BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 19428175)

  • 1. Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53.
    Rong JJ; Hu R; Qi Q; Gu HY; Zhao Q; Wang J; Mu R; You QD; Guo QL
    Cancer Lett; 2009 Oct; 284(1):102-12. PubMed ID: 19428175
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway.
    Rong JJ; Hu R; Song XM; Ha J; Lu N; Qi Q; Tao L; You QD; Guo QL
    Cancer Lett; 2010 Oct; 296(1):55-64. PubMed ID: 20413215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).
    Meng LH; Kohn KW; Pommier Y
    Oncogene; 2007 Jul; 26(33):4806-16. PubMed ID: 17297446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway.
    Choi HJ; Chung TW; Kang SK; Lee YC; Ko JH; Kim JG; Kim CH
    Glycobiology; 2006 Jul; 16(7):573-83. PubMed ID: 16574813
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of p21(Waf1/Cip1) by garcinol via downregulation of p38-MAPK signaling in p53-independent H1299 lung cancer.
    Yu SY; Liao CH; Chien MH; Tsai TY; Lin JK; Weng MS
    J Agric Food Chem; 2014 Mar; 62(9):2085-95. PubMed ID: 24533688
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression.
    Phillips DC; Hunt JT; Moneypenny CG; Maclean KH; McKenzie PP; Harris LC; Houghton JA
    Cell Death Differ; 2007 Oct; 14(10):1780-91. PubMed ID: 17627285
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.
    Zacharatos PV; Gorgoulis VG; Kotsinas A; Manolis EN; Liloglou T; Rassidakis AN; Kanavaros P; Field JD; Halazonetis T; Kittas C
    Anticancer Res; 1999; 19(1A):579-87. PubMed ID: 10226602
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells.
    Gu H; Wang X; Rao S; Wang J; Zhao J; Ren FL; Mu R; Yang Y; Qi Q; Liu W; Lu N; Ling H; You Q; Guo Q
    Mol Cancer Ther; 2008 Oct; 7(10):3298-305. PubMed ID: 18852133
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells.
    Bae I; Fan S; Bhatia K; Kohn KW; Fornace AJ; O'Connor PM
    Cancer Res; 1995 Jun; 55(11):2387-93. PubMed ID: 7757991
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway.
    Li M; Zhang Z; Hill DL; Wang H; Zhang R
    Cancer Res; 2007 Mar; 67(5):1988-96. PubMed ID: 17332326
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p21(Waf1/Cip1) expression and the p53/MDM2 feedback loop in gastric carcinogenesis.
    Craanen ME; Blok P; Offerhaus GJ; Meijer GA; Dekker W; Kuipers EJ; Meuwissen SG
    J Pathol; 1999 Dec; 189(4):481-6. PubMed ID: 10629547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation.
    Sørensen BH; Nielsen D; Thorsteinsdottir UA; Hoffmann EK; Lambert IH
    Am J Physiol Cell Physiol; 2016 Jun; 310(11):C857-73. PubMed ID: 26984736
    [TBL] [Abstract][Full Text] [Related]  

  • 13. WAF1/CIP1 increases the susceptibility of p53 non-functional malignant glioma cells to cisplatin-induced apoptosis.
    Kondo S; Barna BP; Kondo Y; Tanaka Y; Casey G; Liu J; Morimura T; Kaakaji R; Peterson JW; Werbel B; Barnett GH
    Oncogene; 1996 Sep; 13(6):1279-85. PubMed ID: 8808702
    [TBL] [Abstract][Full Text] [Related]  

  • 14. LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
    Liu W; Dai Q; Lu N; Wei L; Ha J; Rong J; Mu R; You Q; Li Z; Guo Q
    Biochem Cell Biol; 2011 Jun; 89(3):287-98. PubMed ID: 21491996
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genistein, a dietary isoflavone, down-regulates the MDM2 oncogene at both transcriptional and posttranslational levels.
    Li M; Zhang Z; Hill DL; Chen X; Wang H; Zhang R
    Cancer Res; 2005 Sep; 65(18):8200-8. PubMed ID: 16166295
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types.
    Moussa RS; Kovacevic Z; Richardson DR
    Oncotarget; 2015 Oct; 6(30):29694-711. PubMed ID: 26335183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
    Choi BH; Kim CG; Bae YS; Lim Y; Lee YH; Shin SY
    Cancer Res; 2008 Mar; 68(5):1369-77. PubMed ID: 18316600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential regulation of the p21/WAF-1 and mdm2 genes after high-dose UV irradiation: p53-dependent and p53-independent regulation of the mdm2 gene.
    Wu L; Levine AJ
    Mol Med; 1997 Jul; 3(7):441-51. PubMed ID: 9260156
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human papillomavirus 16/18 E6 oncoprotein is expressed in lung cancer and related with p53 inactivation.
    Cheng YW; Wu MF; Wang J; Yeh KT; Goan YG; Chiou HL; Chen CY; Lee H
    Cancer Res; 2007 Nov; 67(22):10686-93. PubMed ID: 18006810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways.
    Sheikh MS; Li XS; Chen JC; Shao ZM; Ordonez JV; Fontana JA
    Oncogene; 1994 Dec; 9(12):3407-15. PubMed ID: 7970699
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.