324 related articles for article (PubMed ID: 19446432)
1. What have we learned from pre-clinical juvenile toxicity studies?
Bailey GP; Mariën D
Reprod Toxicol; 2009 Sep; 28(2):226-9. PubMed ID: 19446432
[TBL] [Abstract][Full Text] [Related]
2. Real life juvenile toxicity case studies: the good, the bad and the ugly.
De Schaepdrijver L; Rouan MC; Raoof A; Bailey GP; De Zwart L; Monbaliu J; Coogan TP; Lammens L; Coussement W
Reprod Toxicol; 2008 Sep; 26(1):54-5. PubMed ID: 18514481
[TBL] [Abstract][Full Text] [Related]
3. Juvenile animal toxicity study designs to support pediatric drug development.
Cappon GD; Bailey GP; Buschmann J; Feuston MH; Fisher JE; Hew KW; Hoberman AM; Ooshima Y; Stump DG; Hurtt ME
Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):463-9. PubMed ID: 20025047
[TBL] [Abstract][Full Text] [Related]
4. The value of juvenile animal studies "What have we learned from preclinical juvenile toxicity studies? II".
Bailey GP; Mariën D
Birth Defects Res B Dev Reprod Toxicol; 2011 Aug; 92(4):273-91. PubMed ID: 22623019
[TBL] [Abstract][Full Text] [Related]
5. Optimising the design of preliminary toxicity studies for pharmaceutical safety testing in the dog.
Smith D; Combes R; Depelchin O; Jacobsen SD; Hack R; Luft J; Lammens L; von Landenberg F; Phillips B; Pfister R; Rabemampianina Y; Sparrow S; Stark C; Stephan-Gueldner M
Regul Toxicol Pharmacol; 2005 Mar; 41(2):95-101. PubMed ID: 15698532
[TBL] [Abstract][Full Text] [Related]
6. High dose selection in general toxicity studies for drug development: A pharmaceutical industry perspective.
Buckley LA; Dorato MA
Regul Toxicol Pharmacol; 2009 Aug; 54(3):301-7. PubMed ID: 19477212
[TBL] [Abstract][Full Text] [Related]
7. Evaluations of organ system development in juvenile toxicology testing.
Robinson K
Reprod Toxicol; 2008 Sep; 26(1):51-3. PubMed ID: 18595655
[TBL] [Abstract][Full Text] [Related]
8. Safety evaluation to support First-In-Man investigations II: toxicology studies.
Baldrick P
Regul Toxicol Pharmacol; 2008 Jul; 51(2):237-43. PubMed ID: 18501490
[TBL] [Abstract][Full Text] [Related]
9. A European pharmaceutical company initiative challenging the regulatory requirement for acute toxicity studies in pharmaceutical drug development.
Robinson S; Delongeas JL; Donald E; Dreher D; Festag M; Kervyn S; Lampo A; Nahas K; Nogues V; Ockert D; Quinn K; Old S; Pickersgill N; Somers K; Stark C; Stei P; Waterson L; Chapman K
Regul Toxicol Pharmacol; 2008 Apr; 50(3):345-52. PubMed ID: 18295384
[TBL] [Abstract][Full Text] [Related]
10. Pre- and postnatal developmental toxicity study design for pharmaceuticals.
Bailey GP; Wise LD; Buschmann J; Hurtt M; Fisher JE
Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):437-45. PubMed ID: 20025040
[TBL] [Abstract][Full Text] [Related]
11. Embryo-fetal developmental toxicity study design for pharmaceuticals.
Wise LD; Buschmann J; Feuston MH; Fisher JE; Hew KW; Hoberman AM; Lerman SA; Ooshima Y; Stump DG
Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):418-28. PubMed ID: 20025038
[TBL] [Abstract][Full Text] [Related]
12. Safety evaluation to support First-In-Man investigations I: kinetic and safety pharmacology studies.
Baldrick P
Regul Toxicol Pharmacol; 2008 Jul; 51(2):230-6. PubMed ID: 18501489
[TBL] [Abstract][Full Text] [Related]
13. Juvenile toxicity: are we asking the right questions?
Downes N
Toxicol Pathol; 2012 Jul; 40(5):830-7. PubMed ID: 22407308
[TBL] [Abstract][Full Text] [Related]
14. In silico methods for early toxicity assessment.
Merlot C
Curr Opin Drug Discov Devel; 2008 Jan; 11(1):80-5. PubMed ID: 18175270
[TBL] [Abstract][Full Text] [Related]
15. A search to predict potential for drug-induced cardiovascular toxicity.
Hamlin RL
Toxicol Pathol; 2006; 34(1):75-80. PubMed ID: 16507547
[TBL] [Abstract][Full Text] [Related]
16. Introduction to special issue on developmental and reproductive toxicity study designs for pharmaceuticals.
Wise LD
Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):417. PubMed ID: 20025037
[No Abstract] [Full Text] [Related]
17. The nonclinical fertility study design for pharmaceuticals.
Lerman SA; Hew KW; Stewart J; Stump DG; Wise LD
Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):429-36. PubMed ID: 20025039
[TBL] [Abstract][Full Text] [Related]
18. Immune function tests for hazard identification: a paradigm shift in drug development.
Gore ER
Basic Clin Pharmacol Toxicol; 2006 Apr; 98(4):331-5. PubMed ID: 16623854
[TBL] [Abstract][Full Text] [Related]
19. Integrating metabolism and toxicity in multi-organ systems.
Madden S; Bach PH
Curr Opin Drug Discov Devel; 2001 Jan; 4(1):66-72. PubMed ID: 11727325
[TBL] [Abstract][Full Text] [Related]
20. Single dose toxicity and repeated dose toxicity studies: introductory remarks.
Kurokawa Y; Matsuzawa T
J Toxicol Sci; 1996 Dec; 21(5):413-6. PubMed ID: 9035047
[No Abstract] [Full Text] [Related]
[Next] [New Search]