These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

311 related articles for article (PubMed ID: 19417133)

  • 1. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.
    Datta J; Ghoshal K; Denny WA; Gamage SA; Brooke DG; Phiasivongsa P; Redkar S; Jacob ST
    Cancer Res; 2009 May; 69(10):4277-85. PubMed ID: 19417133
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal.
    Ghoshal K; Datta J; Majumder S; Bai S; Kutay H; Motiwala T; Jacob ST
    Mol Cell Biol; 2005 Jun; 25(11):4727-41. PubMed ID: 15899874
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells.
    Vispé S; Deroide A; Davoine E; Desjobert C; Lestienne F; Fournier L; Novosad N; Bréand S; Besse J; Busato F; Tost J; De Vries L; Cussac D; Riond J; Arimondo PB
    Oncotarget; 2015 Jun; 6(17):15265-82. PubMed ID: 25948775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of silenced tumor suppressor genes in prostate cancer cells by a novel energy restriction-mimetic agent.
    Lin HY; Kuo YC; Weng YI; Lai IL; Huang TH; Lin SP; Niu DM; Chen CS
    Prostate; 2012 Dec; 72(16):1767-78. PubMed ID: 22539223
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells.
    Cui X; Wakai T; Shirai Y; Yokoyama N; Hatakeyama K; Hirano S
    Hum Pathol; 2006 Mar; 37(3):298-311. PubMed ID: 16613325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA-intercalators causing rapid re-expression of methylated and silenced genes in cancer cells.
    Hossain MZ; Healey MA; Lee C; Poh W; Yerram SR; Patel K; Azad NS; Herman JG; Kern SE
    Oncotarget; 2013 Feb; 4(2):298-309. PubMed ID: 23593653
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators.
    Vaid M; Prasad R; Singh T; Jones V; Katiyar SK
    Toxicol Appl Pharmacol; 2012 Aug; 263(1):122-30. PubMed ID: 22749965
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.
    Liu WB; Cui ZH; Ao L; Zhou ZY; Zhou YH; Yuan XY; Xiang YL; Liu JY; Cao J
    Toxicol Appl Pharmacol; 2011 Feb; 251(1):70-8. PubMed ID: 21163286
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase.
    Benbrahim-Tallaa L; Waterland RA; Dill AL; Webber MM; Waalkes MP
    Environ Health Perspect; 2007 Oct; 115(10):1454-9. PubMed ID: 17938735
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.
    Kastl L; Brown I; Schofield AC
    Int J Oncol; 2010 May; 36(5):1235-41. PubMed ID: 20372798
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nanaomycin A selectively inhibits DNMT3B and reactivates silenced tumor suppressor genes in human cancer cells.
    Kuck D; Caulfield T; Lyko F; Medina-Franco JL
    Mol Cancer Ther; 2010 Nov; 9(11):3015-23. PubMed ID: 20833755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
    Schneider-Stock R; Diab-Assef M; Rohrbeck A; Foltzer-Jourdainne C; Boltze C; Hartig R; Schönfeld P; Roessner A; Gali-Muhtasib H
    J Pharmacol Exp Ther; 2005 Feb; 312(2):525-36. PubMed ID: 15547111
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation.
    Rilova E; Erdmann A; Gros C; Masson V; Aussagues Y; Poughon-Cassabois V; Rajavelu A; Jeltsch A; Menon Y; Novosad N; Gregoire JM; Vispé S; Schambel P; Ausseil F; Sautel F; Arimondo PB; Cantagrel F
    ChemMedChem; 2014 Mar; 9(3):590-601. PubMed ID: 24678024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA methyltransferase-1 inhibitors as epigenetic therapy for cancer.
    Singh V; Sharma P; Capalash N
    Curr Cancer Drug Targets; 2013 May; 13(4):379-99. PubMed ID: 23517596
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor.
    Gray SG; Baird AM; O'Kelly F; Nikolaidis G; Almgren M; Meunier A; Dockry E; Hollywood D; Ekström TJ; Perry AS; O'Byrne KJ
    Int J Mol Med; 2012 Dec; 30(6):1505-11. PubMed ID: 23007409
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Promoter methylation status of tumor suppressor genes and inhibition of expression of DNA methyltransferase 1 in non-small cell lung cancer.
    Liu B; Song J; Luan J; Sun X; Bai J; Wang H; Li A; Zhang L; Feng X; Du Z
    Exp Biol Med (Maywood); 2016 Aug; 241(14):1531-9. PubMed ID: 27190263
    [TBL] [Abstract][Full Text] [Related]  

  • 17. (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.
    Nandakumar V; Vaid M; Katiyar SK
    Carcinogenesis; 2011 Apr; 32(4):537-44. PubMed ID: 21209038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
    Robert MF; Morin S; Beaulieu N; Gauthier F; Chute IC; Barsalou A; MacLeod AR
    Nat Genet; 2003 Jan; 33(1):61-5. PubMed ID: 12496760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.
    Yan L; Nass SJ; Smith D; Nelson WG; Herman JG; Davidson NE
    Cancer Biol Ther; 2003; 2(5):552-6. PubMed ID: 14614325
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.
    Cheng JC; Weisenberger DJ; Gonzales FA; Liang G; Xu GL; Hu YG; Marquez VE; Jones PA
    Mol Cell Biol; 2004 Feb; 24(3):1270-8. PubMed ID: 14729971
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.