BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 19409520)

  • 1. Human RAD50 deficiency in a Nijmegen breakage syndrome-like disorder.
    Waltes R; Kalb R; Gatei M; Kijas AW; Stumm M; Sobeck A; Wieland B; Varon R; Lerenthal Y; Lavin MF; Schindler D; Dörk T
    Am J Hum Genet; 2009 May; 84(5):605-16. PubMed ID: 19409520
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cleavage of the BRCT tandem domains of nibrin by the 657del5 mutation affects the DNA damage response less than the Arg215Trp mutation.
    Mendez G; Cilli D; Berardinelli F; Viganotti M; Ascenzi P; Tanzarella C; Antoccia A; di Masi A
    IUBMB Life; 2012 Oct; 64(10):853-61. PubMed ID: 22941933
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bone Marrow Failure and Immunodeficiency Associated with Human RAD50 Variants.
    Takagi M; Hoshino A; Bousset K; Röddecke J; Martin HL; Folcut I; Tomomasa D; Yang X; Kobayashi J; Sakata N; Yoshida K; Miyano S; Ogawa S; Kojima S; Morio T; Dörk T; Kanegane H
    J Clin Immunol; 2023 Nov; 43(8):2136-2145. PubMed ID: 37794136
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two unrelated patients with MRE11A mutations and Nijmegen breakage syndrome-like severe microcephaly.
    Matsumoto Y; Miyamoto T; Sakamoto H; Izumi H; Nakazawa Y; Ogi T; Tahara H; Oku S; Hiramoto A; Shiiki T; Fujisawa Y; Ohashi H; Sakemi Y; Matsuura S
    DNA Repair (Amst); 2011 Mar; 10(3):314-21. PubMed ID: 21227757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.
    Shull ER; Lee Y; Nakane H; Stracker TH; Zhao J; Russell HR; Petrini JH; McKinnon PJ
    Genes Dev; 2009 Jan; 23(2):171-80. PubMed ID: 19171781
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human RAD50 deficiency: Confirmation of a distinctive phenotype.
    Ragamin A; Yigit G; Bousset K; Beleggia F; Verheijen FW; de Wit MY; Strom TM; Dörk T; Wollnik B; Mancini GMS
    Am J Med Genet A; 2020 Jun; 182(6):1378-1386. PubMed ID: 32212377
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
    Cerosaletti K; Concannon P
    J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATM protein-dependent phosphorylation of Rad50 protein regulates DNA repair and cell cycle control.
    Gatei M; Jakob B; Chen P; Kijas AW; Becherel OJ; Gueven N; Birrell G; Lee JH; Paull TT; Lerenthal Y; Fazry S; Taucher-Scholz G; Kalb R; Schindler D; Waltes R; Dörk T; Lavin MF
    J Biol Chem; 2011 Sep; 286(36):31542-56. PubMed ID: 21757780
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Importance of Germline and Somatic Alterations in Human
    Otahalova B; Volkova Z; Soukupova J; Kleiblova P; Janatova M; Vocka M; Macurek L; Kleibl Z
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982687
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
    Taylor AM; Groom A; Byrd PJ
    DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis of ataxia telangiectasia and related diseases.
    Ball LG; Xiao W
    Acta Pharmacol Sin; 2005 Aug; 26(8):897-907. PubMed ID: 16038621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
    Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
    J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A murine model of Nijmegen breakage syndrome.
    Williams BR; Mirzoeva OK; Morgan WF; Lin J; Dunnick W; Petrini JH
    Curr Biol; 2002 Apr; 12(8):648-53. PubMed ID: 11967151
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct functions of Nijmegen breakage syndrome in ataxia telangiectasia mutated-dependent responses to DNA damage.
    Lee JH; Xu B; Lee CH; Ahn JY; Song MS; Lee H; Canman CE; Lee JS; Kastan MB; Lim DS
    Mol Cancer Res; 2003 Jul; 1(9):674-81. PubMed ID: 12861053
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
    He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
    J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.
    Lee JH; Ghirlando R; Bhaskara V; Hoffmeyer MR; Gu J; Paull TT
    J Biol Chem; 2003 Nov; 278(46):45171-81. PubMed ID: 12966088
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair.
    Czornak K; Chughtai S; Chrzanowska KH
    J Appl Genet; 2008; 49(4):383-96. PubMed ID: 19029686
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.
    Hopfner KP
    Bioessays; 2014 Dec; 36(12):1170-8. PubMed ID: 25213441
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.