994 related articles for article (PubMed ID: 19446730)
1. Modeling small molecule-compound binding to G-protein-coupled receptors.
Vaidehi N; Pease JE; Horuk R
Methods Enzymol; 2009; 460():263-88. PubMed ID: 19446730
[TBL] [Abstract][Full Text] [Related]
2. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
Bhattacharya S; Hall SE; Vaidehi N
J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
[TBL] [Abstract][Full Text] [Related]
3. Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function.
Kristiansen K
Pharmacol Ther; 2004 Jul; 103(1):21-80. PubMed ID: 15251227
[TBL] [Abstract][Full Text] [Related]
4. Dynamics and flexibility of G-protein-coupled receptor conformations and their relevance to drug design.
Vaidehi N
Drug Discov Today; 2010 Nov; 15(21-22):951-7. PubMed ID: 20831898
[TBL] [Abstract][Full Text] [Related]
5. Rough set-based proteochemometrics modeling of G-protein-coupled receptor-ligand interactions.
Strömbergsson H; Prusis P; Midelfart H; Lapinsh M; Wikberg JE; Komorowski J
Proteins; 2006 Apr; 63(1):24-34. PubMed ID: 16435365
[TBL] [Abstract][Full Text] [Related]
6. PREDICT modeling and in-silico screening for G-protein coupled receptors.
Shacham S; Marantz Y; Bar-Haim S; Kalid O; Warshaviak D; Avisar N; Inbal B; Heifetz A; Fichman M; Topf M; Naor Z; Noiman S; Becker OM
Proteins; 2004 Oct; 57(1):51-86. PubMed ID: 15326594
[TBL] [Abstract][Full Text] [Related]
7. Activation of G protein-coupled receptors.
Deupi X; Kobilka B
Adv Protein Chem; 2007; 74():137-66. PubMed ID: 17854657
[TBL] [Abstract][Full Text] [Related]
8. Conformational complexity of G-protein-coupled receptors.
Kobilka BK; Deupi X
Trends Pharmacol Sci; 2007 Aug; 28(8):397-406. PubMed ID: 17629961
[TBL] [Abstract][Full Text] [Related]
9. Structural diversity of G protein-coupled receptors and significance for drug discovery.
Lagerström MC; Schiöth HB
Nat Rev Drug Discov; 2008 Apr; 7(4):339-57. PubMed ID: 18382464
[TBL] [Abstract][Full Text] [Related]
10. Recognition of GPCRs by peptide ligands and membrane compartments theory: structural studies of endogenous peptide hormones in membrane environment.
Sankararamakrishnan R
Biosci Rep; 2006 Apr; 26(2):131-58. PubMed ID: 16773462
[TBL] [Abstract][Full Text] [Related]
11. Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening.
Klabunde T; Giegerich C; Evers A
J Med Chem; 2009 May; 52(9):2923-32. PubMed ID: 19374402
[TBL] [Abstract][Full Text] [Related]
12. Ligand-steered modeling and docking: A benchmarking study in class A G-protein-coupled receptors.
Phatak SS; Gatica EA; Cavasotto CN
J Chem Inf Model; 2010 Dec; 50(12):2119-28. PubMed ID: 21080692
[TBL] [Abstract][Full Text] [Related]
13. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
Heilker R; Wolff M; Tautermann CS; Bieler M
Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411
[TBL] [Abstract][Full Text] [Related]
14. Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics.
Gilchrist A
Trends Pharmacol Sci; 2007 Aug; 28(8):431-7. PubMed ID: 17644194
[TBL] [Abstract][Full Text] [Related]
15. Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors.
Wheatley M; Simms J; Hawtin SR; Wesley VJ; Wootten D; Conner M; Lawson Z; Conner AC; Baker A; Cashmore Y; Kendrick R; Parslow RA
Biochem Soc Trans; 2007 Aug; 35(Pt 4):717-20. PubMed ID: 17635132
[TBL] [Abstract][Full Text] [Related]
16. Drug design strategies for targeting G-protein-coupled receptors.
Klabunde T; Hessler G
Chembiochem; 2002 Oct; 3(10):928-44. PubMed ID: 12362358
[TBL] [Abstract][Full Text] [Related]
17. I want a new drug: G-protein-coupled receptors in drug development.
Schlyer S; Horuk R
Drug Discov Today; 2006 Jun; 11(11-12):481-93. PubMed ID: 16713899
[TBL] [Abstract][Full Text] [Related]
18. Orthosteric/allosteric bitopic ligands: going hybrid at GPCRs.
Valant C; Sexton PM; Christopoulos A
Mol Interv; 2009 Jun; 9(3):125-35. PubMed ID: 19592673
[TBL] [Abstract][Full Text] [Related]
19. GLIDA: GPCR-ligand database for chemical genomic drug discovery.
Okuno Y; Yang J; Taneishi K; Yabuuchi H; Tsujimoto G
Nucleic Acids Res; 2006 Jan; 34(Database issue):D673-7. PubMed ID: 16381956
[TBL] [Abstract][Full Text] [Related]
20. Dimerization and oligomerization of G-protein-coupled receptors: debated structures with established and emerging functions.
Szidonya L; Cserzo M; Hunyady L
J Endocrinol; 2008 Mar; 196(3):435-53. PubMed ID: 18310440
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
