291 related articles for article (PubMed ID: 19432880)
1. Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2.
Ohtsubo C; Shiokawa D; Kodama M; Gaiddon C; Nakagama H; Jochemsen AG; Taya Y; Okamoto K
Cancer Sci; 2009 Jul; 100(7):1291-9. PubMed ID: 19432880
[TBL] [Abstract][Full Text] [Related]
2. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
Okamoto K; Taya Y; Nakagama H
FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
[TBL] [Abstract][Full Text] [Related]
3. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
[TBL] [Abstract][Full Text] [Related]
4. A site-directed mutagenesis study of the MdmX RING domain.
Egorova O; Mis M; Sheng Y
Biochem Biophys Res Commun; 2014 May; 447(4):696-701. PubMed ID: 24755078
[TBL] [Abstract][Full Text] [Related]
5. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
Ghosh M; Huang K; Berberich SJ
Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
[TBL] [Abstract][Full Text] [Related]
6. Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX.
Hu B; Gilkes DM; Chen J
Cancer Res; 2007 Sep; 67(18):8810-7. PubMed ID: 17875722
[TBL] [Abstract][Full Text] [Related]
7. Efficient reactivation of p53 in cancer cells by a dual MdmX/Mdm2 inhibitor.
Qin L; Yang F; Zhou C; Chen Y; Zhang H; Su Z
J Am Chem Soc; 2014 Dec; 136(52):18023-33. PubMed ID: 25453499
[TBL] [Abstract][Full Text] [Related]
8. Peli1 Modulates the Subcellular Localization and Activity of Mdmx.
Li D; Tavana O; Sun SC; Gu W
Cancer Res; 2018 Jun; 78(11):2897-2910. PubMed ID: 29523541
[TBL] [Abstract][Full Text] [Related]
9. MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail.
Sanford JD; Yang J; Han J; Tollini LA; Jin A; Zhang Y
BMC Mol Cell Biol; 2021 Sep; 22(1):46. PubMed ID: 34551723
[TBL] [Abstract][Full Text] [Related]
10. Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans.
Linke K; Mace PD; Smith CA; Vaux DL; Silke J; Day CL
Cell Death Differ; 2008 May; 15(5):841-8. PubMed ID: 18219319
[TBL] [Abstract][Full Text] [Related]
11. Comparative study of the p53-mdm2 and p53-MDMX interfaces.
Böttger V; Böttger A; Garcia-Echeverria C; Ramos YF; van der Eb AJ; Jochemsen AG; Lane DP
Oncogene; 1999 Jan; 18(1):189-99. PubMed ID: 9926934
[TBL] [Abstract][Full Text] [Related]
12. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination.
Wang X; Wang J; Jiang X
J Biol Chem; 2011 Jul; 286(27):23725-34. PubMed ID: 21572037
[TBL] [Abstract][Full Text] [Related]
13. Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells.
Egorova O; Lau HH; McGraphery K; Sheng Y
Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32075226
[TBL] [Abstract][Full Text] [Related]
14. Mutual dependence of MDM2 and MDMX in their functional inactivation of p53.
Gu J; Kawai H; Nie L; Kitao H; Wiederschain D; Jochemsen AG; Parant J; Lozano G; Yuan ZM
J Biol Chem; 2002 May; 277(22):19251-4. PubMed ID: 11953423
[TBL] [Abstract][Full Text] [Related]
15. The MDM2 RING domain and central acidic domain play distinct roles in MDM2 protein homodimerization and MDM2-MDMX protein heterodimerization.
Leslie PL; Ke H; Zhang Y
J Biol Chem; 2015 May; 290(20):12941-50. PubMed ID: 25809483
[TBL] [Abstract][Full Text] [Related]
16. On the interaction mechanisms of a p53 peptide and nutlin with the MDM2 and MDMX proteins: a Brownian dynamics study.
ElSawy KM; Verma CS; Joseph TL; Lane DP; Twarock R; Caves LS
Cell Cycle; 2013 Feb; 12(3):394-404. PubMed ID: 23324352
[TBL] [Abstract][Full Text] [Related]
17. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
[TBL] [Abstract][Full Text] [Related]
18. Affinity-based screening of MDM2/MDMX-p53 interaction inhibitors by chemical array: identification of novel peptidic inhibitors.
Noguchi T; Oishi S; Honda K; Kondoh Y; Saito T; Kubo T; Kaneda M; Ohno H; Osada H; Fujii N
Bioorg Med Chem Lett; 2013 Jul; 23(13):3802-5. PubMed ID: 23726030
[TBL] [Abstract][Full Text] [Related]
19. MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond.
Marine JC; Jochemsen AG
Cold Spring Harb Perspect Med; 2016 Jul; 6(7):. PubMed ID: 27371671
[TBL] [Abstract][Full Text] [Related]
20. Phosphorylation of MdmX by CDK2/Cdc2(p34) is required for nuclear export of Mdm2.
Elias B; Laine A; Ronai Z
Oncogene; 2005 Apr; 24(15):2574-9. PubMed ID: 15735705
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
