BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

292 related articles for article (PubMed ID: 19416980)

  • 1. Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage response.
    Zhang YW; Jones TL; Martin SE; Caplen NJ; Pommier Y
    J Biol Chem; 2009 Jul; 284(27):18085-95. PubMed ID: 19416980
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison.
    Sakasai R; Teraoka H; Takagi M; Tibbetts RS
    J Biol Chem; 2010 May; 285(20):15201-15208. PubMed ID: 20304914
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A functional approach reveals a genetic and physical interaction between ribonucleotide reductase and CHK1 in mammalian cells.
    Taricani L; Shanahan F; Malinao MC; Beaumont M; Parry D
    PLoS One; 2014; 9(11):e111714. PubMed ID: 25375241
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG.
    Gong C; Liu H; Song R; Zhong T; Lou M; Wang T; Qi H; Shen J; Zhu L; Shao J
    Biochim Biophys Acta; 2016 Apr; 1859(4):612-26. PubMed ID: 26921499
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.
    Rieunier G; Wu X; Harris LE; Mills JV; Nandakumar A; Colling L; Seraia E; Hatch SB; Ebner DV; Folkes LK; Weyer-Czernilofsky U; Bogenrieder T; Ryan AJ; Macaulay VM
    Cancer Res; 2021 Apr; 81(8):2128-2141. PubMed ID: 33509941
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ku affects the ataxia and Rad 3-related/CHK1-dependent S phase checkpoint response after camptothecin treatment.
    Wang H; Wang X; Zhou XY; Chen DJ; Li GC; Iliakis G; Wang Y
    Cancer Res; 2002 May; 62(9):2483-7. PubMed ID: 11980637
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of the ATR-CHK1 Pathway in Ewing Sarcoma Cells Causes DNA Damage and Apoptosis via the CDK2-Mediated Degradation of RRM2.
    Koppenhafer SL; Goss KL; Terry WW; Gordon DJ
    Mol Cancer Res; 2020 Jan; 18(1):91-104. PubMed ID: 31649026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR; Aau MY; Zhuang L; Yu Q
    J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Progesterone and DNA damage encourage uterine cell proliferation and decidualization through up-regulating ribonucleotide reductase 2 expression during early pregnancy in mice.
    Lei W; Feng XH; Deng WB; Ni H; Zhang ZR; Jia B; Yang XL; Wang TS; Liu JL; Su RW; Liang XH; Qi QR; Yang ZM
    J Biol Chem; 2012 May; 287(19):15174-92. PubMed ID: 22403396
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells.
    Rodríguez-Bravo V; Guaita-Esteruelas S; Florensa R; Bachs O; Agell N
    Cancer Res; 2006 Sep; 66(17):8672-9. PubMed ID: 16951182
    [TBL] [Abstract][Full Text] [Related]  

  • 11. WRN helicase regulates the ATR-CHK1-induced S-phase checkpoint pathway in response to topoisomerase-I-DNA covalent complexes.
    Patro BS; Frøhlich R; Bohr VA; Stevnsner T
    J Cell Sci; 2011 Dec; 124(Pt 23):3967-79. PubMed ID: 22159421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cdk inhibition in human cells compromises chk1 function and activates a DNA damage response.
    Maude SL; Enders GH
    Cancer Res; 2005 Feb; 65(3):780-6. PubMed ID: 15705874
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HPV31 utilizes the ATR-Chk1 pathway to maintain elevated RRM2 levels and a replication-competent environment in differentiating Keratinocytes.
    Anacker DC; Aloor HL; Shepard CN; Lenzi GM; Johnson BA; Kim B; Moody CA
    Virology; 2016 Dec; 499():383-396. PubMed ID: 27764728
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus.
    E X; Pickering MT; Debatis M; Castillo J; Lagadinos A; Wang S; Lu S; Kowalik TF
    PLoS Pathog; 2011 May; 7(5):e1001342. PubMed ID: 21589897
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
    Syljuåsen RG; Sørensen CS; Hansen LT; Fugger K; Lundin C; Johansson F; Helleday T; Sehested M; Lukas J; Bartek J
    Mol Cell Biol; 2005 May; 25(9):3553-62. PubMed ID: 15831461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
    Ha K; Fiskus W; Rao R; Balusu R; Venkannagari S; Nalabothula NR; Bhalla KN
    Mol Cancer Ther; 2011 Jul; 10(7):1194-206. PubMed ID: 21566061
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential involvement of phosphatidylinositol 3-kinase-related protein kinases in hyperphosphorylation of replication protein A2 in response to replication-mediated DNA double-strand breaks.
    Sakasai R; Shinohe K; Ichijima Y; Okita N; Shibata A; Asahina K; Teraoka H
    Genes Cells; 2006 Mar; 11(3):237-46. PubMed ID: 16483312
    [TBL] [Abstract][Full Text] [Related]  

  • 18. E2F1 promote the aggressiveness of human colorectal cancer by activating the ribonucleotide reductase small subunit M2.
    Fang Z; Gong C; Liu H; Zhang X; Mei L; Song M; Qiu L; Luo S; Zhu Z; Zhang R; Gu H; Chen X
    Biochem Biophys Res Commun; 2015 Aug; 464(2):407-15. PubMed ID: 26093293
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis.
    Kurose A; Tanaka T; Huang X; Traganos F; Dai W; Darzynkiewicz Z
    Cytometry A; 2006 Apr; 69(4):212-21. PubMed ID: 16528719
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gli1 protein regulates the S-phase checkpoint in tumor cells via Bid protein, and its inhibition sensitizes to DNA topoisomerase 1 inhibitors.
    Tripathi K; Mani C; Barnett R; Nalluri S; Bachaboina L; Rocconi RP; Athar M; Owen LB; Palle K
    J Biol Chem; 2014 Nov; 289(45):31513-25. PubMed ID: 25253693
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.