276 related articles for article (PubMed ID: 19404540)
1. A long-lasting, plasmin-activatable thrombin inhibitor aids clot lysis in vitro and does not promote bleeding in vivo.
Sheffield WP; Eltringham-Smith LJ; Gataiance S; Bhakta V
Thromb Haemost; 2009 May; 101(5):867-77. PubMed ID: 19404540
[TBL] [Abstract][Full Text] [Related]
2. A factor XIa-activatable hirudin-albumin fusion protein reduces thrombosis in mice without promoting blood loss.
Sheffield WP; Eltringham-Smith LJ; Bhakta V
BMC Biotechnol; 2018 Apr; 18(1):21. PubMed ID: 29621998
[TBL] [Abstract][Full Text] [Related]
3. A plasmin-activatable thrombin inhibitor reduces experimental thrombosis and assists experimental thrombolysis in murine models.
Sheffield WP; Eltringham-Smith LJ; Gataiance S; Bhakta V
J Thromb Thrombolysis; 2015 May; 39(4):443-51. PubMed ID: 25481811
[TBL] [Abstract][Full Text] [Related]
4. A fusion protein with improved thrombolytic effect and low bleeding risk.
Wang X; Zhang G; Wang L; Zhang Q; Qin Y; Wu C; Yu A
Thromb Haemost; 2009 Dec; 102(6):1194-203. PubMed ID: 19967151
[TBL] [Abstract][Full Text] [Related]
5. Prolonged in vivo anticoagulant activity of a hirudin-albumin fusion protein secreted from Pichia pastoris.
Sheffield WP; Smith IJ; Syed S; Bhakta V
Blood Coagul Fibrinolysis; 2001 Sep; 12(6):433-43. PubMed ID: 11555696
[TBL] [Abstract][Full Text] [Related]
6. Modular design of a novel chimeric protein with combined thrombin inhibitory activity and plasminogen-activating potential.
Wirsching F; Luge C; Schwienhorst A
Mol Genet Metab; 2002 Mar; 75(3):250-9. PubMed ID: 11914037
[TBL] [Abstract][Full Text] [Related]
7. Antithrombotic and haemorrhagic effects of the naturally occurring thrombin inhibitor hirudin.
Kaiser B; Markwardt F
Folia Haematol Int Mag Klin Morphol Blutforsch; 1988; 115(1-2):41-6. PubMed ID: 2459030
[TBL] [Abstract][Full Text] [Related]
8. Construction and functional evaluation of hirudin derivatives with low bleeding risk.
Zhang C; Yu A; Yuan B; Dong C; Yu H; Wang L; Wu C
Thromb Haemost; 2008 Feb; 99(2):324-30. PubMed ID: 18278181
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of thrombin by hirudin genetically fused to wild-type or mutant antithrombin.
Syed S; Kelly KE; Sheffield WP
Thromb Res; 1996 Dec; 84(6):419-29. PubMed ID: 8987163
[TBL] [Abstract][Full Text] [Related]
10. Potent antithrombin activity and delayed clearance from the circulation characterize recombinant hirudin genetically fused to albumin.
Syed S; Schuyler PD; Kulczycky M; Sheffield WP
Blood; 1997 May; 89(9):3243-52. PubMed ID: 9129029
[TBL] [Abstract][Full Text] [Related]
11. Combined administration of barbourin--albumin and hirudin--albumin fusion proteins limits fibrin(ogen) deposition on the rabbit balloon-injured aorta.
Sheffield WP; Gataiance S; Eltringham-Smith LJ
Thromb Res; 2007; 119(2):195-207. PubMed ID: 16478628
[TBL] [Abstract][Full Text] [Related]
12. Preparation and characterization of a novel exendin-4 human serum albumin fusion protein expressed in Pichia pastoris.
Huang YS; Chen Z; Chen YQ; Ma GC; Shan JF; Liu W; Zhou LF
J Pept Sci; 2008 May; 14(5):588-95. PubMed ID: 17994612
[TBL] [Abstract][Full Text] [Related]
13. [Construction and expression of a fusion protein made of tissue-type plasminogen activator and hirudin in Pichia pastoris].
Yu AP; Shi BX; Dong CN; Jiang ZH; Wu ZZ
Sheng Wu Gong Cheng Xue Bao; 2005 Jul; 21(4):553-7. PubMed ID: 16176091
[TBL] [Abstract][Full Text] [Related]
14. [Purification and activity assay of HSA-AX15 (R13K) fusion protein expressed in Pichia pastoris].
Zhao HL; Xue C; Xiong XH; Zhang W; Yang BF; Liu ZM
Sheng Wu Gong Cheng Xue Bao; 2005 Mar; 21(2):254-8. PubMed ID: 16013485
[TBL] [Abstract][Full Text] [Related]
15. Antithrombotic effects due to pharmacological modulation of thrombin-activatable fibrinolysis inhibitor in rats.
Soni H; Sharma A; Bhatt S; Jain MR; Patel PR
Pharmacology; 2008; 82(4):304-9. PubMed ID: 18936552
[TBL] [Abstract][Full Text] [Related]
16. A barbourin-albumin fusion protein that is slowly cleared in vivo retains the ability to inhibit platelet aggregation in vitro.
Marques JA; George JK; Smith IJ; Bhakta V; Sheffield WP
Thromb Haemost; 2001 Sep; 86(3):902-8. PubMed ID: 11583325
[TBL] [Abstract][Full Text] [Related]
17. A covalently linked recombinant albumin dimer is more rapidly cleared in vivo than are wild-type and mutant C34A albumin.
McCurdy TR; Gataiance S; Eltringham-Smith LJ; Sheffield WP
J Lab Clin Med; 2004 Feb; 143(2):115-24. PubMed ID: 14966467
[TBL] [Abstract][Full Text] [Related]
18. Plasmin induces local thrombolysis without causing hemorrhage: a comparison with tissue plasminogen activator in the rabbit.
Marder VJ; Landskroner K; Novokhatny V; Zimmerman TP; Kong M; Kanouse JJ; Jesmok G
Thromb Haemost; 2001 Sep; 86(3):739-45. PubMed ID: 11583303
[TBL] [Abstract][Full Text] [Related]
19. Expression, purification, and characterization of recombinant human serum albumin fusion protein with two human glucagon-like peptide-1 mutants in Pichia pastoris.
Dou WF; Lei JY; Zhang LF; Xu ZH; Chen Y; Jin J
Protein Expr Purif; 2008 Sep; 61(1):45-9. PubMed ID: 18556214
[TBL] [Abstract][Full Text] [Related]
20. Construction and characterization of a potent, long-lasting recombinant human serum albumin-interferon α1 fusion protein expressed in Pichia pastoris.
Tian S; Li Q; Yao W; Xu C
Protein Expr Purif; 2013 Aug; 90(2):124-8. PubMed ID: 23748141
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
