BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

422 related articles for article (PubMed ID: 19435915)

  • 1. Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer.
    Geismann C; Morscheck M; Koch D; Bergmann F; Ungefroren H; Arlt A; Tsao MS; Bachem MG; Altevogt P; Sipos B; Fölsch UR; Schäfer H; Müerköster SS
    Cancer Res; 2009 May; 69(10):4517-26. PubMed ID: 19435915
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Binding of the transcription factor Slug to the L1CAM promoter is essential for transforming growth factor-β1 (TGF-β)-induced L1CAM expression in human pancreatic ductal adenocarcinoma cells.
    Geismann C; Arlt A; Bauer I; Pfeifer M; Schirmer U; Altevogt P; Müerköster SS; Schäfer H
    Int J Oncol; 2011 Jan; 38(1):257-66. PubMed ID: 21109948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Myofibroblast-induced tumorigenicity of pancreatic ductal epithelial cells is L1CAM dependent.
    Schäfer H; Geismann C; Heneweer C; Egberts JH; Korniienko O; Kiefel H; Moldenhauer G; Bachem MG; Kalthoff H; Altevogt P; Sebens S
    Carcinogenesis; 2012 Jan; 33(1):84-93. PubMed ID: 22095073
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1.
    Genrich G; Kruppa M; Lenk L; Helm O; Broich A; Freitag-Wolf S; Röcken C; Sipos B; Schäfer H; Sebens S
    BMC Cancer; 2016 Feb; 16():155. PubMed ID: 26915435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TGF-β1-dependent L1CAM expression has an essential role in macrophage-induced apoptosis resistance and cell migration of human intestinal epithelial cells.
    Schäfer H; Struck B; Feldmann EM; Bergmann F; Grage-Griebenow E; Geismann C; Ehlers S; Altevogt P; Sebens S
    Oncogene; 2013 Jan; 32(2):180-9. PubMed ID: 22349829
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells.
    Arfmann-Knübel S; Struck B; Genrich G; Helm O; Sipos B; Sebens S; Schäfer H
    PLoS One; 2015; 10(7):e0132978. PubMed ID: 26226105
    [TBL] [Abstract][Full Text] [Related]  

  • 7. alpha5-integrin is crucial for L1CAM-mediated chemoresistance in pancreatic adenocarcinoma.
    Sebens Müerköster S; Kötteritzsch J; Geismann C; Gast D; Kruse ML; Altevogt P; Fölsch UR; Schäfer H
    Int J Oncol; 2009 Jan; 34(1):243-53. PubMed ID: 19082495
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling.
    Ungefroren H; Sebens S; Giehl K; Helm O; Groth S; Fändrich F; Röcken C; Sipos B; Lehnert H; Gieseler F
    Oncotarget; 2014 Jan; 5(1):277-90. PubMed ID: 24378395
    [TBL] [Abstract][Full Text] [Related]  

  • 9. L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression.
    Grage-Griebenow E; Jerg E; Gorys A; Wicklein D; Wesch D; Freitag-Wolf S; Goebel L; Vogel I; Becker T; Ebsen M; Röcken C; Altevogt P; Schumacher U; Schäfer H; Sebens S
    Mol Oncol; 2014 Jul; 8(5):982-97. PubMed ID: 24746181
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TGF-β1 secreted by pancreatic stellate cells promotes stemness and tumourigenicity in pancreatic cancer cells through L1CAM downregulation.
    Cave DD; Di Guida M; Costa V; Sevillano M; Ferrante L; Heeschen C; Corona M; Cucciardi A; Lonardo E
    Oncogene; 2020 May; 39(21):4271-4285. PubMed ID: 32291413
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Extracellular matrix-mediated membrane-type 1 matrix metalloproteinase expression in pancreatic ductal cells is regulated by transforming growth factor-beta1.
    Ottaviano AJ; Sun L; Ananthanarayanan V; Munshi HG
    Cancer Res; 2006 Jul; 66(14):7032-40. PubMed ID: 16849548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells.
    Sebens Müerköster S; Werbing V; Sipos B; Debus MA; Witt M; Grossmann M; Leisner D; Kötteritzsch J; Kappes H; Klöppel G; Altevogt P; Fölsch UR; Schäfer H
    Oncogene; 2007 Apr; 26(19):2759-68. PubMed ID: 17086212
    [TBL] [Abstract][Full Text] [Related]  

  • 13. EMT-associated up-regulation of L1CAM provides insights into L1CAM-mediated integrin signalling and NF-κB activation.
    Kiefel H; Bondong S; Pfeifer M; Schirmer U; Erbe-Hoffmann N; Schäfer H; Sebens S; Altevogt P
    Carcinogenesis; 2012 Oct; 33(10):1919-29. PubMed ID: 22764136
    [TBL] [Abstract][Full Text] [Related]  

  • 14. L1CAM-integrin interaction induces constitutive NF-kappaB activation in pancreatic adenocarcinoma cells by enhancing IL-1beta expression.
    Kiefel H; Bondong S; Erbe-Hoffmann N; Hazin J; Riedle S; Wolf J; Pfeifer M; Arlt A; Schäfer H; Müerköster SS; Altevogt P
    Oncogene; 2010 Aug; 29(34):4766-78. PubMed ID: 20543863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The antioxidant transcription factor Nrf2 modulates the stress response and phenotype of malignant as well as premalignant pancreatic ductal epithelial cells by inducing expression of the ATF3 splicing variant ΔZip2.
    Kha ML; Hesse L; Deisinger F; Sipos B; Röcken C; Arlt A; Sebens S; Helm O; Schäfer H
    Oncogene; 2019 Feb; 38(9):1461-1476. PubMed ID: 30302023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Slug-dependent upregulation of L1CAM is responsible for the increased invasion potential of pancreatic cancer cells following long-term 5-FU treatment.
    Lund K; Dembinski JL; Solberg N; Urbanucci A; Mills IG; Krauss S
    PLoS One; 2015; 10(4):e0123684. PubMed ID: 25860483
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis.
    Helm O; Held-Feindt J; Grage-Griebenow E; Reiling N; Ungefroren H; Vogel I; Krüger U; Becker T; Ebsen M; Röcken C; Kabelitz D; Schäfer H; Sebens S
    Int J Cancer; 2014 Aug; 135(4):843-61. PubMed ID: 24458546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stem cell marker nestin is critical for TGF-β1-mediated tumor progression in pancreatic cancer.
    Su HT; Weng CC; Hsiao PJ; Chen LH; Kuo TL; Chen YW; Kuo KK; Cheng KH
    Mol Cancer Res; 2013 Jul; 11(7):768-79. PubMed ID: 23552743
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1.
    Radke DI; Ungefroren H; Helm O; Voigt S; Alp G; Braun H; Hübner S; Dilchert J; Sebens S; Adam D; Kalthoff H; Trauzold A
    Cell Signal; 2016 Nov; 28(11):1652-62. PubMed ID: 27492861
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action.
    Bartscht T; Rosien B; Rades D; Kaufmann R; Biersack H; Lehnert H; Gieseler F; Ungefroren H
    Mol Cancer; 2015 Nov; 14():199. PubMed ID: 26588899
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.