These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 19433443)

  • 1. The ability of GAP1IP4BP to function as a Rap1 GTPase-activating protein (GAP) requires its Ras GAP-related domain and an arginine finger rather than an asparagine thumb.
    Kupzig S; Bouyoucef-Cherchalli D; Yarwood S; Sessions R; Cullen PJ
    Mol Cell Biol; 2009 Jul; 29(14):3929-40. PubMed ID: 19433443
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GAP1 family members constitute bifunctional Ras and Rap GTPase-activating proteins.
    Kupzig S; Deaconescu D; Bouyoucef D; Walker SA; Liu Q; Polte CL; Daumke O; Ishizaki T; Lockyer PJ; Wittinghofer A; Cullen PJ
    J Biol Chem; 2006 Apr; 281(15):9891-900. PubMed ID: 16431904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and functional analysis of the putative inositol 1,3,4, 5-tetrakisphosphate receptors GAP1(IP4BP) and GAP1(m).
    Bottomley JR; Reynolds JS; Lockyer PJ; Cullen PJ
    Biochem Biophys Res Commun; 1998 Sep; 250(1):143-9. PubMed ID: 9735347
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-function relationships of the mouse Gap1m. Determination of the inositol 1,3,4,5-tetrakisphosphate-binding domain.
    Fukuda M; Mikoshiba K
    J Biol Chem; 1996 Aug; 271(31):18838-42. PubMed ID: 8702543
    [TBL] [Abstract][Full Text] [Related]  

  • 5. GAP1IP4BP contains a novel group I pleckstrin homology domain that directs constitutive plasma membrane association.
    Cozier GE; Lockyer PJ; Reynolds JS; Kupzig S; Bottomley JR; Millard TH; Banting G; Cullen PJ
    J Biol Chem; 2000 Sep; 275(36):28261-8. PubMed ID: 10869341
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular modelling and site-directed mutagenesis of the inositol 1,3,4,5-tetrakisphosphate-binding pleckstrin homology domain from the Ras GTPase-activating protein GAP1IP4BP.
    Cozier G; Sessions R; Bottomley JR; Reynolds JS; Cullen PJ
    Biochem J; 2000 Jul; 349(Pt 1):333-42. PubMed ID: 10861245
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1IP4BP and GAP1m result from the GAP1IP4BP PH domain directing plasma membrane targeting.
    Lockyer PJ; Bottomley JR; Reynolds JS; McNulty TJ; Venkateswarlu K; Potter BV; Dempsey CE; Cullen PJ
    Curr Biol; 1997 Dec; 7(12):1007-10. PubMed ID: 9382842
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unravelling the mechanism of dual-specificity GAPs.
    Sot B; Kötting C; Deaconescu D; Suveyzdis Y; Gerwert K; Wittinghofer A
    EMBO J; 2010 Apr; 29(7):1205-14. PubMed ID: 20186121
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Domain topology of human Rasal.
    Cuellar J; Valpuesta JM; Wittinghofer A; Sot B
    Biol Chem; 2017 Dec; 399(1):63-72. PubMed ID: 28885980
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of Gln61 and Glu63 of Ras GTPases in their activation by NF1 and Ras GAP.
    Nur-E-Kamal MS; Maruta H
    Mol Biol Cell; 1992 Dec; 3(12):1437-42. PubMed ID: 1362901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions.
    Maekawa M; Li S; Iwamatsu A; Morishita T; Yokota K; Imai Y; Kohsaka S; Nakamura S; Hattori S
    Mol Cell Biol; 1994 Oct; 14(10):6879-85. PubMed ID: 7935405
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The GTPase-activating protein Rap1GAP uses a catalytic asparagine.
    Daumke O; Weyand M; Chakrabarti PP; Vetter IR; Wittinghofer A
    Nature; 2004 May; 429(6988):197-201. PubMed ID: 15141215
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Understanding the catalytic mechanism of GTPase-activating proteins: demonstration of the importance of switch domain stabilization in the stimulation of GTP hydrolysis.
    Fidyk NJ; Cerione RA
    Biochemistry; 2002 Dec; 41(52):15644-53. PubMed ID: 12501193
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct phosphoinositide binding specificity of the GAP1 family proteins: characterization of the pleckstrin homology domains of MRASAL and KIAA0538.
    Minagawa T; Fukuda M; Mikoshiba K
    Biochem Biophys Res Commun; 2001 Oct; 288(1):87-90. PubMed ID: 11594756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Ras/Rap GTPase activating protein RASA3: from gene structure to in vivo functions.
    Schurmans S; Polizzi S; Scoumanne A; Sayyed S; Molina-Ortiz P
    Adv Biol Regul; 2015 Jan; 57():153-61. PubMed ID: 25294679
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues.
    Scrima A; Thomas C; Deaconescu D; Wittinghofer A
    EMBO J; 2008 Apr; 27(7):1145-53. PubMed ID: 18309292
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural plasticity mediates distinct GAP-dependent GTP hydrolysis mechanisms in Rab33 and Rab5.
    Majumdar S; Acharya A; Prakash B
    FEBS J; 2017 Dec; 284(24):4358-4375. PubMed ID: 29095572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Engineering the phosphoinositide-binding profile of a class I pleckstrin homology domain.
    Cozier GE; Bouyoucef D; Cullen PJ
    J Biol Chem; 2003 Oct; 278(41):39489-96. PubMed ID: 12885767
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of Ins(2,4,5)P3-stimulated Ca2+ mobilization by ins(1,3,4, 5)P4: enhancement by activated G-proteins, and evidence for the involvement of a GAP1 protein, a putative Ins(1,3,4,5)P4 receptor.
    Loomis-Husselbee JW; Walker CD; Bottomley JR; Cullen PJ; Irvine RF; Dawson AP
    Biochem J; 1998 May; 331 ( Pt 3)(Pt 3):947-52. PubMed ID: 9560326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. GAP positions catalytic H-Ras residue Q61 for GTP hydrolysis in molecular dynamics simulations, complicating chemical rescue of Ras deactivation.
    Patel LA; Waybright TJ; Stephen AG; Neale C
    Comput Biol Chem; 2023 Jun; 104():107835. PubMed ID: 36893567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.