350 related articles for article (PubMed ID: 19425198)
1. Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.
Hostetler KY
Antiviral Res; 2009 May; 82(2):A84-98. PubMed ID: 19425198
[TBL] [Abstract][Full Text] [Related]
2. The clinical potential of the acyclic (and cyclic) nucleoside phosphonates: the magic of the phosphonate bond.
De Clercq E
Biochem Pharmacol; 2011 Jul; 82(2):99-109. PubMed ID: 21501598
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro.
Valiaeva N; Beadle JR; Aldern KA; Trahan J; Hostetler KY
Antiviral Res; 2006 Oct; 72(1):10-9. PubMed ID: 16630664
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of herpesvirus replication by hexadecyloxypropyl esters of purine- and pyrimidine-based phosphonomethoxyethyl nucleoside phosphonates.
Prichard MN; Hartline CB; Harden EA; Daily SL; Beadle JR; Valiaeva N; Kern ER; Hostetler KY
Antimicrob Agents Chemother; 2008 Dec; 52(12):4326-30. PubMed ID: 18852272
[TBL] [Abstract][Full Text] [Related]
5. The Holý Trinity: the acyclic nucleoside phosphonates.
De Clercq E
Adv Pharmacol; 2013; 67():293-316. PubMed ID: 23886004
[TBL] [Abstract][Full Text] [Related]
6. Acyclic nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, herpes-, and poxvirus infections: the phosphonate bridge.
De Clercq E
Biochem Pharmacol; 2007 Apr; 73(7):911-22. PubMed ID: 17045247
[TBL] [Abstract][Full Text] [Related]
7. In vitro evaluation of the anti-orf virus activity of alkoxyalkyl esters of CDV, cCDV and (S)-HPMPA.
Dal Pozzo F; Andrei G; Lebeau I; Beadle JR; Hostetler KY; De Clercq E; Snoeck R
Antiviral Res; 2007 Jul; 75(1):52-7. PubMed ID: 17184854
[TBL] [Abstract][Full Text] [Related]
8. Alkoxyalkyl esters of 9-(s)-(3-hydroxy-2-phosphonomethoxypropyl) adenine are potent and selective inhibitors of hepatitis B virus (HBV) replication in vitro and in HBV transgenic mice in vivo.
Morrey JD; Korba BE; Beadle JR; Wyles DL; Hostetler KY
Antimicrob Agents Chemother; 2009 Jul; 53(7):2865-70. PubMed ID: 19398648
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses.
Beadle JR; Wan WB; Ciesla SL; Keith KA; Hartline C; Kern ER; Hostetler KY
J Med Chem; 2006 Mar; 49(6):2010-5. PubMed ID: 16539388
[TBL] [Abstract][Full Text] [Related]
10. Antiviral activities of novel 5-phosphono-pent-2-en-1-yl nucleosides and their alkoxyalkyl phosphonoesters.
Choo H; Beadle JR; Kern ER; Prichard MN; Keith KA; Hartline CB; Trahan J; Aldern KA; Korba BE; Hostetler KY
Antimicrob Agents Chemother; 2007 Feb; 51(2):611-5. PubMed ID: 17130297
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir.
Ruiz JC; Beadle JR; Aldern KA; Keith KA; Hartline CB; Kern ER; Hostetler KY
Antiviral Res; 2007 Jul; 75(1):87-90. PubMed ID: 17367874
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication.
Valiaeva N; Wyles DL; Schooley RT; Hwu JB; Beadle JR; Prichard MN; Hostetler KY
Bioorg Med Chem; 2011 Aug; 19(15):4616-25. PubMed ID: 21719300
[TBL] [Abstract][Full Text] [Related]
13. Evaluation of nucleoside phosphonates and their analogs and prodrugs for inhibition of orthopoxvirus replication.
Keith KA; Hitchcock MJ; Lee WA; Holý A; Kern ER
Antimicrob Agents Chemother; 2003 Jul; 47(7):2193-8. PubMed ID: 12821467
[TBL] [Abstract][Full Text] [Related]
14. New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity.
Krečmerová M; Dračínský M; Snoeck R; Balzarini J; Pomeisl K; Andrei G
Bioorg Med Chem; 2017 Sep; 25(17):4637-4648. PubMed ID: 28757102
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of hexadecyloxypropyl-9-R-[2-(Phosphonomethoxy)propyl]- adenine, CMX157, as a potential treatment for human immunodeficiency virus type 1 and hepatitis B virus infections.
Painter GR; Almond MR; Trost LC; Lampert BM; Neyts J; De Clercq E; Korba BE; Aldern KA; Beadle JR; Hostetler KY
Antimicrob Agents Chemother; 2007 Oct; 51(10):3505-9. PubMed ID: 17646420
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine.
Ruiz JC; Aldern KA; Beadle JR; Hartline CB; Kern ER; Hostetler KY
Antivir Chem Chemother; 2006; 17(2):89-95. PubMed ID: 17042330
[TBL] [Abstract][Full Text] [Related]
17. Xanthine-based acyclic nucleoside phosphonates with potent antiviral activity against varicella-zoster virus and human cytomegalovirus.
Baszczyňski O; Kaiser MM; Česnek M; Břehová P; Jansa P; Procházková E; Dračínský M; Snoeck R; Andrei G; Janeba Z
Antivir Chem Chemother; 2018; 26():2040206618813050. PubMed ID: 30497281
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine.
Ruiz J; Beadle JR; Buller RM; Schreiwer J; Prichard MN; Keith KA; Lewis KC; Hostetler KY
Bioorg Med Chem; 2011 May; 19(9):2950-8. PubMed ID: 21493074
[TBL] [Abstract][Full Text] [Related]
19. Antischistosomal activity of hexadecyloxypropyl cyclic 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine and other alkoxyalkyl esters of acyclic nucleoside phosphonates assessed by schistosome worm killing in vitro.
Botros SS; William S; Beadle JR; Valiaeva N; Hostetler KY
Antimicrob Agents Chemother; 2009 Dec; 53(12):5284-7. PubMed ID: 19704122
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety.
Tichý T; Andrei G; Snoeck R; Balzarini J; Dračínský M; Krečmerová M
Eur J Med Chem; 2012 Sep; 55():307-14. PubMed ID: 22858222
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
