277 related articles for article (PubMed ID: 19446241)
1. In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates.
Olaharski AJ; Uppal H; Cooper M; Platz S; Zabka TS; Kolaja KL
Toxicol Lett; 2009 Jul; 188(2):98-103. PubMed ID: 19446241
[TBL] [Abstract][Full Text] [Related]
2. Validation and development of a predictive paradigm for hemotoxicology using a multifunctional bioluminescence colony-forming proliferation assay.
Rich IN; Hall KM
Toxicol Sci; 2005 Oct; 87(2):427-41. PubMed ID: 16002476
[TBL] [Abstract][Full Text] [Related]
3. High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening.
O'Brien PJ; Irwin W; Diaz D; Howard-Cofield E; Krejsa CM; Slaughter MR; Gao B; Kaludercic N; Angeline A; Bernardi P; Brain P; Hougham C
Arch Toxicol; 2006 Sep; 80(9):580-604. PubMed ID: 16598496
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of the Vitotox and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development.
Westerink WM; Stevenson JC; Lauwers A; Griffioen G; Horbach GJ; Schoonen WG
Mutat Res; 2009 May; 676(1-2):113-30. PubMed ID: 19393335
[TBL] [Abstract][Full Text] [Related]
5. Application of human CFU-Mk assay to predict potential thrombocytotoxicity of drugs.
Pessina A; Parent-Massin D; Albella B; Van Den Heuvel R; Casati S; Croera C; Malerba I; Sibiril Y; Gomez S; de Smedt A; Gribaldo L
Toxicol In Vitro; 2009 Feb; 23(1):194-200. PubMed ID: 19084588
[TBL] [Abstract][Full Text] [Related]
6. High-throughput in vitro hemotoxicity testing and in vitro cross-platform comparative toxicity.
Rich IN
Expert Opin Drug Metab Toxicol; 2007 Apr; 3(2):295-307. PubMed ID: 17428158
[TBL] [Abstract][Full Text] [Related]
7. In vitro sensitivity of granulo-monocytic progenitors as a new toxicological cell system and endpoint in the ACuteTox Project.
Cerrato L; Valeri A; Bueren JA; Albella B
Toxicol Appl Pharmacol; 2009 Jul; 238(2):111-9. PubMed ID: 19442680
[TBL] [Abstract][Full Text] [Related]
8. Assessment of the Embryonic Stem Cell Test and application and use in the pharmaceutical industry.
Paquette JA; Kumpf SW; Streck RD; Thomson JJ; Chapin RE; Stedman DB
Birth Defects Res B Dev Reprod Toxicol; 2008 Apr; 83(2):104-11. PubMed ID: 18361453
[TBL] [Abstract][Full Text] [Related]
9. A new experimental protocol as an alternative to the colony-forming unit-granulocyte/macrophage (CFU-GM) clonogenic assay to assess the haematotoxic potential of new drugs.
Dal Negro G; Vandin L; Bonato M; Repeto P; Sciuscio D
Toxicol In Vitro; 2006 Aug; 20(5):750-6. PubMed ID: 16321498
[TBL] [Abstract][Full Text] [Related]
10. Correlation of hematologic toxicity of antineoplastic agents with their effects on bone marrow stem cells: interspecies studies using an in vivo assay.
Marsh JC
Exp Hematol; 1985; 13 Suppl 16():16-22. PubMed ID: 3987835
[TBL] [Abstract][Full Text] [Related]
11. High-content micronucleus assay in genotoxicity profiling: initial-stage development and some applications in the investigative/lead-finding studies in drug discovery.
Mondal MS; Gabriels J; McGinnis C; Magnifico M; Marsilje TH; Urban L; Collis A; Bojanic D; Biller SA; Frieauff W; Martus HJ; Suter W; Bentley P
Toxicol Sci; 2010 Nov; 118(1):71-85. PubMed ID: 20631060
[TBL] [Abstract][Full Text] [Related]
12. In vitro detection of drug-induced phospholipidosis using gene expression and fluorescent phospholipid based methodologies.
Nioi P; Perry BK; Wang EJ; Gu YZ; Snyder RD
Toxicol Sci; 2007 Sep; 99(1):162-73. PubMed ID: 17567588
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of CFU-E/BFU-E and CFU-GM colony growth by cyclophosphamide, 5-fluorouracil and taxol: development of a high-throughput in vitro method.
Malerba I; Casati S; Diodovich C; Parent-Massin D; Gribaldo L
Toxicol In Vitro; 2004 Jun; 18(3):293-300. PubMed ID: 15046776
[TBL] [Abstract][Full Text] [Related]
14. Refinement of the colony-forming unit-megakaryocyte (CFU-MK) assay for its application to pharmaco-toxicological testing.
Casati S; Collotta A; Clothier R; Gribaldo L
Toxicol In Vitro; 2003 Feb; 17(1):69-75. PubMed ID: 12537964
[TBL] [Abstract][Full Text] [Related]
15. High-specificity and high-sensitivity genotoxicity assessment in a human cell line: validation of the GreenScreen HC GADD45a-GFP genotoxicity assay.
Hastwell PW; Chai LL; Roberts KJ; Webster TW; Harvey JS; Rees RW; Walmsley RM
Mutat Res; 2006 Sep; 607(2):160-75. PubMed ID: 16781187
[TBL] [Abstract][Full Text] [Related]
16. Research perspectives for pre-screening alternatives to animal experimentation: on the relevance of cytotoxicity measurements, barrier passage determinations and high throughput screening in vitro to select potentially hazardous compounds in large sets of chemicals.
Walum E; Hedander J; Garberg P
Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):393-7. PubMed ID: 15982691
[TBL] [Abstract][Full Text] [Related]
17. In vitro bone marrow granulocyte-macrophage progenitor cultures in the assessment of hematotoxic potential of the new drugs.
Negro GD; Bonato M; Gribaldo L
Cell Biol Toxicol; 2001; 17(2):95-105. PubMed ID: 11499700
[TBL] [Abstract][Full Text] [Related]
18. Application of a high-content multiparameter cytotoxicity assay to prioritize compounds based on toxicity potential in humans.
Abraham VC; Towne DL; Waring JF; Warrior U; Burns DJ
J Biomol Screen; 2008 Jul; 13(6):527-37. PubMed ID: 18566484
[TBL] [Abstract][Full Text] [Related]
19. Determination of cell colony formation in a high-content screening assay.
Wylie PG; Bowen WP
Clin Lab Med; 2007 Mar; 27(1):193-9. PubMed ID: 17416312
[TBL] [Abstract][Full Text] [Related]
20. Screening for phospholipidosis induced by central nervous drugs: comparing the predictivity of an in vitro assay to high throughput in silico assays.
Mesens N; Steemans M; Hansen E; Verheyen GR; Van Goethem F; Van Gompel J
Toxicol In Vitro; 2010 Aug; 24(5):1417-25. PubMed ID: 20430096
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]