311 related articles for article (PubMed ID: 19419861)
1. Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide release studies.
Abdellatif KR; Chowdhury MA; Dong Y; Das D; Yu G; Velázquez CA; Suresh MR; Knaus EE
Bioorg Med Chem Lett; 2009 Jun; 19(11):3014-8. PubMed ID: 19419861
[TBL] [Abstract][Full Text] [Related]
2. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
Velázquez C; Praveen Rao PN; Knaus EE
J Med Chem; 2005 Jun; 48(12):4061-7. PubMed ID: 15943479
[TBL] [Abstract][Full Text] [Related]
3. Hantzsch 1,4-dihydropyridines containing a diazen-1-ium-1,2-diolate nitric oxide donor moiety to study calcium channel antagonist structure-activity relationships and nitric oxide release.
Nguyen JT; Velázquez CA; Knaus EE
Bioorg Med Chem; 2005 Mar; 13(5):1725-38. PubMed ID: 15698790
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of 1,4-dihydropyridine calcium channel modulators having a diazen-1-ium-1,2-diolate nitric oxide donor moiety for the potential treatment of congestive heart failure.
Velázquez C; Knaus EE
Bioorg Med Chem; 2004 Jul; 12(14):3831-40. PubMed ID: 15210150
[TBL] [Abstract][Full Text] [Related]
5. O2-acetoxymethyl-protected diazeniumdiolate-based NSAIDs (NONO-NSAIDs): synthesis, nitric oxide release, and biological evaluation studies.
Velázquez CA; Praveen Rao PN; Citro ML; Keefer LK; Knaus EE
Bioorg Med Chem; 2007 Jul; 15(14):4767-74. PubMed ID: 17509888
[TBL] [Abstract][Full Text] [Related]
6. Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin.
Cena C; Lolli ML; Lazzarato L; Guaita E; Morini G; Coruzzi G; McElroy SP; Megson IL; Fruttero R; Gasco A
J Med Chem; 2003 Feb; 46(5):747-54. PubMed ID: 12593655
[TBL] [Abstract][Full Text] [Related]
7. NO-donors (VII [1]): synthesis and cyclooxygenase inhibitory properties of N-and S-nitrooxypivaloyl-cysteine derivatives of naproxen -- a novel type of NO-NSAID.
Kartasasmita RE; Laufer S; Lehmann J
Arch Pharm (Weinheim); 2002 Aug; 335(8):363-6. PubMed ID: 12397619
[TBL] [Abstract][Full Text] [Related]
8. NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.
Zacharowski P; Breese E; Wood E; Del Soldato P; Warner T; Mitchell J
Eur J Pharmacol; 2005 Jan; 508(1-3):7-13. PubMed ID: 15680249
[TBL] [Abstract][Full Text] [Related]
9. Bifunctional constructs of aspirin and ibuprofen (non-steroidal anti-inflammatory drugs; NSAIDs) that express antibacterial and alkylation activities.
Bartzatt R; Cirillo SL; Cirillo JD; Donigan L
Biotechnol Appl Biochem; 2003 Jun; 37(Pt 3):273-82. PubMed ID: 12533193
[TBL] [Abstract][Full Text] [Related]
10. Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention.
Williams JL; Borgo S; Hasan I; Castillo E; Traganos F; Rigas B
Cancer Res; 2001 Apr; 61(8):3285-9. PubMed ID: 11309281
[TBL] [Abstract][Full Text] [Related]
11. Prodrugs. Part 3. 2-Formylphenyl esters of indomethacin, ketoprofen and ibuprofen and 6-substituted 2-formyl and 2-acylphenyl esters of aspirin.
Abordo EA; Bowden K; Huntington AP; Powell SL
Farmaco; 1998 Feb; 53(2):95-101. PubMed ID: 9604316
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents.
Velázquez C; Rao PN; McDonald R; Knaus EE
Bioorg Med Chem; 2005 Apr; 13(8):2749-57. PubMed ID: 15781386
[TBL] [Abstract][Full Text] [Related]
13. Nonsteroidal anti-inflammatory drugs inhibit expression of the inducible nitric oxide synthase gene.
Aeberhard EE; Henderson SA; Arabolos NS; Griscavage JM; Castro FE; Barrett CT; Ignarro LJ
Biochem Biophys Res Commun; 1995 Mar; 208(3):1053-9. PubMed ID: 7535524
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and anti-inflammatory evaluation of a series of novel amino acid-binding 1,5-diarylpyrazole derivatives.
Li MH; Yin LL; Cai MJ; Zhang WY; Huang Y; Wang X; Zhu XZ; Shen JK
Acta Pharmacol Sin; 2005 Jul; 26(7):865-72. PubMed ID: 15960895
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, pharmacological activity and hydrolytic behavior of glyceride prodrugs of ibuprofen.
Khan MS; Akhter M
Eur J Med Chem; 2005 Apr; 40(4):371-6. PubMed ID: 15804536
[TBL] [Abstract][Full Text] [Related]
16. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
Gong P; Cederbaum AI; Nieto N
Mol Pharmacol; 2004 Jan; 65(1):130-8. PubMed ID: 14722244
[TBL] [Abstract][Full Text] [Related]
17. Gastric and thymic assay of acute oral treatment of rats with nitric oxide esters of ibuprofen or indomethacin.
Downing JE; Madden JC; Ingram MJ; Rostron C
Biochem Biophys Res Commun; 2005 Aug; 334(2):646-53. PubMed ID: 16018970
[TBL] [Abstract][Full Text] [Related]
18. Alkyl ester prodrugs for improved topical delivery of ibuprofen.
Bansal AK; Khar RK; Dubey R; Sharma AK
Indian J Exp Biol; 2001 Mar; 39(3):280-3. PubMed ID: 11495290
[TBL] [Abstract][Full Text] [Related]
19. In vitro effect of different non-steroidal anti-inflammatory drugs on human polymorphonuclear leukocyte activity measured by luminol-dependent chemiluminescence of the whole blood.
Abdullah AS; Jawad AM; Al-Hashimi AH
Saudi Med J; 2001 Apr; 22(4):360-5. PubMed ID: 11331497
[TBL] [Abstract][Full Text] [Related]
20. Nitric oxide-donating nonsteroidal anti-inflammatory drugs inhibit the growth of various cultured human cancer cells: evidence of a tissue type-independent effect.
Kashfi K; Rayyan Y; Qiao LL; Williams JL; Chen J; Del Soldato P; Traganos F; Rigas B; Ryann Y
J Pharmacol Exp Ther; 2002 Dec; 303(3):1273-82. PubMed ID: 12438552
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
