BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 19445902)

  • 41. The effect of cimetidine on dextromethorphan O-demethylase activity of human liver microsomes and recombinant CYP2D6.
    Madeira M; Levine M; Chang TK; Mirfazaelian A; Bellward GD
    Drug Metab Dispos; 2004 Apr; 32(4):460-7. PubMed ID: 16680870
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Results and challenges of Cytochrome P450 2D6 (CYP2D6) testing in an ethnically diverse South Florida population.
    Salyakina D; Roy S; Wang W; Oliva M; Akhouri R; Sotto I; Mulas N; Solano R; Fernández JR; Sanchez S; Shamshad U; Perlyn C; McCafferty-Fernandez J
    Mol Genet Genomic Med; 2019 Sep; 7(9):e922. PubMed ID: 31389673
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Physiologically based pharmacokinetic modelling to predict the pharmacokinetics of metoprolol in different CYP2D6 genotypes.
    Lee CM; Kang P; Cho CK; Park HJ; Lee YJ; Bae JW; Choi CI; Kim HS; Jang CG; Lee SY
    Arch Pharm Res; 2022 Jun; 45(6):433-445. PubMed ID: 35763157
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Challenges in CYP2D6 phenotype assignment from genotype data: a critical assessment and call for standardization.
    Hicks JK; Swen JJ; Gaedigk A
    Curr Drug Metab; 2014 Feb; 15(2):218-32. PubMed ID: 24524666
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism.
    Sauer JM; Ponsler GD; Mattiuz EL; Long AJ; Witcher JW; Thomasson HR; Desante KA
    Drug Metab Dispos; 2003 Jan; 31(1):98-107. PubMed ID: 12485958
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone.
    Samer CF; Daali Y; Wagner M; Hopfgartner G; Eap CB; Rebsamen MC; Rossier MF; Hochstrasser D; Dayer P; Desmeules JA
    Br J Pharmacol; 2010 Jun; 160(4):907-18. PubMed ID: 20590587
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Polymorphic hydroxylation of perhexiline in vitro.
    Sørensen LB; Sørensen RN; Miners JO; Somogyi AA; Grgurinovich N; Birkett DJ
    Br J Clin Pharmacol; 2003 Jun; 55(6):635-8. PubMed ID: 12814462
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Functional analysis of CYP2D6.31 variant: homology modeling suggests possible disruption of redox partner interaction by Arg440His substitution.
    Allorge D; Bréant D; Harlow J; Chowdry J; Lo-Guidice JM; Chevalier D; Cauffiez C; Lhermitte M; Blaney FE; Tucker GT; Broly F; Ellis SW
    Proteins; 2005 May; 59(2):339-46. PubMed ID: 15726636
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Complex disease-, gene-, and drug-drug interactions: impacts of renal function, CYP2D6 phenotype, and OCT2 activity on veliparib pharmacokinetics.
    Li J; Kim S; Sha X; Wiegand R; Wu J; LoRusso P
    Clin Cancer Res; 2014 Aug; 20(15):3931-44. PubMed ID: 24947923
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Identification of the human cytochromes P450 responsible for atomoxetine metabolism.
    Ring BJ; Gillespie JS; Eckstein JA; Wrighton SA
    Drug Metab Dispos; 2002 Mar; 30(3):319-23. PubMed ID: 11854152
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Standardizing CYP2D6 Genotype to Phenotype Translation: Consensus Recommendations from the Clinical Pharmacogenetics Implementation Consortium and Dutch Pharmacogenetics Working Group.
    Caudle KE; Sangkuhl K; Whirl-Carrillo M; Swen JJ; Haidar CE; Klein TE; Gammal RS; Relling MV; Scott SA; Hertz DL; Guchelaar HJ; Gaedigk A
    Clin Transl Sci; 2020 Jan; 13(1):116-124. PubMed ID: 31647186
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Impact of CYP2D6 Genetic Variation on the Response of the Cardiovascular Patient to Carvedilol and Metoprolol.
    Lymperopoulos A; McCrink KA; Brill A
    Curr Drug Metab; 2015; 17(1):30-6. PubMed ID: 26537419
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Potential role of CYP2D6 in the central nervous system.
    Cheng J; Zhen Y; Miksys S; Beyoğlu D; Krausz KW; Tyndale RF; Yu A; Idle JR; Gonzalez FJ
    Xenobiotica; 2013 Nov; 43(11):973-84. PubMed ID: 23614566
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation.
    de Leon J; Susce MT; Pan RM; Fairchild M; Koch WH; Wedlund PJ
    J Clin Psychiatry; 2005 Jan; 66(1):15-27. PubMed ID: 15669884
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Cytochrome P450 expression and regulation in CYP3A4/CYP2D6 double transgenic humanized mice.
    Felmlee MA; Lon HK; Gonzalez FJ; Yu AM
    Drug Metab Dispos; 2008 Feb; 36(2):435-41. PubMed ID: 18048490
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Cytochrome P
    Dhuya M; Pal MM; Hazra A; Chatterjee S; Gogtay N
    Indian J Pharmacol; 2020; 52(3):189-195. PubMed ID: 32874001
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Pharmacogenetics of classical and new antipsychotic drugs.
    Otani K; Aoshima T
    Ther Drug Monit; 2000 Feb; 22(1):118-21. PubMed ID: 10688273
    [TBL] [Abstract][Full Text] [Related]  

  • 58. CYP2D6 polymorphism and clinical effect of the antidepressant venlafaxine.
    Shams ME; Arneth B; Hiemke C; Dragicevic A; Müller MJ; Kaiser R; Lackner K; Härtter S
    J Clin Pharm Ther; 2006 Oct; 31(5):493-502. PubMed ID: 16958828
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
    Staack RF; Theobald DS; Paul LD; Springer D; Kraemer T; Maurer HH
    Drug Metab Dispos; 2004 Apr; 32(4):379-81. PubMed ID: 15039289
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Development of a PCR-based strategy for CYP2D6 genotyping including gene multiplication of worldwide potential use.
    Dorado P; Cáceres MC; Pozo-Guisado E; Wong ML; Licinio J; Llerena A
    Biotechniques; 2005 Oct; 39(4):571-4. PubMed ID: 16235570
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.