These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 19408950)

  • 1. SAR studies for a new class of antibacterial NAD biosynthesis inhibitors.
    Moro WB; Yang Z; Kane TA; Zhou Q; Harville S; Brouillette CG; Brouillette WJ
    J Comb Chem; 2009; 11(4):617-25. PubMed ID: 19408950
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Virtual screening to identify lead inhibitors for bacterial NAD synthetase (NADs).
    Moro WB; Yang Z; Kane TA; Brouillette CG; Brouillette WJ
    Bioorg Med Chem Lett; 2009 Apr; 19(7):2001-5. PubMed ID: 19249205
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis.
    Lu S; Smith CD; Yang Z; Pruett PS; Nagy L; McCombs D; Delucas LJ; Brouillette WJ; Brouillette CG
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Oct; 64(Pt 10):893-8. PubMed ID: 18931430
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD.
    Sorci L; Pan Y; Eyobo Y; Rodionova I; Huang N; Kurnasov O; Zhong S; MacKerell AD; Zhang H; Osterman AL
    Chem Biol; 2009 Aug; 16(8):849-61. PubMed ID: 19716475
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New antibiotics for anthrax?
    Sutherland S
    Drug Discov Today; 2003 Apr; 8(8):335-6. PubMed ID: 12681931
    [No Abstract]   [Full Text] [Related]  

  • 6. Comparative genomics of NAD(P) biosynthesis and novel antibiotic drug targets.
    Bi J; Wang H; Xie J
    J Cell Physiol; 2011 Feb; 226(2):331-40. PubMed ID: 20857400
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antibacterial nicotinamide adenine dinucleotide synthetase inhibitors: amide- and ether-linked tethered dimers with alpha-amino acid end groups.
    Velu SE; Mou L; Luan CH; Yang ZW; DeLucas LJ; Brouillette CG; Brouillette WJ
    J Med Chem; 2007 May; 50(11):2612-21. PubMed ID: 17489580
    [TBL] [Abstract][Full Text] [Related]  

  • 8. NAD(P) biosynthesis enzymes as potential targets for selective drug design.
    Magni G; Di Stefano M; Orsomando G; Raffaelli N; Ruggieri S
    Curr Med Chem; 2009; 16(11):1372-90. PubMed ID: 19355893
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tethered dimers as NAD synthetase inhibitors with antibacterial activity.
    Velu SE; Cristofoli WA; Garcia GJ; Brouillette CG; Pierson MC; Luan CH; DeLucas LJ; Brouillette WJ
    J Med Chem; 2003 Jul; 46(15):3371-81. PubMed ID: 12852767
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of inhibitors of thymidine monophosphate kinase from Bacillus anthracis.
    Byun Y; Vogel SR; Phipps AJ; Carnrot C; Eriksson S; Tiwari R; Tjarks W
    Nucleosides Nucleotides Nucleic Acids; 2008 Mar; 27(3):244-60. PubMed ID: 18260009
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD
    Wang X; Ahn YM; Lentscher AG; Lister JS; Brothers RC; Kneen MM; Gerratana B; Boshoff HI; Dowd CS
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4426-4430. PubMed ID: 28827112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity relationships of Bacillus cereus and Bacillus anthracis dihydrofolate reductase: toward the identification of new potent drug leads.
    Joska TM; Anderson AC
    Antimicrob Agents Chemother; 2006 Oct; 50(10):3435-43. PubMed ID: 17005826
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tethered dimer inhibitors of NAD synthetase: parallel synthesis of an aryl-substituted SAR library.
    Velu SE; Luan CH; Delucas LJ; Brouillette CG; Brouillette WJ
    J Comb Chem; 2005; 7(6):898-904. PubMed ID: 16283799
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement.
    Huang N; Kolhatkar R; Eyobo Y; Sorci L; Rodionova I; Osterman AL; Mackerell AD; Zhang H
    J Med Chem; 2010 Jul; 53(14):5229-39. PubMed ID: 20578699
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antibacterial evaluation of macrocyclic diarylheptanoid derivatives.
    Lin H; Bruhn DF; Maddox MM; Singh AP; Lee RE; Sun D
    Bioorg Med Chem Lett; 2016 Aug; 26(16):4070-6. PubMed ID: 27406794
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metabolic and bactericidal effects of targeted suppression of NadD and NadE enzymes in mycobacteria.
    Rodionova IA; Schuster BM; Guinn KM; Sorci L; Scott DA; Li X; Kheterpal I; Shoen C; Cynamon M; Locher C; Rubin EJ; Osterman AL
    mBio; 2014 Feb; 5(1):. PubMed ID: 24549842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genetic basis for sulfonamide resistance in Bacillus anthracis.
    Valderas MW; Bourne PC; Barrow WW
    Microb Drug Resist; 2007; 13(1):11-20. PubMed ID: 17536929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quinolinate salvage and insights for targeting NAD biosynthesis in group A streptococci.
    Sorci L; Blaby IK; Rodionova IA; De Ingeniis J; Tkachenko S; de Crécy-Lagard V; Osterman AL
    J Bacteriol; 2013 Feb; 195(4):726-32. PubMed ID: 23204464
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of nicotinic acid mononucleotide adenylyltransferase from Staphyloccocus aureus: structural basis for NaAD interaction in functional dimer.
    Han S; Forman MD; Loulakis P; Rosner MH; Xie Z; Wang H; Danley DE; Yuan W; Schafer J; Xu Z
    J Mol Biol; 2006 Jul; 360(4):814-25. PubMed ID: 16784754
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes.
    Qi J; Virga KG; Das S; Zhao Y; Yun MK; White SW; Lee RE
    Bioorg Med Chem; 2011 Feb; 19(3):1298-305. PubMed ID: 21216602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.