BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 19444798)

  • 1. A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its application to in vitro CYP2D6 and CYP3A4 inhibition study.
    Spanakis M; Vizirianakis IS; Mironidou-Tzouveleki M; Niopas I
    Biomed Chromatogr; 2009 Nov; 23(11):1131-7. PubMed ID: 19444798
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A sensitive LC-MS/MS assay for the determination of dextromethorphan and metabolites in human urine--application for drug interaction studies assessing potential CYP3A and CYP2D6 inhibition.
    Vengurlekar SS; Heitkamp J; McCush F; Velagaleti PR; Brisson JH; Bramer SL
    J Pharm Biomed Anal; 2002 Aug; 30(1):113-24. PubMed ID: 12151071
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of dextromethorphan in rat everted gut sacs.
    Arellano C; Philibert C; Dane à Yakan EN; Vachoux C; Lacombe O; Woodley J; Houin G
    J Chromatogr B Analyt Technol Biomed Life Sci; 2005 May; 819(1):105-13. PubMed ID: 15797528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CTP2D6 and CYP3A activities?
    Yu A; Haining RL
    Drug Metab Dispos; 2001 Nov; 29(11):1514-20. PubMed ID: 11602530
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-performance liquid chromatography assay for simultaneous determination of dextromethorphan and its main metabolites in urine and in microsomal preparations.
    Bendriss EK; Markoglou N; Wainer IW
    J Chromatogr B Biomed Sci Appl; 2001 Apr; 754(1):209-15. PubMed ID: 11318417
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation.
    Jones DR; Gorski JC; Haehner BD; O'Mara EM; Hall SD
    Clin Pharmacol Ther; 1996 Oct; 60(4):374-84. PubMed ID: 8873685
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.
    Al-Jenoobi FI; Al-Thukair AA; Abbas FA; Ansari MJ; Alkharfy KM; Al-Mohizea AM; Al-Suwayeh SA; Jamil S
    Drug Metab Lett; 2010 Jan; 4(1):51-5. PubMed ID: 20201775
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Automated determination of dextromethorphan and its main metabolites in human plasma by high-performance liquid chromatography and column switching.
    Härtter S; Baier D; Dingemanse J; Ziegler G; Hiemke C
    Ther Drug Monit; 1996 Jun; 18(3):297-303. PubMed ID: 8738772
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simultaneous analysis of dextromethorphan and its three metabolites in human plasma using an improved HPLC method with fluorometric detection.
    Lin SY; Chen CH; Ho HO; Chen HH; Sheu MT
    J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Nov; 859(1):141-6. PubMed ID: 17919999
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry.
    Loos WJ; de Graan AJ; de Bruijn P; van Schaik RH; van Fessem MA; Lam MH; Mathijssen RH; Wiemer EA
    J Pharm Biomed Anal; 2011 Jan; 54(2):387-94. PubMed ID: 20926215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetics and polymorphic oxidation of dextromethorphan in a Japanese population.
    Nagai N; Kawakubo T; Kaneko F; Ishii M; Shinohara R; Saito Y; Shimamura H; Ohnishi A; Ogata H
    Biopharm Drug Dispos; 1996 Jul; 17(5):421-33. PubMed ID: 8830977
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacokinetics of dextromethorphan and its metabolites in horses following a single oral administration.
    Corado CR; McKemie DS; Knych HK
    Drug Test Anal; 2017 Jun; 9(6):880-887. PubMed ID: 27580591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous determination of dextromethorphan and three metabolites in plasma and urine using high-performance liquid chromatography with application to their disposition in man.
    Chen ZR; Somogyi AA; Bochner F
    Ther Drug Monit; 1990 Jan; 12(1):97-104. PubMed ID: 2305428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Simple chromatography method for simultaneous determination of dextromethorphan and its main metabolites in human plasma with fluorimetric detection.
    Afshar M; Rouini MR; Amini M
    J Chromatogr B Analyt Technol Biomed Life Sci; 2004 Apr; 802(2):317-22. PubMed ID: 15018793
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.
    Schmider J; Greenblatt DJ; Fogelman SM; von Moltke LL; Shader RI
    Biopharm Drug Dispos; 1997 Apr; 18(3):227-40. PubMed ID: 9113345
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development and validation of ELISA and GC-MS procedures for the quantification of dextromethorphan and its main metabolite dextrorphan in urine and oral fluid.
    Rodrigues WC; Wang G; Moore C; Agrawal A; Vincent MJ; Soares JR
    J Anal Toxicol; 2008 Apr; 32(3):220-6. PubMed ID: 18397573
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quantification of dextromethorphan and metabolites: a dual phenotypic marker for cytochrome P450 3A4/5 and 2D6 activity.
    Jones DR; Gorski JC; Hamman MA; Hall SD
    J Chromatogr B Biomed Appl; 1996 Mar; 678(1):105-11. PubMed ID: 8861660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sex differences in 3,4-methylenedioxymethamphetamine (MDMA; ecstasy)-induced cytochrome P450 2D6 inhibition in humans.
    Yubero-Lahoz S; Pardo R; Farré M; O'Mahony B; Torrens M; Mustata C; Pérez-Mañá C; Carbó ML; de la Torre R
    Clin Pharmacokinet; 2011 May; 50(5):319-29. PubMed ID: 21456632
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Liquid chromatography/tandem mass spectrometry method for simultaneous evaluation of activities of five cytochrome P450s using a five-drug cocktail and application to cytochrome P450 phenotyping studies in rats.
    Zhang S; Song N; Li Q; Fan H; Liu C
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Aug; 871(1):78-89. PubMed ID: 18614408
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of Curcuma longa on CYP2D6- and CYP3A4-mediated metabolism of dextromethorphan in human liver microsomes and healthy human subjects.
    Al-Jenoobi FI; Al-Thukair AA; Alam MA; Abbas FA; Al-Mohizea AM; Alkharfy KM; Al-Suwayeh SA
    Eur J Drug Metab Pharmacokinet; 2015 Mar; 40(1):61-6. PubMed ID: 24510399
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.