDEPT in conjunction with E. coli nitroreductase.
    Hay MP; Atwell GJ; Wilson WR; Pullen SM; Denny WA
    J Med Chem; 2003 Jun; 46(12):2456-66. PubMed ID: 12773049
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prolidase as a prodrug converting enzyme I. Synthesis of proline analogue of chlorambucil and its susceptibility to the action of prolidase.
    Bielawska A; Bielawski K; Pałka J
    Rocz Akad Med Bialymst; 1997; 42(1):148-55. PubMed ID: 9581474
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thermoresponsive chlorambucil derivatives for tumour targeting.
    Clavel CM; Zava O; Schmitt F; Kenzaoui BH; Nazarov AA; Juillerat-Jeanneret L; Dyson PJ
    Angew Chem Int Ed Engl; 2011 Jul; 50(31):7124-7. PubMed ID: 21688360
    [No Abstract]   [Full Text] [Related]  

  • 17. Mechanistic study of the sPLA2-mediated hydrolysis of a thio-ester pro anticancer ether lipid.
    Linderoth L; Fristrup P; Hansen M; Melander F; Madsen R; Andresen TL; Peters GH
    J Am Chem Soc; 2009 Sep; 131(34):12193-200. PubMed ID: 19663381
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of new cyclic amidine analogs of chlorambucil.
    Bielawska A; Bielawski K; Muszyńska A
    Farmaco; 2004 Feb; 59(2):111-7. PubMed ID: 14871502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An improved synthesis of lysosomal activated mustard prodrug for tumor-specific activation and its cytotoxic evaluation.
    Adidala R; Devalapally H; Srivari C; Devarakonda R K; Akkinepally RR
    Drug Dev Ind Pharm; 2012 Sep; 38(9):1047-53. PubMed ID: 22185667
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-activity relationships for 2,4-dinitrobenzamide-5-mustards as prodrugs for the Escherichia coli nfsB nitroreductase in gene therapy.
    Atwell GJ; Yang S; Pruijn FB; Pullen SM; Hogg A; Patterson AV; Wilson WR; Denny WA
    J Med Chem; 2007 Mar; 50(6):1197-212. PubMed ID: 17326614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.