BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

653 related articles for article (PubMed ID: 19432488)

  • 1. Structure-function analyses of isochorismate-pyruvate lyase from Pseudomonas aeruginosa suggest differing catalytic mechanisms for the two pericyclic reactions of this bifunctional enzyme.
    Luo Q; Olucha J; Lamb AL
    Biochemistry; 2009 Jun; 48(23):5239-45. PubMed ID: 19432488
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploration of swapping enzymatic function between two proteins: a simulation study of chorismate mutase and isochorismate pyruvate lyase.
    Choutko A; Eichenberger AP; van Gunsteren WF; Dolenc J
    Protein Sci; 2013 Jun; 22(6):809-22. PubMed ID: 23595942
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism and plasticity of isochorismate pyruvate lyase: a computational study.
    Martí S; Andrés J; Moliner V; Silla E; Tuñón I; Bertrán J
    J Am Chem Soc; 2009 Nov; 131(44):16156-61. PubMed ID: 19835359
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Entropic and enthalpic components of catalysis in the mutase and lyase activities of Pseudomonas aeruginosa PchB.
    Luo Q; Meneely KM; Lamb AL
    J Am Chem Soc; 2011 May; 133(18):7229-33. PubMed ID: 21504201
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis.
    Zwahlen J; Kolappan S; Zhou R; Kisker C; Tonge PJ
    Biochemistry; 2007 Jan; 46(4):954-64. PubMed ID: 17240979
    [TBL] [Abstract][Full Text] [Related]  

  • 6. pH Dependence of catalysis by Pseudomonas aeruginosa isochorismate-pyruvate lyase: implications for transition state stabilization and the role of lysine 42.
    Olucha J; Ouellette AN; Luo Q; Lamb AL
    Biochemistry; 2011 Aug; 50(33):7198-207. PubMed ID: 21751784
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Salicylate biosynthesis in Pseudomonas aeruginosa. Purification and characterization of PchB, a novel bifunctional enzyme displaying isochorismate pyruvate-lyase and chorismate mutase activities.
    Gaille C; Kast P; Haas D
    J Biol Chem; 2002 Jun; 277(24):21768-75. PubMed ID: 11937513
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modification of residue 42 of the active site loop with a lysine-mimetic side chain rescues isochorismate-pyruvate lyase activity in Pseudomonas aeruginosa PchB.
    Olucha J; Meneely KM; Lamb AL
    Biochemistry; 2012 Sep; 51(38):7525-32. PubMed ID: 22970849
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection.
    Künzler DE; Sasso S; Gamper M; Hilvert D; Kast P
    J Biol Chem; 2005 Sep; 280(38):32827-34. PubMed ID: 16036918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isochorismate pyruvate lyase: a pericyclic reaction mechanism?
    DeClue MS; Baldridge KK; Künzler DE; Kast P; Hilvert D
    J Am Chem Soc; 2005 Nov; 127(43):15002-3. PubMed ID: 16248620
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural genes for salicylate biosynthesis from chorismate in Pseudomonas aeruginosa.
    Serino L; Reimmann C; Baur H; Beyeler M; Visca P; Haas D
    Mol Gen Genet; 1995 Nov; 249(2):217-28. PubMed ID: 7500944
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure and mechanism of Pseudomonas aeruginosa PhzD, an isochorismatase from the phenazine biosynthetic pathway.
    Parsons JF; Calabrese K; Eisenstein E; Ladner JE
    Biochemistry; 2003 May; 42(19):5684-93. PubMed ID: 12741825
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The monofunctional chorismate mutase from Bacillus subtilis. Structure determination of chorismate mutase and its complexes with a transition state analog and prephenate, and implications for the mechanism of the enzymatic reaction.
    Chook YM; Gray JV; Ke H; Lipscomb WN
    J Mol Biol; 1994 Jul; 240(5):476-500. PubMed ID: 8046752
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Predicting an improvement of secondary catalytic activity of promiscuous isochorismate pyruvate lyase by computational design.
    Martí S; Andrés J; Moliner V; Silla E; Tuñón I; Bertran J
    J Am Chem Soc; 2008 Mar; 130(10):2894-5. PubMed ID: 18281989
    [No Abstract]   [Full Text] [Related]  

  • 15. Lysine221 is the general base residue of the isochorismate synthase from Pseudomonas aeruginosa (PchA) in a reaction that is diffusion limited.
    Meneely KM; Luo Q; Dhar P; Lamb AL
    Arch Biochem Biophys; 2013 Oct; 538(1):49-56. PubMed ID: 23942051
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of point mutation on enzymatic activity: correlation between protein electronic structure and motion in chorismate mutase reaction.
    Ishida T
    J Am Chem Soc; 2010 May; 132(20):7104-18. PubMed ID: 20426479
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of active site residues in Pseudomonas aeruginosa phosphomannomutase/phosphoglucomutase.
    Naught LE; Regni C; Beamer LJ; Tipton PA
    Biochemistry; 2003 Aug; 42(33):9946-51. PubMed ID: 12924943
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exhaustive mutagenesis of six secondary active-site residues in Escherichia coli chorismate mutase shows the importance of hydrophobic side chains and a helix N-capping position for stability and catalysis.
    Lassila JK; Keeffe JR; Kast P; Mayo SL
    Biochemistry; 2007 Jun; 46(23):6883-91. PubMed ID: 17506527
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Two crystal structures of the isochorismate pyruvate lyase from Pseudomonas aeruginosa.
    Zaitseva J; Lu J; Olechoski KL; Lamb AL
    J Biol Chem; 2006 Nov; 281(44):33441-9. PubMed ID: 16914555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.
    Pillai B; Cherney M; Diaper CM; Sutherland A; Blanchard JS; Vederas JC; James MN
    Biochem Biophys Res Commun; 2007 Nov; 363(3):547-53. PubMed ID: 17889830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.