84 related articles for article (PubMed ID: 19442753)
1. Effect of compound plate composition on measurement of hERG current IC(50) using PatchXpress.
Mo ZL; Faxel T; Yang YS; Gallavan R; Messing D; Bahinski A
J Pharmacol Toxicol Methods; 2009; 60(1):39-44. PubMed ID: 19442753
[TBL] [Abstract][Full Text] [Related]
2. Assessing hERG channel inhibition using PatchXpress.
Ly JQ; Shyy G; Misner DL
Clin Lab Med; 2007 Mar; 27(1):201-8. PubMed ID: 17416313
[TBL] [Abstract][Full Text] [Related]
3. Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 degrees C: Cisapride versus dofetilide.
Milnes JT; Witchel HJ; Leaney JL; Leishman DJ; Hancox JC
J Pharmacol Toxicol Methods; 2010; 61(2):178-91. PubMed ID: 20172036
[TBL] [Abstract][Full Text] [Related]
4. Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation.
Guo L; Guthrie H
J Pharmacol Toxicol Methods; 2005; 52(1):123-35. PubMed ID: 15936217
[TBL] [Abstract][Full Text] [Related]
5. Evaluation of the rubidium efflux assay for preclinical identification of HERG blockade.
Chaudhary KW; O'Neal JM; Mo ZL; Fermini B; Gallavan RH; Bahinski A
Assay Drug Dev Technol; 2006 Feb; 4(1):73-82. PubMed ID: 16506891
[TBL] [Abstract][Full Text] [Related]
6. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
Davie C; Pierre-Valentin J; Pollard C; Standen N; Mitcheson J; Alexander P; Thong B
J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
[TBL] [Abstract][Full Text] [Related]
7. Improved throughput of PatchXpress hERG assay using intracellular potassium fluoride.
Zeng H; Penniman JR; Kinose F; Kim D; Trepakova ES; Malik MG; Dech SJ; Balasubramanian B; Salata JJ
Assay Drug Dev Technol; 2008 Apr; 6(2):235-41. PubMed ID: 18471077
[TBL] [Abstract][Full Text] [Related]
8. Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment.
Brinkwirth N; Takasuna K; Doi M; Becker N; Obergrussberger A; Friis S; Furukawa H; Hasegawa Y; Oka T; Ohtsuki A; Fertig N; Stoelzle-Feix S
J Pharmacol Toxicol Methods; 2020 Sep; 105():106884. PubMed ID: 32565325
[TBL] [Abstract][Full Text] [Related]
9. Application of PatchXpress planar patch clamp technology to the screening of new drug candidates for cardiac KCNQ1/KCNE1 (I Ks) activity.
Trepakova ES; Malik MG; Imredy JP; Penniman JR; Dech SJ; Salata JJ
Assay Drug Dev Technol; 2007 Oct; 5(5):617-27. PubMed ID: 17939752
[TBL] [Abstract][Full Text] [Related]
10. Identifying modulators of hERG channel activity using the PatchXpress planar patch clamp.
Dubin AE; Nasser N; Rohrbacher J; Hermans AN; Marrannes R; Grantham C; Van Rossem K; Cik M; Chaplan SR; Gallacher D; Xu J; Guia A; Byrne NG; Mathes C
J Biomol Screen; 2005 Mar; 10(2):168-81. PubMed ID: 15799960
[TBL] [Abstract][Full Text] [Related]
11. The [3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K+]o.
Diaz GJ; Daniell K; Leitza ST; Martin RL; Su Z; McDermott JS; Cox BF; Gintant GA
J Pharmacol Toxicol Methods; 2004; 50(3):187-99. PubMed ID: 15519905
[TBL] [Abstract][Full Text] [Related]
12. A pharmacologically validated, high-capacity, functional thallium flux assay for the human Ether-à-go-go related gene potassium channel.
Schmalhofer WA; Swensen AM; Thomas BS; Felix JP; Haedo RJ; Solly K; Kiss L; Kaczorowski GJ; Garcia ML
Assay Drug Dev Technol; 2010 Dec; 8(6):714-26. PubMed ID: 21158686
[TBL] [Abstract][Full Text] [Related]
13. Comparison of human Ether-à-go-go related gene screening assays based on IonWorks Quattro and thallium flux.
Bridal TR; Margulis M; Wang X; Donio M; Sorota S
Assay Drug Dev Technol; 2010 Dec; 8(6):755-65. PubMed ID: 20658944
[TBL] [Abstract][Full Text] [Related]
14. Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.
Limberis JT; Su Z; Cox BF; Gintant GA; Martin RL
Clin Exp Pharmacol Physiol; 2006 Nov; 33(11):1059-65. PubMed ID: 17042915
[TBL] [Abstract][Full Text] [Related]
15. IonFlux: a microfluidic patch clamp system evaluated with human Ether-à-go-go related gene channel physiology and pharmacology.
Golden AP; Li N; Chen Q; Lee T; Nevill T; Cao X; Johnson J; Erdemli G; Ionescu-Zanetti C; Urban L; Holmqvist M
Assay Drug Dev Technol; 2011 Dec; 9(6):608-19. PubMed ID: 21561375
[TBL] [Abstract][Full Text] [Related]
16. Interactions at human ether-à-go-go-related gene channels.
Friemel A; Zünkler BJ
Toxicol Sci; 2010 Apr; 114(2):346-55. PubMed ID: 20071423
[TBL] [Abstract][Full Text] [Related]
17. Utility of frozen cell lines in medium throughput electrophysiology screening of hERG and NaV1.5 blockade.
Donovan BT; Bakshi T; Galbraith SE; Nixon CJ; Payne LA; Martens SF
J Pharmacol Toxicol Methods; 2011; 64(3):269-76. PubMed ID: 21996251
[TBL] [Abstract][Full Text] [Related]
18. Differential effects of human ether-a-go-go-related gene (HERG) blocking agents on QT duration variability in conscious dogs.
Schneider J; Hauser R; Andreas JO; Linz K; Jahnel U
Eur J Pharmacol; 2005 Apr; 512(1):53-60. PubMed ID: 15814090
[TBL] [Abstract][Full Text] [Related]
19. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
Dong DL; Li Z; Wang HZ; Du ZM; Song WH; Yang BF
Basic Clin Pharmacol Toxicol; 2004 May; 94(5):209-12. PubMed ID: 15125690
[TBL] [Abstract][Full Text] [Related]
20. Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel.
Singleton DH; Boyd H; Steidl-Nichols JV; Deacon M; Groot MJ; Price D; Nettleton DO; Wallace NK; Troutman MD; Williams C; Boyd JG
J Med Chem; 2007 Jun; 50(13):2931-41. PubMed ID: 17536794
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
