BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

564 related articles for article (PubMed ID: 19447184)

  • 1. Measuring the risk of torsades de pointes: electrocardiographic evaluation of PNU-142093 in conscious cynomolgus non-human primates using restraint and non-restraint procedures.
    Bass AS; Hanson LA; Jackson TA
    J Pharmacol Toxicol Methods; 2009; 60(1):51-7. PubMed ID: 19447184
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Detection of QTc interval prolongation using jacket telemetry in conscious non-human primates: comparison with implanted telemetry.
    Derakhchan K; Chui RW; Stevens D; Gu W; Vargas HM
    Br J Pharmacol; 2014 Jan; 171(2):509-22. PubMed ID: 24372552
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of group housing on ECG assessment in conscious cynomolgus monkeys.
    Xing G; Lu J; Hu M; Wang S; Zhao L; Zheng W; Schofield J; Oldman K; Adkins D; Yu H; Platz S; Ren J; Skinner M
    J Pharmacol Toxicol Methods; 2015; 75():44-51. PubMed ID: 25979821
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A highly sensitive canine telemetry model for detection of QT interval prolongation: studies with moxifloxacin, haloperidol and MK-499.
    Chaves AA; Zingaro GJ; Yordy MA; Bustard KA; O'Sullivan S; Galijatovic-Idrizbegovic A; Schuck H; Christian DB; Hoe CM; Briscoe RJ
    J Pharmacol Toxicol Methods; 2007; 56(2):103-14. PubMed ID: 17643323
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cardiovascular monkey telemetry: sensitivity to detect QT interval prolongation.
    Chaves AA; Keller WJ; O'Sullivan S; Williams MA; Fitzgerald LE; McPherson HE; Goykhman D; Ward PD; Hoe CM; Mixson L; Briscoe RJ
    J Pharmacol Toxicol Methods; 2006; 54(2):150-8. PubMed ID: 16679034
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Uni- or bi-ventricular hypertrophy and susceptibility to drug-induced torsades de pointes.
    Panyasing Y; Kijtawornrat A; Del Rio C; Carnes C; Hamlin RL
    J Pharmacol Toxicol Methods; 2010; 62(2):148-56. PubMed ID: 20435152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of a probabilistic method for the determination of drug-induced QT prolongation in telemetered cynomolgus monkeys: effects of moxifloxacin.
    Holzgrefe HH; Cavero I; Buchanan LV; Gill MW; Durham SK
    J Pharmacol Toxicol Methods; 2007; 55(3):227-37. PubMed ID: 17097307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Correction of QT values to allow for increases in heart rate in conscious Beagle dogs in toxicology assessment.
    Tattersall ML; Dymond M; Hammond T; Valentin JP
    J Pharmacol Toxicol Methods; 2006; 53(1):11-9. PubMed ID: 15886026
    [TBL] [Abstract][Full Text] [Related]  

  • 9. QT interval prolongation and the risk of torsades de pointes: essentials for clinicians.
    Trinkley KE; Page RL; Lien H; Yamanouye K; Tisdale JE
    Curr Med Res Opin; 2013 Dec; 29(12):1719-26. PubMed ID: 24020938
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The anesthetized guinea pig: an effective early cardiovascular derisking and lead optimization model.
    Morissette P; Nishida M; Trepakova E; Imredy J; Lagrutta A; Chaves A; Hoagland K; Hoe CM; Zrada MM; Travis JJ; Zingaro GJ; Gerenser P; Friedrichs G; Salata JJ
    J Pharmacol Toxicol Methods; 2013; 68(1):137-49. PubMed ID: 23649000
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Negative electro-mechanical windows are required for drug-induced Torsades de Pointes in the anesthetized guinea pig.
    Guns PJ; Johnson DM; Weltens E; Lissens J
    J Pharmacol Toxicol Methods; 2012 Sep; 66(2):125-34. PubMed ID: 22516473
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Calculation of QT shift in non clinical safety pharmacology studies.
    Champeroux P; Martel E; Fowler JS; Maurin A; Sola ML; Jude S; Elamrani F; Weyn AA; Laveissiere A; Lala P; Richard S
    J Pharmacol Toxicol Methods; 2009; 59(2):73-85. PubMed ID: 19135537
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ILSI-HESI cardiovascular safety subcommittee dataset: an analysis of the statistical properties of QT interval and rate-corrected QT interval (QTc).
    Chiang AY; Bass AS; Cooper MM; Engwall MJ; Menton RG; Thomas K
    J Pharmacol Toxicol Methods; 2007; 56(2):95-102. PubMed ID: 17588780
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of two external telemetry systems (PhysioJacket and JET) in beagle dogs with telemetry implants.
    Chui RW; Fosdick A; Conner R; Jiang J; Bruenner BA; Vargas HM
    J Pharmacol Toxicol Methods; 2009; 60(1):58-68. PubMed ID: 19426820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Does the sedative agent, JM-1232(-) cause QT prolongation with subsequent torsades de pointes?
    Kato R; Watanabe R; Miki H; Ijiri Y; Hayashi T; Tanaka K
    Life Sci; 2009 Nov; 85(21-22):737-41. PubMed ID: 19833140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Drug-induced QT prolongation: Concordance of preclinical anesthetized canine model in relation to published clinical observations for ten CiPA drugs.
    Koshman YE; Wilsey AS; Bird BM; Endemann AL; Sadilek S; Treadway J; Martin RL; Polakowski JS; Gintant GA; Mittelstadt SW
    J Pharmacol Toxicol Methods; 2020; 103():106871. PubMed ID: 32360993
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Potentially modifiable factors of dofetilide-associated risk of torsades de pointes among hospitalized patients with atrial fibrillation.
    Naksuk N; Sugrue AM; Padmanabhan D; Kella D; DeSimone CV; Kapa S; Asirvatham SJ; Lee HC; Ackerman MJ; Noseworthy PA
    J Interv Card Electrophysiol; 2019 Mar; 54(2):189-196. PubMed ID: 30353374
    [TBL] [Abstract][Full Text] [Related]  

  • 18. K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization.
    Hasumi H; Matsuda R; Shimamoto K; Hata Y; Kaneko N
    Eur J Pharmacol; 2007 Jan; 555(1):54-60. PubMed ID: 17112502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Non-invasive telemetric electrocardiogram assessment in conscious beagle dogs.
    Prior H; McMahon N; Schofield J; Valentin JP
    J Pharmacol Toxicol Methods; 2009; 60(2):167-73. PubMed ID: 19539041
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sample size, power calculations, and their implications for the cost of thorough studies of drug induced QT interval prolongation.
    Malik M; Hnatkova K; Batchvarov V; Gang Y; Smetana P; Camm AJ
    Pacing Clin Electrophysiol; 2004 Dec; 27(12):1659-69. PubMed ID: 15613131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.