BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 19403684)

  • 1. Human immunodeficiency virus type 1 Nef protein targets CD4 to the multivesicular body pathway.
    daSilva LL; Sougrat R; Burgos PV; Janvier K; Mattera R; Bonifacino JS
    J Virol; 2009 Jul; 83(13):6578-90. PubMed ID: 19403684
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction of HIV-1 Nef protein with the host protein Alix promotes lysosomal targeting of CD4 receptor.
    Amorim NA; da Silva EM; de Castro RO; da Silva-Januário ME; Mendonça LM; Bonifacino JS; da Costa LJ; daSilva LL
    J Biol Chem; 2014 Oct; 289(40):27744-56. PubMed ID: 25118280
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CD4 downregulation by the HIV-1 protein Nef reveals distinct roles for the γ1 and γ2 subunits of the AP-1 complex in protein trafficking.
    Tavares LA; da Silva EM; da Silva-Januário ME; Januário YC; de Cavalho JV; Czernisz ÉS; Mardones GA; daSilva LL
    J Cell Sci; 2017 Jan; 130(2):429-443. PubMed ID: 27909244
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System.
    Shi J; Xiong R; Zhou T; Su P; Zhang X; Qiu X; Li H; Li S; Yu C; Wang B; Ding C; Smithgall TE; Zheng YH
    J Virol; 2018 Jun; 92(11):. PubMed ID: 29514909
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes.
    Piguet V; Gu F; Foti M; Demaurex N; Gruenberg J; Carpentier JL; Trono D
    Cell; 1999 Apr; 97(1):63-73. PubMed ID: 10199403
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation.
    Jin YJ; Cai CY; Zhang X; Burakoff SJ
    J Immunol; 2008 Jun; 180(12):7878-86. PubMed ID: 18523251
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Down-regulation of CTLA-4 by HIV-1 Nef protein.
    El-Far M; Isabelle C; Chomont N; Bourbonnière M; Fonseca S; Ancuta P; Peretz Y; Chouikh Y; Halwani R; Schwartz O; Madrenas J; Freeman GJ; Routy JP; Haddad EK; Sékaly RP
    PLoS One; 2013; 8(1):e54295. PubMed ID: 23372701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two Functional Variants of AP-1 Complexes Composed of either γ2 or γ1 Subunits Are Independently Required for Major Histocompatibility Complex Class I Downregulation by HIV-1 Nef.
    Tavares LA; de Carvalho JV; Costa CS; Silveira RM; de Carvalho AN; Donadi EA; daSilva LLP
    J Virol; 2020 Mar; 94(7):. PubMed ID: 31915283
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.
    Rose JJ; Janvier K; Chandrasekhar S; Sekaly RP; Bonifacino JS; Venkatesan S
    J Biol Chem; 2005 Mar; 280(9):7413-26. PubMed ID: 15611114
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.
    Chaudhuri R; Lindwasser OW; Smith WJ; Hurley JH; Bonifacino JS
    J Virol; 2007 Apr; 81(8):3877-90. PubMed ID: 17267500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.
    Bresnahan PA; Yonemoto W; Ferrell S; Williams-Herman D; Geleziunas R; Greene WC
    Curr Biol; 1998 Nov; 8(22):1235-8. PubMed ID: 9811606
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes.
    Schwartz O; Dautry-Varsat A; Goud B; Maréchal V; Subtil A; Heard JM; Danos O
    J Virol; 1995 Jan; 69(1):528-33. PubMed ID: 7983750
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Two sorting motifs, a ubiquitination motif and a tyrosine motif, are involved in HIV-1 and simian immunodeficiency virus Nef-mediated receptor endocytosis.
    Cai CY; Zhang X; Sinko PJ; Burakoff SJ; Jin YJ
    J Immunol; 2011 May; 186(10):5807-14. PubMed ID: 21482738
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain.
    Aiken C; Konner J; Landau NR; Lenburg ME; Trono D
    Cell; 1994 Mar; 76(5):853-64. PubMed ID: 8124721
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Nef- and phorbol ester-induced CD4 degradation by macrolide antibiotics.
    Luo T; Anderson SJ; Garcia JV
    J Virol; 1996 Mar; 70(3):1527-34. PubMed ID: 8627671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase.
    Laguette N; Brégnard C; Bouchet J; Benmerah A; Benichou S; Basmaciogullari S
    J Virol; 2009 Jul; 83(14):7117-28. PubMed ID: 19439470
    [TBL] [Abstract][Full Text] [Related]  

  • 17. How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
    Ren X; Park SY; Bonifacino JS; Hurley JH
    Elife; 2014; 3():e01754. PubMed ID: 24473078
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cell-based Fluorescence Complementation Reveals a Role for HIV-1 Nef Protein Dimerization in AP-2 Adaptor Recruitment and CD4 Co-receptor Down-regulation.
    Shu ST; Emert-Sedlak LA; Smithgall TE
    J Biol Chem; 2017 Feb; 292(7):2670-2678. PubMed ID: 28031466
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent.
    Jin YJ; Cai CY; Zhang X; Zhang HT; Hirst JA; Burakoff SJ
    J Immunol; 2005 Sep; 175(5):3157-64. PubMed ID: 16116206
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The di-leucine motif in the cytoplasmic tail of CD4 is not required for binding to human immunodeficiency virus type 1 Nef, but is critical for CD4 down-modulation.
    Bentham M; Mazaleyrat S; Harris M
    J Gen Virol; 2003 Oct; 84(Pt 10):2705-2713. PubMed ID: 13679604
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.