BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 19421137)

  • 1. TAK1 kinase determines TRAIL sensitivity by modulating reactive oxygen species and cIAP.
    Morioka S; Omori E; Kajino T; Kajino-Sakamoto R; Matsumoto K; Ninomiya-Tsuji J
    Oncogene; 2009 Jun; 28(23):2257-65. PubMed ID: 19421137
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade.
    Choo MK; Kawasaki N; Singhirunnusorn P; Koizumi K; Sato S; Akira S; Saiki I; Sakurai H
    Mol Cancer Ther; 2006 Dec; 5(12):2970-6. PubMed ID: 17172402
    [TBL] [Abstract][Full Text] [Related]  

  • 3. TAK1 is required for survival of mouse fibroblasts treated with TRAIL, and does so by NF-kappaB dependent induction of cFLIPL.
    Lluis JM; Nachbur U; Cook WD; Gentle IE; Moujalled D; Moulin M; Wong WW; Khan N; Chau D; Callus BA; Vince JE; Silke J; Vaux DL
    PLoS One; 2010 Jan; 5(1):e8620. PubMed ID: 20062539
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Melittin, a major component of bee venom, sensitizes human hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating CaMKII-TAK1-JNK/p38 and inhibiting IkappaBalpha kinase-NFkappaB.
    Wang C; Chen T; Zhang N; Yang M; Li B; Lü X; Cao X; Ling C
    J Biol Chem; 2009 Feb; 284(6):3804-13. PubMed ID: 19074436
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB.
    Dai Y; Liu M; Tang W; Li Y; Lian J; Lawrence TS; Xu L
    BMC Cancer; 2009 Nov; 9():392. PubMed ID: 19895686
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.
    Diessenbacher P; Hupe M; Sprick MR; Kerstan A; Geserick P; Haas TL; Wachter T; Neumann M; Walczak H; Silke J; Leverkus M
    J Invest Dermatol; 2008 May; 128(5):1134-47. PubMed ID: 17989734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production.
    Vanlangenakker N; Vanden Berghe T; Bogaert P; Laukens B; Zobel K; Deshayes K; Vucic D; Fulda S; Vandenabeele P; Bertrand MJ
    Cell Death Differ; 2011 Apr; 18(4):656-65. PubMed ID: 21052097
    [TBL] [Abstract][Full Text] [Related]  

  • 8. TRAIL activates JNK and NF-κB through RIP1-dependent and -independent pathways.
    Zhang L; Dittmer MR; Blackwell K; Workman LM; Hostager B; Habelhah H
    Cell Signal; 2015 Feb; 27(2):306-14. PubMed ID: 25446254
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TAK1 regulates SCF expression to modulate PKBα activity that protects keratinocytes from ROS-induced apoptosis.
    Lam CR; Tan MJ; Tan SH; Tang MB; Cheung PC; Tan NS
    Cell Death Differ; 2011 Jul; 18(7):1120-9. PubMed ID: 21233843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TAK1 is a central mediator of NOD2 signaling in epidermal cells.
    Kim JY; Omori E; Matsumoto K; Núñez G; Ninomiya-Tsuji J
    J Biol Chem; 2008 Jan; 283(1):137-144. PubMed ID: 17965022
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity.
    Omori E; Morioka S; Matsumoto K; Ninomiya-Tsuji J
    J Biol Chem; 2008 Sep; 283(38):26161-8. PubMed ID: 18606807
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ablation of TAK1 upregulates reactive oxygen species and selectively kills tumor cells.
    Omori E; Matsumoto K; Zhu S; Smart RC; Ninomiya-Tsuji J
    Cancer Res; 2010 Nov; 70(21):8417-25. PubMed ID: 20959492
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Upregulation of Death Receptor 5 and Production of Reactive Oxygen Species Mediate Sensitization of PC-3 Prostate Cancer Cells to TRAIL Induced Apoptosis by Vitisin A.
    Shin D; Kwon HY; Sohn EJ; Nam MS; Kim JH; Lee JC; Ryu SY; Park B; Kim SH
    Cell Physiol Biochem; 2015; 36(3):1151-62. PubMed ID: 26111475
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs.
    Ganten TM; Haas TL; Sykora J; Stahl H; Sprick MR; Fas SC; Krueger A; Weigand MA; Grosse-Wilde A; Stremmel W; Krammer PH; Walczak H
    Cell Death Differ; 2004 Jul; 11 Suppl 1():S86-96. PubMed ID: 15105837
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Wogonin enhances antitumor activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo through ROS-mediated downregulation of cFLIPL and IAP proteins.
    Yang L; Wang Q; Li D; Zhou Y; Zheng X; Sun H; Yan J; Zhang L; Lin Y; Wang X
    Apoptosis; 2013 May; 18(5):618-26. PubMed ID: 23371323
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential cleavage of Mst1 by caspase-7/-3 is responsible for TRAIL-induced activation of the MAPK superfamily.
    Song JJ; Lee YJ
    Cell Signal; 2008 May; 20(5):892-906. PubMed ID: 18276109
    [TBL] [Abstract][Full Text] [Related]  

  • 17. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes.
    Wachter T; Sprick M; Hausmann D; Kerstan A; McPherson K; Stassi G; Bröcker EB; Walczak H; Leverkus M
    J Biol Chem; 2004 Dec; 279(51):52824-34. PubMed ID: 15459191
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumor necrosis factor-related apoptosis-inducing ligand receptors signal NF-kappaB and JNK activation and apoptosis through distinct pathways.
    Hu WH; Johnson H; Shu HB
    J Biol Chem; 1999 Oct; 274(43):30603-10. PubMed ID: 10521444
    [TBL] [Abstract][Full Text] [Related]  

  • 19. J7, a methyl jasmonate derivative, enhances TRAIL-mediated apoptosis through up-regulation of reactive oxygen species generation in human hepatoma HepG2 cells.
    Park C; Jin CY; Hwang HJ; Kim GY; Jung JH; Kim WJ; Yoo YH; Choi YH
    Toxicol In Vitro; 2012 Feb; 26(1):86-93. PubMed ID: 22079975
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The dietary flavonol fisetin enhances the apoptosis-inducing potential of TRAIL in prostate cancer cells.
    Szliszka E; Helewski KJ; Mizgala E; Krol W
    Int J Oncol; 2011 Oct; 39(4):771-9. PubMed ID: 21743964
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.