175 related articles for article (PubMed ID: 19411072)
1. Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis.
Grinkevich VV; Nikulenkov F; Shi Y; Enge M; Bao W; Maljukova A; Gluch A; Kel A; Sangfelt O; Selivanova G
Cancer Cell; 2009 May; 15(5):441-53. PubMed ID: 19411072
[TBL] [Abstract][Full Text] [Related]
2. RITA induces apoptosis in p53-null K562 leukemia cells by inhibiting STAT5, Akt, and NF-κB signaling pathways.
Mobaraki RN; Karimi M; Alikarami F; Farhadi E; Amini A; Bashash D; Paridar M; Kokhaei P; Rezvani MR; Kazemi A; Safa M
Anticancer Drugs; 2018 Oct; 29(9):847-853. PubMed ID: 30157040
[TBL] [Abstract][Full Text] [Related]
3. Dual targeting of wild-type and mutant p53 by small molecule RITA results in the inhibition of N-Myc and key survival oncogenes and kills neuroblastoma cells in vivo and in vitro.
Burmakin M; Shi Y; Hedström E; Kogner P; Selivanova G
Clin Cancer Res; 2013 Sep; 19(18):5092-103. PubMed ID: 23864164
[TBL] [Abstract][Full Text] [Related]
4. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.
Spinnler C; Hedström E; Li H; de Lange J; Nikulenkov F; Teunisse AF; Verlaan-de Vries M; Grinkevich V; Jochemsen AG; Selivanova G
Cell Death Differ; 2011 Nov; 18(11):1736-45. PubMed ID: 21546907
[TBL] [Abstract][Full Text] [Related]
5. Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling.
Watson JL; Greenshields A; Hill R; Hilchie A; Lee PW; Giacomantonio CA; Hoskin DW
Mol Carcinog; 2010 Jan; 49(1):13-24. PubMed ID: 19676105
[TBL] [Abstract][Full Text] [Related]
6. Loss of p53, rather than beta-catenin overexpression, induces survivin-mediated resistance to apoptosis in an esophageal cancer cell line.
Chang E; Donahue J; Smith A; Hornick J; Rao JN; Wang JY; Battafarano RJ
J Thorac Cardiovasc Surg; 2010 Jul; 140(1):225-32. PubMed ID: 20236666
[TBL] [Abstract][Full Text] [Related]
7. Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA.
Zhao CY; Grinkevich VV; Nikulenkov F; Bao W; Selivanova G
Cell Cycle; 2010 May; 9(9):1847-55. PubMed ID: 20436301
[TBL] [Abstract][Full Text] [Related]
8. The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer.
Roh JL; Ko JH; Moon SJ; Ryu CH; Choi JY; Koch WM
Cancer Lett; 2012 Dec; 325(1):35-41. PubMed ID: 22634494
[TBL] [Abstract][Full Text] [Related]
9. Chk2 mediates RITA-induced apoptosis.
de Lange J; Verlaan-de Vries M; Teunisse AF; Jochemsen AG
Cell Death Differ; 2012 Jun; 19(6):980-9. PubMed ID: 22158418
[TBL] [Abstract][Full Text] [Related]
10. A novel small molecule FL118 that selectively inhibits survivin, Mcl-1, XIAP and cIAP2 in a p53-independent manner, shows superior antitumor activity.
Ling X; Cao S; Cheng Q; Keefe JT; Rustum YM; Li F
PLoS One; 2012; 7(9):e45571. PubMed ID: 23029106
[TBL] [Abstract][Full Text] [Related]
11. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma.
Saha MN; Jiang H; Yang Y; Zhu X; Wang X; Schimmer AD; Qiu L; Chang H
PLoS One; 2012; 7(1):e30215. PubMed ID: 22276160
[TBL] [Abstract][Full Text] [Related]
12. Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53.
Ho TF; Ma CJ; Lu CH; Tsai YT; Wei YH; Chang JS; Lai JK; Cheuh PJ; Yeh CT; Tang PC; Tsai Chang J; Ko JL; Liu FS; Yen HE; Chang CC
Toxicol Appl Pharmacol; 2007 Dec; 225(3):318-28. PubMed ID: 17881028
[TBL] [Abstract][Full Text] [Related]
13. WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death.
Venkatesan B; Prabhu SD; Venkatachalam K; Mummidi S; Valente AJ; Clark RA; Delafontaine P; Chandrasekar B
Cell Signal; 2010 May; 22(5):809-20. PubMed ID: 20074638
[TBL] [Abstract][Full Text] [Related]
14. The p53 upregulated modulator of apoptosis (PUMA) chemosensitizes intrinsically resistant ovarian cancer cells to cisplatin by lowering the threshold set by Bcl-x(L) and Mcl-1.
Yuan Z; Cao K; Lin C; Li L; Liu HY; Zhao XY; Liu L; Deng HX; Li J; Nie CL; Wei YQ
Mol Med; 2011; 17(11-12):1262-74. PubMed ID: 21863213
[TBL] [Abstract][Full Text] [Related]
15. p53-dependent inhibition of TrxR1 contributes to the tumor-specific induction of apoptosis by RITA.
Hedström E; Eriksson S; Zawacka-Pankau J; Arnér ES; Selivanova G
Cell Cycle; 2009 Nov; 8(21):3584-91. PubMed ID: 19838062
[TBL] [Abstract][Full Text] [Related]
16. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
[TBL] [Abstract][Full Text] [Related]
17. Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer.
Chen M; Zhang H; Zhang G; Zhong A; Ma Q; Kai J; Tong Y; Xie S; Wang Y; Zheng H; Guo L; Lu R
Biochem Biophys Res Commun; 2018 Dec; 507(1-4):74-82. PubMed ID: 30454896
[TBL] [Abstract][Full Text] [Related]
18. Rescue of p53 function by small-molecule RITA in cervical carcinoma by blocking E6-mediated degradation.
Zhao CY; Szekely L; Bao W; Selivanova G
Cancer Res; 2010 Apr; 70(8):3372-81. PubMed ID: 20395210
[TBL] [Abstract][Full Text] [Related]
19. p53 represses c-Myc through induction of the tumor suppressor miR-145.
Sachdeva M; Zhu S; Wu F; Wu H; Walia V; Kumar S; Elble R; Watabe K; Mo YY
Proc Natl Acad Sci U S A; 2009 Mar; 106(9):3207-12. PubMed ID: 19202062
[TBL] [Abstract][Full Text] [Related]
20. p21/CDKN1A mediates negative regulation of transcription by p53.
Löhr K; Möritz C; Contente A; Dobbelstein M
J Biol Chem; 2003 Aug; 278(35):32507-16. PubMed ID: 12748190
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
