BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

405 related articles for article (PubMed ID: 19428339)

  • 1. S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts.
    Milek M; Karas Kuzelicki N; Smid A; Mlinaric-Rascan I
    Biochem Pharmacol; 2009 Jun; 77(12):1845-53. PubMed ID: 19428339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of thiopurine drugs on DNA methylation in relation to TPMT expression.
    Hogarth LA; Redfern CP; Teodoridis JM; Hall AG; Anderson H; Case MC; Coulthard SA
    Biochem Pharmacol; 2008 Oct; 76(8):1024-35. PubMed ID: 18708030
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential role of thiopurine methyltransferase in the cytotoxic effects of 6-mercaptopurine and 6-thioguanine on human leukemia cells.
    Karim H; Ghalali A; Lafolie P; Vitols S; Fotoohi AK
    Biochem Biophys Res Commun; 2013 Jul; 437(2):280-6. PubMed ID: 23811272
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.
    Dervieux T; Blanco JG; Krynetski EY; Vanin EF; Roussel MF; Relling MV
    Cancer Res; 2001 Aug; 61(15):5810-6. PubMed ID: 11479220
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of thiopurine S-methyltransferase polymorphism in the population of Serbia and Montenegro and mercaptopurine therapy tolerance in childhood acute lymphoblastic leukemia.
    Dokmanovic L; Urosevic J; Janic D; Jovanovic N; Petrucev B; Tosic N; Pavlovic S
    Ther Drug Monit; 2006 Dec; 28(6):800-6. PubMed ID: 17164697
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of three methods for measuring thiopurine methyltransferase activity in red blood cells and human leukemia cells.
    Karim H; Appell ML; Fotoohi A
    J Chromatogr B Analyt Technol Biomed Life Sci; 2013 Nov; 939():80-5. PubMed ID: 24113235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase.
    Krynetski EY; Krynetskaia NF; Yanishevski Y; Evans WE
    Mol Pharmacol; 1995 Jun; 47(6):1141-7. PubMed ID: 7603453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia?
    Fakhoury M; Andreu-Gallien J; Mahr A; Medard Y; Azougagh S; Vilmer E; Jacqz-Aigrain E
    J Clin Pharm Ther; 2007 Dec; 32(6):633-9. PubMed ID: 18021342
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Establishment of thiopurine S-methyltransferase gene knockdown in jurkat T-lymphocytes: an in vitro model of TPMT polymorphism.
    Misdaq M; Andag R; Oellerich M; Asif AR; von Ahsen N
    Ther Drug Monit; 2012 Oct; 34(5):584-92. PubMed ID: 22972540
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thiopurine S-methyltransferase phenotype-genotype correlation in children with acute lymphoblastic leukemia.
    Chrzanowska M; Kuehn M; Januszkiewicz-Lewandowska D; Kurzawski M; Droździk M
    Acta Pol Pharm; 2012; 69(3):405-10. PubMed ID: 22594254
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human lymphocyte thiopurine methyltransferase pharmacogenetics: effect of phenotype on 6-mercaptopurine-induced inhibition of mitogen stimulation.
    Van Loon JA; Weinshilboum RM
    J Pharmacol Exp Ther; 1987 Jul; 242(1):21-6. PubMed ID: 3612526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Individualization of thiopurine therapy: thiopurine S-methyltransferase and beyond.
    Karas-Kuzelicki N; Mlinaric-Rascan I
    Pharmacogenomics; 2009 Aug; 10(8):1309-22. PubMed ID: 19663675
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thiopurine methyltransferase polymorphisms and mercaptopurine tolerance in Turkish children with acute lymphoblastic leukemia.
    Albayrak M; Konyssova U; Kaya Z; Gursel T; Guntekin S; Percin EF; Kocak U
    Cancer Chemother Pharmacol; 2011 Nov; 68(5):1155-9. PubMed ID: 21400026
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The clinical impact of thiopurine methyltransferase polymorphisms on thiopurine treatment.
    Coulthard SA; Matheson EC; Hall AG; Hogarth LA
    Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1385-91. PubMed ID: 15571264
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Population pharmacokinetic and pharmacogenetic analysis of 6-mercaptopurine in paediatric patients with acute lymphoblastic leukaemia.
    Hawwa AF; Collier PS; Millership JS; McCarthy A; Dempsey S; Cairns C; McElnay JC
    Br J Clin Pharmacol; 2008 Dec; 66(6):826-37. PubMed ID: 18823306
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thiopurine drugs in the treatment of childhood leukaemia: the influence of inherited thiopurine methyltransferase activity on drug metabolism and cytotoxicity.
    Lennard L; Welch JC; Lilleyman JS
    Br J Clin Pharmacol; 1997 Nov; 44(5):455-61. PubMed ID: 9384462
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes.
    Milek M; Smid A; Tamm R; Kuzelicki NK; Metspalu A; Mlinaric-Rascan I
    Biochem Pharmacol; 2012 Apr; 83(7):969-76. PubMed ID: 22274639
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?
    Sanderson J; Ansari A; Marinaki T; Duley J
    Ann Clin Biochem; 2004 Jul; 41(Pt 4):294-302. PubMed ID: 15298741
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Significance of TPMT activity and TGNs level detection for individualizing 6-mercaptopurine chemotherapy].
    Gu LJ; Ye QD; Liang AB; Zhao JC; Xue HL; Tang YN; Chen J; Ye YC
    Zhonghua Xue Ye Xue Za Zhi; 2003 Jan; 24(1):18-21. PubMed ID: 12679004
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.
    Coulthard SA; Hogarth LA; Little M; Matheson EC; Redfern CP; Minto L; Hall AG
    Mol Pharmacol; 2002 Jul; 62(1):102-9. PubMed ID: 12065760
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.