BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 19421453)

  • 1. Quinone methide chemistry of prekinamycins: 13C-labeling, spectral global fitting and in vitro studies.
    Khdour O; Skibo EB
    Org Biomol Chem; 2009 May; 7(10):2140-54. PubMed ID: 19421453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemistry of pyrrolo[1,2-a]indole- and pyrido[1,2-a]indole-based quinone methides. Mechanistic explanations for differences in cytostatic/cytotoxic properties.
    Khdour O; Skibo EB
    J Org Chem; 2007 Nov; 72(23):8636-47. PubMed ID: 17927245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bioactivation of tamoxifen to metabolite E quinone methide: reaction with glutathione and DNA.
    Fan PW; Bolton JL
    Drug Metab Dispos; 2001 Jun; 29(6):891-6. PubMed ID: 11353759
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bioactivation of the selective estrogen receptor modulator acolbifene to quinone methides.
    Liu J; Liu H; van Breemen RB; Thatcher GR; Bolton JL
    Chem Res Toxicol; 2005 Feb; 18(2):174-82. PubMed ID: 15720121
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of mitochondrial respiration by a para-quinone methide.
    Thompson DC; Perera K
    Biochem Biophys Res Commun; 1995 Apr; 209(1):6-11. PubMed ID: 7726864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Flash photolytic generation of ortho-quinone methide in aqueous solution and study of its chemistry in that medium.
    Chiang Y; Kresge AJ; Zhu Y
    J Am Chem Soc; 2001 Aug; 123(33):8089-94. PubMed ID: 11506565
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Indolequinone antitumor agents: correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity.
    Beall HD; Winski S; Swann E; Hudnott AR; Cotterill AS; O'Sullivan N; Green SJ; Bien R; Siegel D; Ross D; Moody CJ
    J Med Chem; 1998 Nov; 41(24):4755-66. PubMed ID: 9822546
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of analogue structures of the p-quinone methide moiety of kendomycin.
    Green MP; Pichlmair S; Marques MM; Martin HJ; Diwald O; Berger T; Mulzer J
    Org Lett; 2004 Sep; 6(18):3131-4. PubMed ID: 15330605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of (+/-)-Alboatrin.
    Rodriguez R; Adlington RM; Moses JE; Cowley A; Baldwin JE
    Org Lett; 2004 Sep; 6(20):3617-9. PubMed ID: 15387562
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Studies on quinones. Part 42: Synthesis of furylquinone and hydroquinones with antiproliferative activity against human tumor cell lines.
    Benites J; Valderrama JA; Rivera F; Rojo L; Campos N; Pedro M; José Nascimento MS
    Bioorg Med Chem; 2008 Jan; 16(2):862-8. PubMed ID: 17964791
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of isomerization of 4-propyl-o-quinone to its tautomeric p-quinone methide.
    Bolton JL; Wu HM; Hu LQ
    Chem Res Toxicol; 1996; 9(1):109-113. PubMed ID: 8924578
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antitumor activity of quinonoid derivatives of cannabinoids.
    Kogan NM; Rabinowitz R; Levi P; Gibson D; Sandor P; Schlesinger M; Mechoulam R
    J Med Chem; 2004 Jul; 47(15):3800-6. PubMed ID: 15239658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.
    Fan PW; Zhang F; Bolton JL
    Chem Res Toxicol; 2000 Jan; 13(1):45-52. PubMed ID: 10649966
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stabilization and first direct spectroscopic evidence of the o-quinone methide derived from vitamin E.
    Rosenau T; Potthast A; Elder T; Kosma P
    Org Lett; 2002 Nov; 4(24):4285-8. PubMed ID: 12443079
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Isolation and frontier molecular orbital investigation of bioactive quinone-methide triterpenoids from the bark of Salacia petenensis.
    Setzer WN; Holland MT; Bozeman CA; Rozmus GF; Setzer MC; Moriarity DM; Reeb S; Vogler B; Bates RB; Haber WA
    Planta Med; 2001 Feb; 67(1):65-9. PubMed ID: 11270725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of the benzopyran derived natural products (+/-)-lucidene and (+/-)-alboatrin.
    Rodriguez R; Moses JE; Adlington RM; Baldwin JE
    Org Biomol Chem; 2005 Oct; 3(19):3488-95. PubMed ID: 16172685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Indolequinone antitumour agents: correlation between quinone structure and rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase.
    Newsome JJ; Swann E; Hassani M; Bray KC; Slawin AM; Beall HD; Moody CJ
    Org Biomol Chem; 2007 May; 5(10):1629-40. PubMed ID: 17571194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1).
    Fryatt T; Pettersson HI; Gardipee WT; Bray KC; Green SJ; Slawin AM; Beall HD; Moody CJ
    Bioorg Med Chem; 2004 Apr; 12(7):1667-87. PubMed ID: 15028260
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deciphering the activation sequence of ferrociphenol anticancer drug candidates.
    Messina P; Labbé E; Buriez O; Hillard EA; Vessières A; Hamels D; Top S; Jaouen G; Frapart YM; Mansuy D; Amatore C
    Chemistry; 2012 May; 18(21):6581-7. PubMed ID: 22492462
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Studies on quinones. Part 45: novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines.
    Valderrama JA; Ibacache JA; Arancibia V; Rodriguez J; Theoduloz C
    Bioorg Med Chem; 2009 Apr; 17(7):2894-901. PubMed ID: 19269832
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.