BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 19415349)

  • 1. Structural consequences of a 3'-->3' DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex.
    Qu Y; Tran MC; Farrell NP
    J Biol Inorg Chem; 2009 Aug; 14(6):969-77. PubMed ID: 19415349
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
    Hegmans A; Berners-Price SJ; Davies MS; Thomas DS; Humphreys AS; Farrell N
    J Am Chem Soc; 2004 Feb; 126(7):2166-80. PubMed ID: 14971952
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cooperative effects in long-range 1,4 DNA-DNA interstrand cross-links formed by polynuclear platinum complexes: an unexpected syn orientation of adenine bases outside the binding sites.
    Qu Y; Scarsdale NJ; Tran MC; Farrell NP
    J Biol Inorg Chem; 2003 Jan; 8(1-2):19-28. PubMed ID: 12459895
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes.
    Qu Y; Scarsdale NJ; Tran MC; Farrell N
    J Inorg Biochem; 2004 Oct; 98(10):1585-90. PubMed ID: 15458820
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
    Brabec V; Kaspárková J; Vrána O; Nováková O; Cox JW; Qu Y; Farrell N
    Biochemistry; 1999 May; 38(21):6781-90. PubMed ID: 10346899
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N
    Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: thermodynamic analysis and chemical probing.
    Malina J; Farrell NP; Brabec V
    Chem Asian J; 2011 Jun; 6(6):1566-74. PubMed ID: 21557487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
    Malina J; Kasparkova J; Farrell NP; Brabec V
    Nucleic Acids Res; 2011 Jan; 39(2):720-8. PubMed ID: 20833634
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA cross-linking patterns induced by an antitumor-active trinuclear platinum complex and comparison with its dinuclear analogue.
    Zhu J; Zhao Y; Zhu Y; Wu Z; Lin M; He W; Wang Y; Chen G; Dong L; Zhang J; Lu Y; Guo Z
    Chemistry; 2009; 15(21):5245-53. PubMed ID: 19350599
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.
    Ruhayel RA; Moniodis JJ; Yang X; Kasparkova J; Brabec V; Berners-Price SJ; Farrell NP
    Chemistry; 2009 Sep; 15(37):9365-74. PubMed ID: 19691069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unique structural properties of DNA interstrand cross-links formed by a new antitumor dinuclear Pt(ii) complex.
    Hrabina O; Kasparkova J; Suchankova T; Novohradsky V; Guo Z; Brabec V
    Metallomics; 2017 May; 9(5):494-500. PubMed ID: 28436510
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fast interstrand cross-linking of cisplatin-DNA monoadducts compared with intrastrand chelation: a kinetic study using hairpin-stabilized duplex oligonucleotides.
    Monjardet-Bas V; Chottard JC; Kozelka J
    Chemistry; 2002 Mar; 8(5):1144-50. PubMed ID: 11891902
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of geometric isomerism and anions on the kinetics and mechanism of the stepwise formation of long-range DNA interstrand cross-links by dinuclear platinum antitumor complexes.
    Zhang J; Thomas DS; Berners-Price SJ; Farrell N
    Chemistry; 2008; 14(21):6391-405. PubMed ID: 18537208
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
    Muchova T; Quintal SM; Farrell NP; Brabec V; Kasparkova J
    J Biol Inorg Chem; 2012 Feb; 17(2):239-45. PubMed ID: 21938443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair.
    Kasparkova J; Zehnulova J; Farrell N; Brabec V
    J Biol Chem; 2002 Dec; 277(50):48076-86. PubMed ID: 12226099
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers.
    Cox JW; Berners-Price SJ; Davies MS; Qu Y; Farrell N
    J Am Chem Soc; 2001 Feb; 123(7):1316-26. PubMed ID: 11456703
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies.
    Kaspárková J; Mellish KJ; Qu Y; Brabec V; Farrell N
    Biochemistry; 1996 Dec; 35(51):16705-13. PubMed ID: 8988007
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464.
    Zehnulova J; Kasparkova J; Farrell N; Brabec V
    J Biol Chem; 2001 Jun; 276(25):22191-9. PubMed ID: 11303029
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.
    Baruah H; Wright MW; Bierbach U
    Biochemistry; 2005 Apr; 44(16):6059-70. PubMed ID: 15835895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thermodynamic stability and energetics of DNA duplexes containing major intrastrand cross-links of second-generation antitumor dinuclear Pt(II) complexes.
    Florian J; Kasparkova J; Farrell NP; Brabec V
    J Biol Inorg Chem; 2012 Feb; 17(2):187-96. PubMed ID: 21894503
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.