BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 19414262)

  • 41. Amino acid ester prodrugs of 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole enhance metabolic stability in vitro and in vivo.
    Lorenzi PL; Landowski CP; Song X; Borysko KZ; Breitenbach JM; Kim JS; Hilfinger JM; Townsend LB; Drach JC; Amidon GL
    J Pharmacol Exp Ther; 2005 Aug; 314(2):883-90. PubMed ID: 15901797
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Assessing the oral bioavailability of difluorosialic acid prodrugs, potent viral neuraminidase inhibitors, using a snapshot PK screening assay.
    Arns S; Tan J; Sun S; Galey A; Zisman N; Ross F; Udechukwu J; Dercho S; Gusti V; Paquette J; Webb M; Bourque E; Withers SG; Liggins R
    Bioorg Med Chem Lett; 2015 Jun; 25(12):2505-9. PubMed ID: 25980910
    [TBL] [Abstract][Full Text] [Related]  

  • 43. 2beta,3beta-Difluorosialic acid derivatives structurally modified at the C-4 position: synthesis and biological evaluation as inhibitors of human parainfluenza virus type 1.
    Ikeda K; Kitani S; Sato K; Suzuki T; Hosokawa C; Suzuki Y; Tanaka K; Sato M
    Carbohydr Res; 2004 May; 339(7):1367-72. PubMed ID: 15113676
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 1-(4-methanesulfonylphenyl)-5-aryl-1H-pyrazol-3-carboxylic acids: synthesis, nitric oxide release studies and anti-inflammatory activities.
    Abdellatif KR; Chowdhury MA; Dong Y; Knaus EE
    Bioorg Med Chem; 2008 Jul; 16(13):6528-34. PubMed ID: 18513975
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Synthesis and biological evaluation of ester prodrugs of Benzafibrate as orally active hypolipidemic agents.
    Bandgar BP; Sarangdhar RJ; Fruthous K; Mookkan J; Chaudhary S; Chavan HV; Bandgar SB; Kshirsagar VY
    Eur J Med Chem; 2012 Nov; 57():217-24. PubMed ID: 23059549
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Intracellular trapping of cycloSal-pronucleotides: modification of prodrugs with amino acid esters.
    Jessen HJ; Balzarini J; Meier C
    J Med Chem; 2008 Oct; 51(20):6592-8. PubMed ID: 18826203
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Pharmacokinetic mechanism involved in the prolonged high retention of laninamivir in mouse respiratory tissues after intranasal administration of its prodrug laninamivir octanoate.
    Koyama K; Nakai D; Takahashi M; Nakai N; Kobayashi N; Imai T; Izumi T
    Drug Metab Dispos; 2013 Jan; 41(1):180-7. PubMed ID: 23091189
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Synthesis and properties of ester-linked peptide nucleic acid prodrug conjugates.
    Bendifallah N; Kristensen E; Dahl O; Koppelhus U; Nielsen PE
    Bioconjug Chem; 2003; 14(3):588-92. PubMed ID: 12757383
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Synthesis and evaluation of a new phosphorylated ribavirin prodrug.
    Dong SD; Lin CC; Schroeder M
    Antiviral Res; 2013 Jul; 99(1):18-26. PubMed ID: 23624267
    [TBL] [Abstract][Full Text] [Related]  

  • 50. 2-Deoxy-2,3-didehydro-N-acetylneuraminic acid analogs structurally modified by thiocarbamoylalkyl groups at the C-4 position: Synthesis and biological evaluation as inhibitors of human parainfluenza virus type 1.
    Ikeda K; Sato K; Nishino R; Aoyama S; Suzuki T; Sato M
    Bioorg Med Chem; 2008 Jul; 16(14):6783-8. PubMed ID: 18555688
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Dual-Action Heteromultivalent Glycopolymers Stringently Block and Arrest Influenza A Virus Infection
    Parshad B; Schlecht MN; Baumgardt M; Ludwig K; Nie C; Rimondi A; Hönzke K; Angioletti-Uberti S; Khatri V; Schneider P; Herrmann A; Haag R; Hocke AC; Wolff T; Bhatia S
    Nano Lett; 2023 Jun; 23(11):4844-4853. PubMed ID: 37220024
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Synthesis of HCV replicase inhibitors: base-catalyzed synthesis of protected α-hydrazino esters and selective aerobic oxidation with catalytic Pt/Bi/C for synthesis of imidazole-4,5-dicarbaldehyde.
    Bowman RK; Brown AD; Cobb JH; Eaddy JF; Hatcher MA; Leivers MR; Miller JF; Mitchell MB; Patterson DE; Toczko MA; Xie S
    J Org Chem; 2013 Dec; 78(23):11680-90. PubMed ID: 24171666
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies.
    Abdel-Azeem AZ; Abdel-Hafez AA; El-Karamany GS; Farag HH
    Bioorg Med Chem; 2009 May; 17(10):3665-70. PubMed ID: 19398345
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Cyclopropanecarboxylic acid esters as potential prodrugs with enhanced hydrolytic stability.
    Bender DM; Peterson JA; McCarthy JR; Gunaydin H; Takano Y; Houk KN
    Org Lett; 2008 Feb; 10(3):509-11. PubMed ID: 18181639
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years.
    Sinokrot H; Smerat T; Najjar A; Karaman R
    Molecules; 2017 Oct; 22(10):. PubMed ID: 29035325
    [No Abstract]   [Full Text] [Related]  

  • 56. Synthesis and bioactivity of novel methyl 6-deoxy-6-(N'-alkyl/aryl-N''-benzothiazol-2-yl)guanidino-alpha-D-glucopyranosides.
    Liu YH; Cao LH
    Carbohydr Res; 2008 Mar; 343(4):615-25. PubMed ID: 18194802
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Systematic syntheses of influenza neuraminidase inhibitors: a series of carbosilane dendrimers uniformly functionalized with thioglycoside-type sialic acid moieties.
    Sakamoto J; Koyama T; Miyamoto D; Yingsakmongkon S; Hidari KI; Jampangern W; Suzuki T; Suzuki Y; Esumi Y; Nakamura T; Hatano K; Terunuma D; Matsuoka K
    Bioorg Med Chem; 2009 Aug; 17(15):5451-64. PubMed ID: 19592257
    [TBL] [Abstract][Full Text] [Related]  

  • 58. [Synthesis and antiviral activity of lupane triterpenoids with modified cycle E].
    Flekhter OB; Medvedeva NI; Kukovinets OS; Spirikhin LV; Galkin EG; Galin FZ; Golovanov DG; Pavlova NI; Savinova OV; Boreko EI; Tolstikov GA
    Bioorg Khim; 2007; 33(6):629-34. PubMed ID: 18173126
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation.
    Tortolani DR; Russell JW; Whiterock VJ; Hitchcock MJ; Ghazzouli I; Martin JC; Mansuri MM; Starrett JE
    J Pharm Sci; 1994 Mar; 83(3):339-43. PubMed ID: 8207678
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication.
    Tsukamoto Y; Hiono T; Yamada S; Matsuno K; Faist A; Claff T; Hou J; Namasivayam V; Vom Hemdt A; Sugimoto S; Ng JY; Christensen MH; Tesfamariam YM; Wolter S; Juranek S; Zillinger T; Bauer S; Hirokawa T; Schmidt FI; Kochs G; Shimojima M; Huang YS; Pichlmair A; Kümmerer BM; Sakoda Y; Schlee M; Brunotte L; Müller CE; Igarashi M; Kato H
    Science; 2023 Feb; 379(6632):586-591. PubMed ID: 36758070
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.