These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Screening BRCA1 and BRCA2 unclassified variants for splicing mutations using reverse transcription PCR on patient RNA and an ex vivo assay based on a splicing reporter minigene. Bonnet C; Krieger S; Vezain M; Rousselin A; Tournier I; Martins A; Berthet P; Chevrier A; Dugast C; Layet V; Rossi A; Lidereau R; Frébourg T; Hardouin A; Tosi M J Med Genet; 2008 Jul; 45(7):438-46. PubMed ID: 18424508 [TBL] [Abstract][Full Text] [Related]
4. The variants BRCA1 IVS6-1G>A and BRCA2 IVS15+1G>A lead to aberrant splicing of the transcripts. Gutiérrez-Enríquez S; Coderch V; Masas M; Balmaña J; Diez O Breast Cancer Res Treat; 2009 Sep; 117(2):461-5. PubMed ID: 18712473 [TBL] [Abstract][Full Text] [Related]
5. Prediction of single-nucleotide substitutions that result in exon skipping: identification of a splicing silencer in BRCA1 exon 6. Raponi M; Kralovicova J; Copson E; Divina P; Eccles D; Johnson P; Baralle D; Vorechovsky I Hum Mutat; 2011 Apr; 32(4):436-44. PubMed ID: 21309043 [TBL] [Abstract][Full Text] [Related]
6. RNA analysis of eight BRCA1 and BRCA2 unclassified variants identified in breast/ovarian cancer families from Spain. Campos B; Díez O; Domènech M; Baena M; Balmaña J; Sanz J; Ramírez A; Alonso C; Baiget M Hum Mutat; 2003 Oct; 22(4):337. PubMed ID: 12955719 [TBL] [Abstract][Full Text] [Related]
7. An exon skipping-associated nonsense mutation in the dystrophin gene uncovers a complex interplay between multiple antagonistic splicing elements. Disset A; Bourgeois CF; Benmalek N; Claustres M; Stevenin J; Tuffery-Giraud S Hum Mol Genet; 2006 Mar; 15(6):999-1013. PubMed ID: 16461336 [TBL] [Abstract][Full Text] [Related]
8. Detection of germline mutations in the BRCA1 gene by RNA-based sequencing. Jakubowska A; Górski B; Byrski T; Huzarski T; Gronwald J; Menkiszak J; Cybulski C; Debniak T; Hadaczek P; Scott RJ; Lubinski J Hum Mutat; 2001 Aug; 18(2):149-56. PubMed ID: 11462239 [TBL] [Abstract][Full Text] [Related]
9. Characterisation of unclassified variants in the BRCA1/2 genes with a putative effect on splicing. Brandão RD; van Roozendaal K; Tserpelis D; Gómez García E; Blok MJ Breast Cancer Res Treat; 2011 Oct; 129(3):971-82. PubMed ID: 21638052 [TBL] [Abstract][Full Text] [Related]
10. A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes. Liu HX; Cartegni L; Zhang MQ; Krainer AR Nat Genet; 2001 Jan; 27(1):55-8. PubMed ID: 11137998 [TBL] [Abstract][Full Text] [Related]
11. A specific GFP expression assay, penetrance estimate, and histological assessment for a putative splice site mutation in BRCA1. Southey MC; Tesoriero A; Young MA; Holloway AJ; Jenkins MA; Whitty J; Misfud S; kConFab ; McLachlan SA; Venter DJ; Armes JE Hum Mutat; 2003 Jul; 22(1):86-91. PubMed ID: 12815598 [TBL] [Abstract][Full Text] [Related]
12. Evolutionary conservation analysis increases the colocalization of predicted exonic splicing enhancers in the BRCA1 gene with missense sequence changes and in-frame deletions, but not polymorphisms. Pettigrew C; Wayte N; Lovelock PK; Tavtigian SV; Chenevix-Trench G; Spurdle AB; Brown MA Breast Cancer Res; 2005; 7(6):R929-39. PubMed ID: 16280041 [TBL] [Abstract][Full Text] [Related]
13. Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition. Mirkovic N; Marti-Renom MA; Weber BL; Sali A; Monteiro AN Cancer Res; 2004 Jun; 64(11):3790-7. PubMed ID: 15172985 [TBL] [Abstract][Full Text] [Related]
14. Differentiating pathogenic mutations from polymorphic alterations in the splice sites of BRCA1 and BRCA2. Claes K; Poppe B; Machackova E; Coene I; Foretova L; De Paepe A; Messiaen L Genes Chromosomes Cancer; 2003 Jul; 37(3):314-20. PubMed ID: 12759930 [TBL] [Abstract][Full Text] [Related]
15. Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice-site prediction programs. Vreeswijk MP; Kraan JN; van der Klift HM; Vink GR; Cornelisse CJ; Wijnen JT; Bakker E; van Asperen CJ; Devilee P Hum Mutat; 2009 Jan; 30(1):107-14. PubMed ID: 18693280 [TBL] [Abstract][Full Text] [Related]
16. The R71G BRCA1 is a founder Spanish mutation and leads to aberrant splicing of the transcript. Vega A; Campos B; Bressac-De-Paillerets B; Bond PM; Janin N; Douglas FS; Domènech M; Baena M; Pericay C; Alonso C; Carracedo A; Baiget M; Diez O Hum Mutat; 2001 Jun; 17(6):520-1. PubMed ID: 11385711 [TBL] [Abstract][Full Text] [Related]
17. The silent mutation nucleotide 744 G --> A, Lys172Lys, in exon 6 of BRCA2 results in exon skipping. Hansen TV; Steffensen AY; Jønson L; Andersen MK; Ejlertsen B; Nielsen FC Breast Cancer Res Treat; 2010 Feb; 119(3):547-50. PubMed ID: 19267246 [TBL] [Abstract][Full Text] [Related]
18. RNA-based analysis of BRCA1 and BRCA2 gene alterations. Bonatti F; Pepe C; Tancredi M; Lombardi G; Aretini P; Sensi E; Falaschi E; Cipollini G; Bevilacqua G; Caligo MA Cancer Genet Cytogenet; 2006 Oct; 170(2):93-101. PubMed ID: 17011978 [TBL] [Abstract][Full Text] [Related]
19. Unclassified variants identified in BRCA1 exon 11: Consequences on splicing. Anczuków O; Buisson M; Salles MJ; Triboulet S; Longy M; Lidereau R; Sinilnikova OM; Mazoyer S Genes Chromosomes Cancer; 2008 May; 47(5):418-26. PubMed ID: 18273839 [TBL] [Abstract][Full Text] [Related]
20. Modulation of exon skipping by high-affinity hnRNP A1-binding sites and by intron elements that repress splice site utilization. Blanchette M; Chabot B EMBO J; 1999 Apr; 18(7):1939-52. PubMed ID: 10202157 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]