160 related articles for article (PubMed ID: 19406953)
1. Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators.
Majumdar S; Hippalgaonkar K; Srirangam R
Drug Metab Dispos; 2009 Aug; 37(8):1718-25. PubMed ID: 19406953
[TBL] [Abstract][Full Text] [Related]
2. Interaction between topically and systemically coadministered P-glycoprotein substrates/inhibitors: effect on vitreal kinetics.
Hippalgaonkar K; Srirangam R; Avula B; Khan IA; Majumdar S
Drug Metab Dispos; 2010 Oct; 38(10):1790-7. PubMed ID: 20595378
[TBL] [Abstract][Full Text] [Related]
3. Effect of P-glycoprotein on the ocular disposition of a model substrate, quinidine.
Duvvuri S; Gandhi MD; Mitra AK
Curr Eye Res; 2003 Dec; 27(6):345-53. PubMed ID: 14704918
[TBL] [Abstract][Full Text] [Related]
4. Nonlinear pharmacokinetics of oral quinidine and verapamil in healthy subjects: a clinical microdosing study.
Maeda K; Takano J; Ikeda Y; Fujita T; Oyama Y; Nozawa K; Kumagai Y; Sugiyama Y
Clin Pharmacol Ther; 2011 Aug; 90(2):263-70. PubMed ID: 21716273
[TBL] [Abstract][Full Text] [Related]
5. Role of P-glycoprotein in distribution of rhodamine 123 into aqueous humor in rabbits.
Kajikawa T; Mishima HK; Murakami T; Takano M
Curr Eye Res; 1999 Mar; 18(3):240-6. PubMed ID: 10342379
[TBL] [Abstract][Full Text] [Related]
6. Effect of mdr1a P-glycoprotein gene disruption, gender, and substrate concentration on brain uptake of selected compounds.
Dagenais C; Zong J; Ducharme J; Pollack GM
Pharm Res; 2001 Jul; 18(7):957-63. PubMed ID: 11496955
[TBL] [Abstract][Full Text] [Related]
7. Pharmacokinetics of erythromycin in rabbit corneas after single-dose infusion: role of P-glycoprotein as a barrier to in vivo ocular drug absorption.
Dey S; Gunda S; Mitra AK
J Pharmacol Exp Ther; 2004 Oct; 311(1):246-55. PubMed ID: 15175422
[TBL] [Abstract][Full Text] [Related]
8. Distribution of verapamil and norverapamil in the eye and systemic circulation after topical administration of verapamil in rabbits.
Siegner SW; Giovanoni RL; Erickson KA; Netland PA
J Ocul Pharmacol Ther; 1998 Apr; 14(2):159-68. PubMed ID: 9572542
[TBL] [Abstract][Full Text] [Related]
9. Ocular pharmacokinetics in rabbits using a novel dual probe microdialysis technique.
Macha S; Mitra AK
Exp Eye Res; 2001 Mar; 72(3):289-99. PubMed ID: 11180978
[TBL] [Abstract][Full Text] [Related]
10. Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor.
Mendell J; Zahir H; Matsushima N; Noveck R; Lee F; Chen S; Zhang G; Shi M
Am J Cardiovasc Drugs; 2013 Oct; 13(5):331-42. PubMed ID: 23784266
[TBL] [Abstract][Full Text] [Related]
11. Ocular disposition of novel lipophilic diester prodrugs of ganciclovir following intravitreal administration using microdialysis.
Macha S; Duvvuri S; Mitra AK
Curr Eye Res; 2004 Feb; 28(2):77-84. PubMed ID: 14972713
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of the functional importance of organic cation transporters on the ocular disposition of its intravitreally injected substrate in rabbits.
Nirmal J; Velpandian T; Singh SB; Biswas NR; Azad R; Thavaraj V; Mittal G; Bhatnagar A; Ghose S
Curr Eye Res; 2012 Dec; 37(12):1127-35. PubMed ID: 22916711
[TBL] [Abstract][Full Text] [Related]
13. Circumventing P-glycoprotein-mediated cellular efflux of quinidine by prodrug derivatization.
Jain R; Majumdar S; Nashed Y; Pal D; Mitra AK
Mol Pharm; 2004; 1(4):290-9. PubMed ID: 15981588
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of the modulation of P-glycoprotein (P-gp) on the intraocular disposition of its substrate in rabbits.
Senthilkumari S; Velpandian T; Biswas NR; Saxena R; Ghose S
Curr Eye Res; 2008 Apr; 33(4):333-43. PubMed ID: 18398708
[TBL] [Abstract][Full Text] [Related]
15. Model analysis of the concentration-dependent permeability of P-gp substrates.
Tachibana T; Kitamura S; Kato M; Mitsui T; Shirasaka Y; Yamashita S; Sugiyama Y
Pharm Res; 2010 Mar; 27(3):442-6. PubMed ID: 20135207
[TBL] [Abstract][Full Text] [Related]
16. Effect of oral activated charcoal on the pharmacokinetics of quinidine and quinine administered intravenously to rabbits.
Hasan MM; Hassan MA; Rawashdeh NM
Pharmacol Toxicol; 1990 Jul; 67(1):73-6. PubMed ID: 2395819
[TBL] [Abstract][Full Text] [Related]
17. Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats.
Fujii S; Setoguchi C; Kawazu K; Hosoya K
Invest Ophthalmol Vis Sci; 2014 Jul; 55(7):4650-8. PubMed ID: 24985475
[TBL] [Abstract][Full Text] [Related]
18. Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.
Elsby R; Surry DD; Smith VN; Gray AJ
Xenobiotica; 2008 Jul; 38(7-8):1140-64. PubMed ID: 18668443
[TBL] [Abstract][Full Text] [Related]
19. Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition.
Yamazaki S; Evers R; De Zwart L
CPT Pharmacometrics Syst Pharmacol; 2022 Jan; 11(1):55-67. PubMed ID: 34668334
[TBL] [Abstract][Full Text] [Related]
20. Pharmacokinetic Modeling of (
García-Varela L; García DV; Kakiuchi T; Ohba H; Nishiyama S; Tago T; Elsinga PH; Tsukada H; Colabufo NA; Dierckx RAJO; van Waarde A; Toyohara J; Boellaard R; Luurtsema G
Mol Pharm; 2021 Jan; 18(1):416-428. PubMed ID: 33315404
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
