113 related articles for article (PubMed ID: 19434656)
1. How to achieve confidence in drug discovery and development: managing risk (from a reductionist to a holistic approach).
Bakker A; Caricasole A; Gaviraghi G; Pollio G; Robertson G; Terstappen GC; Salerno M; Tunici P
ChemMedChem; 2009 Jun; 4(6):923-33. PubMed ID: 19434656
[TBL] [Abstract][Full Text] [Related]
2. Alternative strategies in drug development: clinical pharmacological aspects.
Kuhlmann J
Int J Clin Pharmacol Ther; 1999 Dec; 37(12):575-83. PubMed ID: 10599949
[TBL] [Abstract][Full Text] [Related]
3. Towards a more robust approach to selecting and prosecuting promising targets and compounds.
Robertson G
Future Med Chem; 2010 Jan; 2(1):25-34. PubMed ID: 21426044
[TBL] [Abstract][Full Text] [Related]
4. Molecular imaging to biomarker development in neuroscience.
Frost JJ
Ann N Y Acad Sci; 2008 Nov; 1144():251-5. PubMed ID: 19076382
[TBL] [Abstract][Full Text] [Related]
5. Mining and visualizing the chemical content of large databases.
Villar HO; Hansen MR
Curr Opin Drug Discov Devel; 2009 May; 12(3):367-75. PubMed ID: 19396738
[TBL] [Abstract][Full Text] [Related]
6. Opportunities and challenges in the discovery of new central nervous system drugs.
Krause JE; Chenard BL
Ann N Y Acad Sci; 2008 Nov; 1144():243-50. PubMed ID: 19076381
[TBL] [Abstract][Full Text] [Related]
7. Novel trends in high-throughput screening.
Mayr LM; Bojanic D
Curr Opin Pharmacol; 2009 Oct; 9(5):580-8. PubMed ID: 19775937
[TBL] [Abstract][Full Text] [Related]
8. Correct assessment of new compounds using in vivo screening models can reduce false positives.
Bueters TJ; Hoogstraate J; Visser SA
Drug Discov Today; 2009 Jan; 14(1-2):89-94. PubMed ID: 18840543
[TBL] [Abstract][Full Text] [Related]
9. Comparative psychology and the grand challenge of drug discovery in psychiatry and neurodegeneration.
Brunner D; Balcı F; Ludvig EA
Behav Processes; 2012 Feb; 89(2):187-95. PubMed ID: 22155361
[TBL] [Abstract][Full Text] [Related]
10. Challenges in the search for drugs to treat central nervous system disorders.
Enna SJ; Williams M
J Pharmacol Exp Ther; 2009 May; 329(2):404-11. PubMed ID: 19182069
[TBL] [Abstract][Full Text] [Related]
11. Looking forward in pharmaceutical process chemistry.
Davies IW; Welch CJ
Science; 2009 Aug; 325(5941):701-4. PubMed ID: 19661417
[TBL] [Abstract][Full Text] [Related]
12. A role for fMRI in optimizing CNS drug development.
Borsook D; Becerra L; Hargreaves R
Nat Rev Drug Discov; 2006 May; 5(5):411-24. PubMed ID: 16604100
[TBL] [Abstract][Full Text] [Related]
13. Animal models of depression in drug discovery: a historical perspective.
McArthur R; Borsini F
Pharmacol Biochem Behav; 2006 Jul; 84(3):436-52. PubMed ID: 16844210
[TBL] [Abstract][Full Text] [Related]
14. Drug selection in early drug development: screening for acceptable pharmacokinetic properties using combined in vitro and computational approaches.
Sinko PJ
Curr Opin Drug Discov Devel; 1999 Jan; 2(1):42-8. PubMed ID: 19649916
[TBL] [Abstract][Full Text] [Related]
15. Needed: system dynamics for the drug discovery process.
Sirois S; Cloutier LM
Drug Discov Today; 2008 Aug; 13(15-16):708-15. PubMed ID: 18675763
[TBL] [Abstract][Full Text] [Related]
16. Seeing small molecules in action with bioorthogonal chemistry.
Raghavan AS; Hang HC
Drug Discov Today; 2009 Feb; 14(3-4):178-84. PubMed ID: 18973827
[TBL] [Abstract][Full Text] [Related]
17. Optimizing candidate selection--a vision in business limited conference. 1-2 December 1998, Basel, Switzerland.
Audus KL
IDrugs; 1999 Feb; 2(2):91-3. PubMed ID: 16160941
[TBL] [Abstract][Full Text] [Related]
18. The value of drug repositioning in the current pharmaceutical market.
Tobinick EL
Drug News Perspect; 2009 Mar; 22(2):119-25. PubMed ID: 19330170
[TBL] [Abstract][Full Text] [Related]
19. Does human pharmacokinetic prediction add significant value to compound selection in drug discovery research?
Beaumont K; Smith DA
Curr Opin Drug Discov Devel; 2009 Jan; 12(1):61-71. PubMed ID: 19152214
[TBL] [Abstract][Full Text] [Related]
20. Finding new drug targets in the 21st century.
Lindsay MA
Drug Discov Today; 2005 Dec; 10(23-24):1683-7. PubMed ID: 16376829
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
